Ascorbic acid is required for the growth and repair
of tissues. Ascorbic acid is necessary to form
collagen, an important
protein used to make skin, scar tissue, tendons, ligaments, and blood
vessels. Ascorbic acid is also essential for the healing of wounds, and
for the repair and maintenance of cartilage, bones, and teeth.
Availability of Ascorbic Acid supplement
Countless ascorbic acid products and formulas are sold. Ascorbic
acid comes by itself in dosage ranging from 100 to 1000 mg, it comes as
ascorbic acid powder, as Ester C, combined in
multivitamin formulas,
combined with rose hips, etc.
MultiVit Rx - Lasts two to four
months.
High Quality Daily Vitamins and Minerals with Ascorbic Acid and
Rose hips - 500 mg
Developed by Ray Sahelian, M.D.
Manufactured by a FDA-approved and GMP-certified facility.

This
MultiVit Rx product
has 500 mg of ascorbic acid and rose hips per daily dose. Click the link for full
details.

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Ascorbic Acid in Cosmetics
L-Ascorbic Acid, Calcium Ascorbate, Magnesium
Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl
Phosphate are used in cosmetic formulations primarily as antioxidants. Ascorbic
Acid is used as an antioxidant and pH adjuster in a large variety of cosmetic
formulations, the majority of which are hair dyes and colors at concentrations
between 0.3% and 0.6%. Calcium Ascorbate and Magnesium Ascorbate are described
as antioxidants and skin conditioning agents--miscellaneous for use in
cosmetics, but are not currently used. Sodium Ascorbyl Phosphate functions as an
antioxidant in cosmetic products and is used at concentrations ranging from
0.01% to 3%. Magnesium Ascorbyl Phosphate functions as an antioxidant in
cosmetics and was reported being used at concentrations from 0.001% to 3%.
Sodium Ascorbate also functions as an antioxidant in cosmetics at concentrations
from 0.0003% to 0.3%. Related ingredients (Ascorbyl Palmitate, Ascorbyl
Dipalmitate, Ascorbyl Stearate, Erythorbic Acid, and Sodium Erythorbate) have
been previously reviewed by the Cosmetic Ingredient Review (CIR) Expert Panel
and found "to be safe for use as cosmetic ingredients in the present practices
of good use." Ascorbic Acid is a generally recognized as safe (GRAS) substance
for use as a chemical preservative in foods and as a nutrient and/or dietary
supplement. Calcium Ascorbate and Sodium Ascorbate are listed as GRAS substances
for use as chemical preservatives. L-Ascorbic Acid is readily and reversibly
oxidized to L-dehydroascorbic acid and both forms exist in equilibrium in the
body.
Ascorbic Acid and Pregnancy
Ascorbic Acid Research
update
Antioxidant effects of combined vitamins C and E
in acute myocardial infarction. The randomized, double-blind, placebo
controlled, multicenter pilot Myocardial Infarction and VITamins (MIVIT)
trial.
Kardiol Pol. 2005 Apr;62(4):344-50.
There is a large body of evidence that reactive oxygen species (ROS)
produced during myocardial ischemia and reperfusion play a crucial role in
myocardial damage and endothelial dysfunction. The MIVIT pilot trial was
designed to test the effects of antioxidant ascorbic acid and vitamin E on
the clinical outcome of patients with AMI. METHODS and RESULTS: In this
randomized, double-blind, multicenter trial, 800 patients (mean age 62)
with AMI were randomly allocated to receive, on top of routine medication,
one of two treatments: ascorbic acid (1000 mg/12 h infusion) followed by
1200 mg/24 h orally and vitamin E (600 mg/24 h) or matching placebo for 30
days. Primary end point (composite of in-hospital cardiac mortality,
non-fatal new myocardial infarction, VT/VF/ asystole, shock / pulmonary
edema) occurred less frequently in patients treated with antioxidants.
CONCLUSIONS: This randomized pilot trial shows that supplementation with
antioxidant vitamins ascorbic acid and vitamin E is safe and seems to
positively influence the clinical outcome of patients with AMI.
Ascorbate increases human oxaluria and
kidney
stone risk.
J Nutr. 2005 Jul;135(7):1673-7. Massey LK, Liebman M, Kynast-Gales SA.
