Alli weight loss pill
April 16 2016 by Ray Sahelian, M.D.
GlaxoSmithKline Consumer Healthcare announces in June,
2006 that the FDA approved Alli, the weight loss product orlistat 60 mg capsules
for over-the-counter use in the United States.
Xenical (orlistat 120 mg capsules) will remain available by prescription for
those who should be treated under the care of a physician. Xenical will continue
to be manufactured and sold by Roche.
My comments: I would like to wait about three to five years after Alli has been on the market to find out if there are any long term health concerns when masses of people uses this weight loss pill product. The decrease in fat absorption could result in the loss of vitamin A, vitamin E, and other fat soluble vitamins. These can be replaced by taking a multivitamin. However, there could also be a loss in carotenoids and important fatty acids such as fish oils. What are the long term health consequences of these losses on vision, cardiovascular health, and brain function?
2011 -- The consumer advocacy group Public Citizen is urging the FDA to immediately pull two weight loss drugs, Xenical and Alli, from the market. The group says the drugs' risk for liver, pancreas, and kidney damage greatly outweighs any potential weight loss benefits.
Research and review
Alli marketers claim this product helps people lose 50 per cent more weight than with diet alone. Alli is the only FDA-approved weight-loss product available to consumers without a prescription. Alli will be in stores nationwide by summer 2007. Steven L. Burton, Vice President, Weight Control, GlaxoSmithKline Consumer Healthcare. says "Alli is more than a pill - it's a comprehensive program that works in conjunction with a sensible diet to increase weight loss. Because weight loss doesn't happen overnight, we're starting to educate consumers now about the importance of realistic expectations, gradual weight loss and lifestyle changes. That's the way to see results, and with Alli , we know they can do it."
Selection of Alli name
GlaxoSmithKline Consumer Healthcare selected Alli as the brand name because it conveys the concept of partnership with consumers in their weight-loss efforts. Caroline Apovian, M.D., Director of the Center for Nutrition and Weight Management at Boston Medical Center welcomed the FDA decision. "I applaud the Alli program for stressing the importance of a reduced-calorie, low-fat diet in conjunction with a weight-loss medicine proven to be safe and effective. This lines up with research that shows even modest, gradual weight loss provides significant health benefits." Caroline Apovian adds.
How to Use this medication to lose weight
Alli is indicated for weight loss in overweight adults 18 years and older when used along with a reduced-calorie, low-fat diet. The recommended dose of alli is one 60 mg capsule three times a day with meals containing fat.
Taken at meal-time, alli works by blocking about 25 per cent of the fat in the food a person eats. Because of the way it works, alli must be used in conjunction with a reduced-calorie, low-fat diet containing about 15 grams of fat per meal. The guides and information supplied in the alli package help the consumer to control the amount of fat in their meals, and to follow an appealing, reduced-calorie, low-fat diet.
Skeptics mention the failure of short-term medication use
to achieve long-term results (due to the chronic and recurrent condition of
obesity); common perception of obesity as a lifestyle choice; difficulty to
treat obesity in the primary care setting; less than desired weight-loss results
with medications; misuse of medications for cosmetic reasons; and unfavorable
history of other anti-obesity drugs that were withdrawn in previous decades.
Alli side effects
Consuming a meal with too much fat, while taking it, can result in bowel changes such as having an urgent need to use the bathroom. These changes, called treatment effects, generally occur in the first weeks of treatment, can be managed by following the recommended diet with about 15 grams of fat per meal. Users should take a multivitamin once a day, because alli can reduce the absorption of some vitamins.
A higher dose of orlistat has been marketed as the prescription drug Xenical (orlistat 120 mg capsules) in the U.S. since 1999. Orlistat experience in more than 25 million patient treatments and more than 100 clinical studies with more than 30,000 patients is unprecedented. One of these studies with Xenical is the four-year landmark XENDOS trial conducted by Roche, its inventor and manufacturer. This study is the longest study ever conducted for a weight-loss medicine.
I am aware of Alli weight loss diet pill, and others by prescription, how do I know which one is best for me>?
Alli xenical diet pill is promoted heavily and otc products are popular due to media attention, but without trying it is difficult to know whether it will work better than other over the counter or prescription products.