AstraZeneca Plc medications and products
June 3 2016 by
Ray Sahelian, M.D.

AstraZeneca is Europe's third-biggest drugmaker. AstraZeneca is one of the world's leading pharmaceutical companies. The broad product portfolio of AstraZeneca includes: Arimidex (cancer, tumors), Crestor (cardiovascular, cholesterol), Nexium (gastrointestinal disease), Seroquel (schizophrenia) and Symbicort (asthma and chronic obstructive pulmonary disease). AstraZeneca Sales in 2005 totaled $24 billion, with an operating profit of $6.5 billion.

AstraZeneca's blood-thinning drug Brilinta cut the risk of death or heart attack in patients with a history of previous attacks, according to a major clinical trial that will boost hopes for the closely watched product.


Top three selling drugs for AstraZeneca:
Crestor. cholesterol fighter - In 2007, AstraZeneca Plc has won U.S. approval to market its cholesterol-lowering drug Crestor, the trade name for the generic rosuvastatin, to treat atherosclerosis. Crestor is the first of the widely used statin family of cholesterol drugs -- the world's top-selling prescription drugs -- to win approval to treat atherosclerosis.
   Crestor is by AstraZeneca for the use as a medication for high cholesterol, but there are natural alternatives.

Nexium is its best-selling heartburn and stomach ulcer pill at $5-billion-a-year.

Seroquel is a pharmaceutical drug used for schizophrenia - AstraZeneca PLC has received approval from the U.S. Food and Drug Administration for a new formulation of its popular Seroquel schizophrenia treatment, making it the first medicine to treat both the manic and depressive sides of bipolar disorder. Seroquel, launched by the Anglo-Swedish company in 1997, is already used to treat acute manic episodes associated with bipolar disorder and schizophrenia. The FDA approval adds the treatment of patients with depressive episodes. Seroquel is one of AstraZeneca's top-selling drugs, with total sales of $2.8 billion in 2005.


Full line of products from AstraZeneca

Accolate, Accoleit, Vanticon - zafirlukast - Respiratory & Inflammation
Apatef, Cefotan - cefotetan - Infection
Arimidex - anastrozole - for post menopausal breast cancer

Atacand - candesartan cilexetil - Cardiovascular
Bambec, Oxeol - bambuterol - Respiratory & Inflammation
Bricanyl - terbutaline - Respiratory & Inflammation
Tamoxifen was sold by AstraZeneca Plc under the name Nolvadex but is now marketed by several generic drug makers.


Financial outlook
2007 - AstraZeneca Plc plans to cut some 3,000 jobs, or 4.6 percent of its global workforce, to ensure future profit growth as generic competition bites and top seller Nexium starts to mature. The move follows plans by Pfizer Inc., the world's biggest drugmaker, to reduce its staff numbers by 10 percent and reflects tough times for manufacturers facing more generic rivals, weak pipelines and pressure on prices.