Benefit of CoQ10 supplement Health benefit of Co Q10

Studies regarding the benefit of CoQ10 have mostly focused on its benefit involving certain types of cardiovascular diseases, including congestive heart failure and hypertension. However, CoQ10 may also benefit those with high cholesterol and diabetes. Studies with CoQ10 and Parkinson's disease have not yielded consistent results. We still have a long way to go to determine the proper clinical role and benefit of CoQ10. In the meantime, do not assume that the benefit of CoQ10 depends on the highest dose that you take. It is possible that after a certain dosage, CoQ10 could lose its benefit. We don't think more than 50 mg of CoQ10 is required by most people.

See also CoQ10 supplement (Coenzyme Q10) 30 mg, 50 mg, 60 mg, and 100 mg
 

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Co-Q10 benefit for Parkinson
Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson's disease.
Exp Neurol. 2004 Aug;188(2):491-4.
The safety and tolerability of high dosages of co Q10 were studied in 17 patients with Parkinson's disease in an open label study. The subjects received an escalating dosage of co Q10, 1200, 1800, 2400, and 3000 mg/day with a stable dosage of vitamin E (alpha-tocopherol) 1200 IU/day. The plasma level of co Q10 was measured at each dosage. Thirteen of the subjects achieved the maximal dosage, and adverse events were typically considered to be unrelated to co Q10. The plasma level reached a plateau at the 2400 mg/day dosage and did not increase further at the 3000 mg/day dosage. Our data suggest that in future studies of co Q10 in PD, a dosage of 2400 mg/day (with vitamin E/alpha-tocopherol 1200 IU/day) is an appropriate highest dosage to be studied.

Benefit of CoQ10 for Energy Production
CoQ10 is an antioxidant necessary for normal heart function and optimal cellular energy production.

Benefit of CoQ10 for Heart Health

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