Krill oil supplement
Top quality, benefits and side effects

What is in it, composition
Krill oil is a unique all-natural source of several supplements in one including:
Firstly the crucial omega-3 fatty acids EPA and DHA, which are lacking in the diet of many people, particularly those who do not consume enough cold water fish.

In addition to omega-3 fatty acids, krill oil contains the important carotenoid antioxidant astaxanthin which gives the pinkish or reddish color to the softgels. Lastly, it contains vitamins A and E.

Source, pure oil
This high quality krill oil product is derived from Antarctic krill grown in the wild ocean around Antarctica and is processed without application of any solvents.

Krill, what are they?
Krill are small, shrimp-like, ocean-dwelling crustaceans that feed on microscopic phytoplankton and serve as food themselves for larger sea creatures, including whales, sharks and seals.

Krill oil vs fish oil, which one to take?
A krill oil supplement may be used in place of a fish oil supplement, or together with a fish oil supplement. A good option is to use a capsule or two of each. The benefit of fish oils is that they have a higher amount of omega-3 fatty acids. The benefit of krill oil is that it has more antioxidants such as astaxanthin and vitamins A and E.

Suggested Use, dosage, how much to take
As a dietary supplement, take one to three softgels in the morning with food or as recommended by your health care provider.
Updated: December 12 2016
Supplement Facts
Serving Size: 1 Capsule
Servings Per Bottle:  30 Capsules
  Amount Per Capsule % Daily Value
Antarctic Krill Oil 500 mg
Omega-3 Fatty Acids 65 mg  
EPA (Eicosapentaenoic Acid) 25 mg  
DHA (docosahexaenoic acid) 10 mg  
Astaxanthin 750 mcg  
Daily Value or Recommended Daily Intake Not Established
Other Ingredients:Gelatin. Contains Shellfish.

CAUTION: If you are pregnant, breastfeeding, or allergic to shellfish, have a blood coagulation condition or are taking anticoagulants such as warfarin, consult a health care professional prior to use.

Krill Oil or Fish Oil supplements, which is better?
Many people ask whether to take a fish oil supplement or a krill oil supplement. Fish oil has a higher amount of EPA and DHA fatty acids per softgel, however krill oil has the advantage of having vitamin A and vitamin E. Krill oil has a high amount of astaxanthin, a carotenoid with antioxidant properties which gives the krill oil its pinkish or reddish hue. Therefore, one option is to take one or two of each a day with breakfast, or alternate their use.

Side effects, toxicity, safety
Q. Does krill oil have any side effects, any danger or toxicity?
A. No medical reports have yet been published regarding documented cases of krill oil side effects. One possibility is thinning blood making it less coagulable which is often a good thing but if too many krill oil softgels are taken, one needs to be careful if they are taking Coumadin, Plavix, or other blood thinners. See Krill Oil for the latest research on side effects or safety.

Dosage, how much to take
Q. What's the maximum number of krill oil pills one should take a day.
A. Unless your doctor is treating you for a particular condition, we don't see the need to take more than 4 krill oil softgels a day. Take fewer pills if you are also taking fish oil supplements.

Antarctic source
Where does the Krill Oil product carried by Physician Formulas come from? How do I know which brand is best?
A. This krill oil comes from the Antarctic waters. The extraction process for different krill oil products is different, so it is not easy to say that one form of extraction process is better than another form until actual studies are done on humans for prolonged periods comparing one type of krill oil versus other forms of extraction to determine their effects on human health and disease.

Testing for purity
Q. You did a great job qualifying your krill oil except for failing to mention if it has been tested for mercury or other chemicals that are tainting our marine life.
A. Before any raw materials are released for manufacture, a certificate of analysis and HPLC tests are done to make sure no toxins or heavy metals are present.

Q. I understand that krill oil is processed in different countries, do you know what company extracts the krill oil for this product and what country it is made in?
A. The krill oil is extracted in the US, the actual krill is from the Antarctic region. The company that supplies the final product in the US is Cyvex Nutrition.

Q. Does the krill oil supplement have a fishy smell?
A. The softgel smells like fish, but not that much. It does not seem to have much of a fish oil-like after taste.

