Bearberry is also known as Uva Ursi. Bearberry (Arctostaphylos bearberry) is an evergreen shrub that has long been popular for fighting urinary tract or bladder infections. Bearberry gets its name since the berries are popular with bears.

How is Bearberry available?
You will find Bearberry as a tea, tinctures, capsules, and bearberry extracts.

Bearberry side effects
I found one medical report of damage to the retina in one person who used bearberry daily for 3 years. No other side effects have been reported in the medical literature.

Bearberry Research studies
Bull's-eye maculopathy secondary to herbal toxicity from Bearberry.
Am J Ophthalmol. 2004 Jun;137(6):1135-7. Wang L, Del Priore LV. Department of Ophthalmology and Visual Sciences, Weill Medical College, Cornell University, New York, NY
To report a case of bilateral bull's-eye maculopathy in a patient who ingested Bearberry, a known inhibitor of melanin synthesis, for 3 years before the onset of symptoms. Observational case report. Both eyes of a female patient were examined in the clinical practice setting. A 56-year-old woman who ingested Bearberry for 3 years noted a decrease in visual acuity within the past year. Ocular examination including fluorescein angiography revealed a typical bull's-eye maculopathy bilaterally. Bearberry is a known inhibitor of melanin synthesis. It is necessary to broaden the list of potential retinal toxic drugs to include herbal adjuvants such as Bearberry and to elicit a history of their use in patients with unexplained ocular findings.

Botanical medicines for the urinary tract.
World J Urol. 2002 Nov;20(5):285-93. Yarnell E.
Four important categories of urologic herbs, their history, and modern scientific investigations regarding them are reviewed. Botanical diuretics are discussed with a focus on Solidago spp (goldenrod) herb, Levisticum officinale (lovage) root, Petroselinum crispus (parsley) fruit, and Urtica dioica (stinging nettle) herb. Urinary antiseptic and anti-adhesion herbs, particularly Arctostaphylos Bearberry (uva-uri) leaf, Juniperus spp (juniper) leaf, and Vaccinium macrocarpon (cranberry) fruit are reviewed. The antinephrotoxic botanicals Rheum palmatum (Chinese rhubarb) root and Lespedeza capitata (round-head lespedeza) herb are surveyed, followed by herbs for symptoms of benign prostatic hyperplasia, most notably Serenoa repens (saw palmetto) fruit, Urtica dioica root, and Prunus africana (pygeum) bark.

Urinary excretion and metabolism of arbutin after oral administration of Arctostaphylos uvae ursi extract as film-coated tablets and aqueous solution in healthy humans.
J Clin Pharmacol. 2002 Aug;42(8):920-7.
Bearberry leaves and preparations made from them are traditionally used for urinary tract infections. The urinary excretion of arbutin metabolites was examined in a randomized crossover design in 16 healthy volunteers after the application of a single oral dose of bearberry leaves dry extract. There were two groups of application using either film-coated tablets (FCT) or aqueous solution (AS). The urine sample analysis was performed by a validated HPLC coolarray method (hydroquinone) and a validated capillary electrophoresis method (hydroquinone-glucuronide, hydroquinone-sulfate). No significant differences between the two groups were found in the metabolite patterns detected (hydroquinone, hydroquinone-glucuronide, and hydroquinone-sulfate).

A single extraction step in the quantitative analysis of arbutin in bearberry (Arctostaphylos uva-ursi) leaves by high-performance liquid chromatography.
Phytochem Anal. 2001 Sep-Oct;12(5):336-9.
A fast and simple extraction procedure coupled with a simple HPLC method has been developed in order to determine the arbutin content of leaves of Arctostaphylos uva-ursi plants grown at four different geographical sites and collected during two different seasons. Using the optimised analytical system, the arbutin content of bearberry leaves was found to vary from 6.30 to 9.16% expressed on a dry weight basis. Autumn is shown to be a better period than spring for the collection of plant material in order to obtain the highest yield of arbutin.