Department of Food Science and Human Nutrition, Washington State
University, Spokane, WA
Currently, the recommended upper limit for ascorbic acid intake is 2000
mg/d. However, because ascorbic acid is endogenously converted to oxalate
and appears to increase the absorption of dietary oxalate, supplementation
may increase the risk of kidney stones. The effect of ascorbic acid
supplementation on urinary oxalate was studied in a randomized, crossover,
controlled design in which subjects consumed a controlled diet in a
university metabolic unit. Stoneformers (n = 29; SF) and age- and
gender-matched non-stoneformers (n = 19; NSF) consumed 1000 mg ascorbic
acid twice each day with each morning and evening meal for 6 d (treatment
A), and no ascorbic acid for 6 d (treatment N) in random order. After 5 d
of adaptation to a low-oxalate diet, participants lived for 24 h in a
metabolic unit, during which they were given 136 mg oxalate, including 18
mg 13C2 oxalic acid, 2 h before breakfast; they then consumed a controlled
very low-oxalate diet for 24 h. Of the 48 participants, 19 (12
stoneformers, 7 non-stoneformers) were identified as responders, defined
by an increase in 24-h total oxalate excretion > 10% after treatment A
compared with N. Responders had a greater 24-h Tiselius Risk Index (TRI)
with AA supplementation because of a 31% increase in the percentage of
oxalate absorption and a 39% increase in endogenous oxalate synthesis with
treatment A than during treatment N. The 1000 mg ascorbic acid twice each
day increased urinary oxalate and TRI for calcium oxalate kidney stones in
40% of participants, both stoneformers and non-stoneformers. vitamin c ascorbic acid.
Ascorbic acid
supplementation to prevent premature rupture of the chorioamniotic
membranes: a randomized trial.
American J Clinical Nutr. 2005 Apr;81(4):859-63.
Public Health Research Branch, National Institute of Perinatology, Mexico
City, Mexico.
Ascorbic acid is involved in the synthesis and degradation of collagen
and is important for maintenance of the chorioamniotic membranes.
Inadequate availability of ascorbic acid during pregnancy has been
proposed as a risk factor for premature rupture of the chorioamniotic
membranes (PROM). The objective of the study was to evaluate the
effectiveness of 100 mg ascorbic acid per day in preventing PROM. A
controlled double-blind trial was performed. Pregnant women (n = 126) in
their 20th wk of gestation were invited; 120 accepted and were randomly
assigned to 2 groups (100 mg ascorbic acid or placebo). Every 4 wk, plasma
and leukocyte ascorbic acid concentrations were measured, and each subject
was evaluated for cervicovaginal infection. The incidence of PROM was
recorded for each group as an indicator of the protective effect of
ascorbic acid supplementation. RESULTS: One hundred nine patients finished
the study. Mean plasma ascorbic acid concentrations decreased
significantly throughout the pregnancy in both groups, and there were no
significant differences between groups. Between weeks 20 and 36, mean
leukocyte ascorbic acid concentrations decreased from 17.5 to 15.23 microg/10(8)
cells in the placebo group and increased from 17.26 to 22.17 microg/10(8)
cells in the supplemented group (within- and between-group differences.
The incidence of PROM was 14 per 57 pregnancies (24%) in the placebo group
and 4 per 52 pregnancies (7%) in the supplemented group. CONCLUSION: Daily
supplementation with 100 mg vitamin C after 20 wk of gestation effectively
lessens the incidence of PROM. l ascorbic acid
Ascorbic acid emails
Q. Is
erythorbic acid the same as ascorbic acid?
A. Erythorbic acid is a stereoisomer of ascorbic acid
with similar properties.
Q. Can ascorbic acid be taken the same day as
vinpocetine?
A. We don't see any reason why not.
Q. I wish to purchase 2 to 4 oz of L ascorbic acid
crystals.
A. The best way is to do a google search since we are
not familiar with a liquid ascorbic acid crystals product .
Q. I've been all over the internet trying to find
the answer to this question, but nobody makes it clear. I'm hoping you can
help. Is l-ascorbic acid exactly the same thing as ascorbic acid? I need
to purchase some l-ascorbic acid, and I don't know if the bottles labelled
ascorbic acid are the same.
A. L ascorbic acid and ascorbic acid are the same as far as when
found in a supplement bottle.
Q. I've heard good things about
resveratrol.
Would it interact with ascorbic acid in a bad way if I took them both
together?
A. I have not seen any indication that it would.