Agrimony herb health benefit information
Complementary medicine newsletter.
April 10 2016 by Ray Sahelian, M.D.

The yellow, star-shaped blossoms of Agrimonia eupatoria, have long been used for medicinal purposes. I cannot find human studies to indicate how agrimony would be useful in hepatitis, diabetes, or other health conditions.

Chemical composition
The agrimony herb has a number of polyphenols which are important for health: Proanthocyanidins, flavan-3-ols (catechin and procyanidins B1, B2, B3, B6, B7, C1, C2 and epicatechin-epicatechin-catechin), quercetin 3-O-glucoside, quercetin 3-O-galactoside, kaempferol 3-O-glucoside, kaempferol, apigenin 6-C-glucoside and various phenolic acids have been identified. Many of these compounds have anti-inflammatory activity.

Agrimony for Hepatitis
Inhibition of hepatitis B virus by an aqueous extract of Agrimonia eupatoria.
Phytother Res. 2005. Cell Biology Laboratory, Korea Research Institute of Bioscience and Biotechnology, Daejon, Republic of Korea.
Inhibition of hepatitis B surface antigen - HBsAg - release against hepatitis B virus (HBV) was investigated in an aqueous extract prepared from the aerial parts (stems and leaves) of Agrimony. This inhibitory activity was also shown with the aqueous extracts of two other species of the genus Agrimonia: A. pilosa and A. coreana pilosella. These results suggest that some plants of the genus Agrimony contain potential antiviral activity against hepatitis B virus.

Agrimony for diabetes, blood sugar
Actions of the traditional anti-diabetic plant, Agrimony eupatoria effects on hyperglycaemia, cellular glucose metabolism and insulin secretion.
Br J Nutrition. 1998.
Agrimony eupatoria has been documented as a traditional treatment of diabetes. Here, the effects of dietary administration of agrimony on streptozotocin (STZ)-diabetic mice and on in vitro glucose uptake and glucose metabolism, and on insulin secretion by BRIN-BD11 cells were investigated. Agrimony incorporated into the diet (62.5 g/kg) and drinking water (2.5 g/l) countered the weight loss, polydipsia, hyperphagia and hyperglycaemia of STZ-diabetic mice. Conclusion: These results demonstrate the presence of antihyperglycaemic, insulin-releasing and insulin-like activity in Agrimony eupatoria.

BMC Complement Altern Med. 2014. Glucosidase inhibitory activity and antioxidant activity of flavonoid compound and triterpenoid compound from Agrimonia Pilosa In Chinese traditional medicine, Agrimonia pilosa Ledeb exhibits great effect on treatment of type 2 diabetes mellitus