Calcium D Glucarate research by Ray Sahelian, M.D. Calcium D Glucarate health benefit

D-glucarate is the anionic form of D-glucaric acid. D Glucarate is naturally found in some vegetables and fruits, including cruciferous vegetables, bean sprouts and apples. D-glucarate in the form of its calcium salt, calcium D-glucarate, is marketed as a nutritional supplement.

Source Naturals, Calcium D-Glucarate, 500 mg
Source Naturals Calcium D-Glucarate includes the patented compound glucarate which has been shown to enhance the major detoxification pathways in the body.  Calcium D-Glucarate, the calcium salt of D-glucaric acid, is found naturally in the human body and in a variety of fruits and vegetables.  Animal studies have shown that Calcium D-Glucarate inhibits B-glucuronidase, thereby enhancing the process of glucuronidase, in which foreign organic compounds, fat-soluble toxins and excess steroid hormones such as estrogen are detoxified and excreted from our bodies.

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Calcium D Glucrate in food
Calcium Glucarate is a naturally occurring non-toxic compound present in fruits, vegetables and seeds of some plants. Dietary calcium glucarate, a sustained-release from of glucarate, elevates the blood level of D-glucaro-1,4-lactone which suppresses blood and tissue beta-glucuronidase activity.

Calcium D Glucarate benefit
Oral supplementation of calcium-D-glucarate inhibits beta-glucuronidase, an enzyme produced by colonic microflora and involved in Phase II liver detoxification. Elevated beta-glucuronidase activity is associated wire an increased risk for various cancers, particularly hormone-dependent cancers such as breast, prostate, and colon cancers.

Calcium D Glucarate summary
At this time I could not find any human studies with calcium d glucarate to determine the effectiveness of this natural supplement in terms of prevention or treatment of cancer. Until such studies are done, we can only guess at the effectiveness of this supplement, and even if it works, a lot of research needs to be done to determine what the ideal dosage would be and how long this nutrient needs to be used.