Cephalexin by
Ray Sahelian, M.D.
Brand names: Keflex, Keftabs, Biocef
Cephalexin belongs to a class of
antibiotics called cephalosporins. They are
similar to penicillin in action and side effects. They stop or slow the growth
of bacterial cells by preventing bacteria from forming the cell wall that
surrounds each cell. The cell wall protects bacteria from the external
environment and keeps the contents of the cell together. Without a cell wall
bacteria are not able to survive. Bacteria that are susceptible to cephalexin
include Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae,
E. coli and several others.
How is Cephalexin Available?
Cephalexin is prescribed as Tablets: 250 and 500 mg, and 1 g. Capsules: 250,
333, 500 and 750 mg. Cephalexin Powder for Suspension: 125, and 250 mg/5 ml.
Conditions where Cephalexin is Prescribed
Cephalexin is
used to treat infections caused by bacteria that are susceptible to the effects
of cephalexin. Common infections that are treated with cephalexin include
infections of the middle ear, tonsils, throat, larynx (laryngitis), bronchi
(bronchitis) and pneumonia. It also is used for treating urinary tract,
skin and
bone infections.
Cephalexin Dosage
The dose of
cephalexin for adults is 1 to 4 grams in divided doses. Children are treated
with 25-100 mg/kg/day in divided doses.
Cephalexin and Pregnancy, Nursing
Based on
limited evidence, cephalosporins, including cephalexin, appear to be safe when
used during pregnancy. Most cephalosporins are excreted in breast milk. Nursing
mothers should avoid using cephalosporins or stop breastfeeding while taking a
cephalosporin.
Cephalexin Side Effects
The most common side effects of cephalexin are diarrhea, nausea, abdominal pain, vomiting, headaches, dizziness, skin rash, fever, abnormal liver tests and vaginitis. Individuals who are allergic to penicillin may also be allergic to cephalexin.
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