Q. I have done alot of research on the web for the best krill oil and they all say they are the best. How do i know for sure you are the best?
A. We do not claim the product on our web site is the best. Studies comparing the different brands have not been done, therefore any company who claims their product is the best needs to show published research and proof with studies done in humans.

Q. I have been reading labels on krill oil bottles and many say that it is a combination of fish and krill oil, but does not say the ratio. I am looking to see if your krill oil is 100% without other fish oils in it. I read it is important for your joints to have that type.
A. Yes, ours is 100 percent krill oil, no other oils are added. 

Abuta herb Cissampelos pareira herb
January 20 2016 by Ray Sahelian, M.D.

Abuta is a plant from the Amazon forest. Locals use it as a tonic and for several health conditions. Abuta is used South America to prevent a threatened miscarriage and to stop uterine hemorrhages after childbirth. Also known as Laghupatha, it is an important medicinal plant in Indian traditional system of medicine and is widely used in many countries by different tribes. Despite its wide use in folk medicine, no study has been published regarding its use in humans in the scientific literature.

Abuta antioxidants and substances
Abuta has antioxidant properties and can help the body maintain antioxidant enzyme levels of superoxide dismutase and catalase. Abuta contains numerous compounds including a chalcone-flavone dimer named cissampeloflavone, alkaloids such as hayatinin methochloride, Pareirubrines A and B, grandirubrine, isoimerubrine, and cissampareine.

Availability of the herb
Abuta is sold either in capsules or as a liquid extract.

Research, studies
No human research with abuta root or vine could be found as of 2014.

Rodent studies
Abuta has been helpful to treat arthritis symptoms and has been found to have anti-inflammatory activity.

Abuta species
I've seen it
advertised by a raw material supplier as Abuta grandifolia. I am not sure how different abuta gradifolia is from cissampelos pareira.

A chalcone flavone called cissampeloflavone has been isolated from the herb. Tropoloisoquinoline alkaloids, Pareirubrines A and B, have been isolated, together with the same skeleton alkaloids, grandirubrine and isoimerubrine. Hayatinin methochloride is another alkaloid.
   The roots contain protoberberine alkaloids, hayatidin and hayatin.

Abuta research studies
Antifertility activity of the methanolic leaf extract of Cissampelos pareira in female albino mice.
J Ethnopharmacol. 2007. Department of Chemistry, Cotton College, Guwahati, Assam, India.
Meenakshi Cissampelos pareira is one of the folk medicinal plants commonly used as antifertility agent in some places of India. The aim of the present study was to evaluate the validity of the antifertility effect of the leaf extract. Cissampelos pareira leaf extract, when administered orally, altered the estrous cycle pattern in female mice, prolonged the length of estrous cycle with significant increase in the duration of diestrus stage and reduced significantly the number of litters in albino mice. The plant extract altered gonadotropin release (LH, FSH and prolactin) and estradiol secretion.

Fitoterapia. 2012. New cholinesterase inhibiting bisbenzylisoquinoline alkaloids from Abuta grandifolia. The phytochemical study of the stem bark and wood of Abuta grandifolia (Mart.) Sandwith led to the identification of four bisbenzylisoquinoline alkaloids (BBIQs), namely (R,S)-2 N-norberbamunine (1), (R,R)-isochondodendrine (2), (S-S)-O4″-methyl, Nb-nor-O6'-demethyl-(+)-curine (3), and (S-S)-O4″-methyl, O6'-demethyl-(+)-curine (4), together with the aporphine alkaloid R-nornuciferine (5), all obtained by countercurrent distribution separation (CCD) and identified on the basis of their spectroscopic data. Alkaloids 3 and 4 were new. All the isolated compounds were tested for acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities. 1 was the most active against AChE, whereas 3 and 4 were the most potent against BChE. Interestingly, all tested alkaloids are more potent against BChE than against AChE. This selectivity of cholinesterase (ChE) inhibition could be important in order to speculate on their potential therapeutic relevance.

Can abuta herb be taken the same day as Yohimbe Bark extract?
   We don't know for sure, but yohimbe bark is potent and care must be taken to use a small amount only and not to mix it with other herbs if possible, particularly in high doses.