Acidophilus Lactobacillus by Ray Sahelian, M.D. Acidophilus benefit and side effects

Acidophilus is the brief name for Lactobacillus acidophilus, a bacteria that lives in the gut of humans and has beneficial properties.

Source Naturals - Acidophilus, 300mg, 120 Capsules


Source Naturals Freeze Stabilized Acidophilus is an advanced probiotic product. Acidophilus supports colon health by altering the intestinal ecology to favor "friendly" flora. Acidophilus also manufactures some B-vitamins, especially folic acid.* The acidophilus cells are specially protected before and after freeze drying by a unique stabilizing process.

Acidophilus Supplement Facts
Freeze dried Lactobacillus acidophilus 300 mg †
(approx. 3,000,000,000 viable cells at the time of encapsulation)

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Twice a month you will receive an email with a reivew of several new studies on various supplements and natural medicine topics and their practical interpretation by Ray Sahelian, M.D. We will mention medical research updates on acidophilus benefit.

 

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Probiotics and Prebiotics
Probiotics and prebiotics are two food ingredients that have physiologic effects through the gastrointestinal tract. for more probiotic prebiotic information.

Probiotics have been defined as live microorganisms that (when ingested) have a beneficial effect in the prevention and treatment of specific medical conditions. These microorganisms are believed to exert biological effects through a phenomenon known as colonization resistance, whereby the indigenous anaerobic flora limits the concentration of potentially harmful (mostly aerobic) germs in the digestive tract. Other modes of action, such as supplying enzymes or influencing enzyme activity in the gastrointestinal tract, may also account for some of the other functions that have been attributed to probiotics.

Probiotic bacteria such as Lactobacillus acidophilus or Bifidobacteria are believed to positively affect the immune response by improving the intestinal microbial balance leading to enhanced antibody production and phagocytic (devouring or killing) activity of white blood cells. Bifidobacterium lactis could be an effective probiotic dietary supplement for enhancing some aspects of cellular immunity in the elderly.

Probiotic supplements for children -- Many infants and children may be lacking beneficial bacteria, and supplements could potentially help them get fewer infections. Compared with standard formulas, those containing beneficial "probiotic" organisms seem to reduce the number and duration of diarrhea episodes in infants attending childcare centers. Of two types of probiotics tested -- Lactobacillus reuteri and Bifidobacterium lactis -- Lactobacillus may be the better supplement, according to the report in the medical journal Pediatrics. Probiotic supplements affect the immune response by improving the intestinal microbial balance leading to enhanced antibody production. Another study indicates that children who take probiotic supplements suffer fewer respiratory infections.

Lactobacillus Acidophilus benefit
Acidophilus is of benefit in replenishing colon bacteria after antibiotic use. Acidophilus may be of benefit in irritable bowel syndrome. Acidophilus may not benefit those who use it during acute diarrhea.

Availability of Acidophilus
You can find acidophilus in powder, liquid, acidophilus tablet or capsule, and even chewable acidophilus.

Acidophilus side effects
No major side effect with acidophilus have been reported thus far.

Acidophilus Benefit Research Update
Clinical effects of Lactobacillus acidophilus strain L-92 on perennial allergic rhinitis: a double-blind, placebo-controlled study.
J Dairy Sci. 2005 Feb;88(2):527-33.
Studies in animals have suggested that lactic acid bacteria alleviate allergic diseases, however, little information is available on their clinical effect on allergy in humans. Thus, we examined the efficacy of orally administered Lactobacillus acidophilus strain L-92 (L-92) on perennial allergic rhinitis. In a randomized, double-blind, placebo-controlled clinical trial, 49 patients with perennial allergic rhinitis were randomized to receive either 100 mL of heat-treated fermented milk containing L-92 (n = 25) or acidified milk without lactic acid bacteria (placebo; n = 24) for 8 wk. The severity of symptoms was evaluated based on the changes in the scores of clinical symptoms. Oral administration of milk fermented with acidophilus resulted in a statistically significant improvement of nasal symptom-medication scores. Ocular symptom-medication scores of patients in the L-92 intervention group tended to improve compared with those in the placebo group. In addition, clear decreases of the scores of swelling and color of the nasal mucosa were observed in the acidophilus intervention group at 6 and 8 wk after the start of ingestion of fermented milk. There were no significant differences in serum antihouse dust mite immunoglobulin E levels nor in T helper type 1/T helper type 2 ratio between the 2 groups. These results suggest that oral administration of acidophilus can alleviate the symptoms of perennial allergic rhinitis, however, statistically significant changes were not shown in blood parameters.

The effect of Lactobacillus acidophilus and Bifidobacterium spp. administration on the morphology of the gastrointestinal tract, liver and pancreas in piglets.
Pol J Vet Sci. 2005;8(1):29-35.
The aim of the study was to investigate the influence of administration of probiotic bacteria on morphology of the gastrointestinal tract, liver and pancreas. The experiment was performed on 15 piglets at the age from 3 to 35 days, intragastrically administered with Bifidobacterium breve, B. animalis, and Lactobacillus acidophilus bacteria. The administration of bacteria, especially of Lactobacillus acidophilus, caused an increase in the number of lymphocytes and lymphoid cells in lamina propria and intraepithelial lymphocytes in the small intestine. Enhanced proliferation of crypt cells was observed in the crypts of intestinal glands; however, there were no statistically significant differences in the PCNA index between the control and probiotic-administered groups. The performed study showed that the administration of probiotic bacteria has no negative impact on the morphology of the gastrointestinal tract, liver and pancreas and is found beneficial to its functioning and immune processes.

Antioxidative activity of lactobacilli measured by oxygen radical absorbance capacity.
J Dairy Sci. 2005 Apr;88(4):1352-7.
The reducing ability and antioxidative activity of some species of Lactobacillus were compared under in vitro conditions. Cultures of Lactobacillus delbrueckii ssp. lactis, Lactobacillus delbrueckii ssp. bulgaricus, Lactobacillus acidophilus, and Lactobacillus casei were grown at 37 degrees C in de Man, Rogosa, Sharpe (MRS) broth supplemented with 0.5% 2,3,5 triphenyl tetrazolium chloride (TTC) to evaluate reducing activity. Reduced TTC was extracted from the cultures with acetone, and the intensity of the red color measured colorimetrically at 485 nm was an indication of reducing activity. The results from this study show that these cultures can provide a source of dietary antioxidants. Furthermore, selection of cultures that produce antioxidants as starters could provide yet another health or nutritional benefit from cultured or culture-containing dairy products.

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Lactobacillus acidophilus questions
Q. Is headache an acidophilus side effect?
   A. We doubt that headache is an acidophilus side effects.

Q. Is it better to take acidophilus in tablet or capsule form?
   A. Acidophilus capsule or tablet or liquid acidophilus are all fine.

Q. Is acidophilus lactobacillus yogurt a good way to ingest these bacteria?
   A. It depends. You have to read the label of the acidophilus lactobacillus yogurt to make sure adequate amounts of the bacteria have been added.

Q. Can acidophilus be taken during pregnancy?
   A. Probably. Acidophilus should be safe during pregnancy but asking for your doctor's approval is a good idea.