Chrysanthemum indicum herb by Ray Sahelian, M.D.
April 6 2015

Chrysanthemum herbal extract and tea has has been used for a number of medical conditions including recovery from influenza and as a "cooling" herb. According to traditional Chinese medicine chrysanthemum tea can be helpful in the prevention of sore throat and promote the reduction of fever. Chrysanthemum tea is used for varicose veins and atherosclerosis. One small study in dogs showed chrysanthemum flower water extract to dilate coronary arteries.

Chrysanthemum composition
Sesquiterpenes, kikkanols A, B, and C, flavonoids.

Properties and how it works
One study show chrysanthemum is able to inhibit the conversion of xanthine to uric acid which may perhaps make this herb helpful for gout, although human trials are needed before making any recommendations.

Planetary herbals - Rehmannia Endurance with Chrysanthemum
Planetary Formulas Rehmannia Endurance is based on the classic Chinese tonifier Rehmannia Six: Liu Wei Di Huang Wan, one of the most strengthening tonics of Chinese herbalism. Traditionally it was used for those who are tired and run down from overwork and inadequate rest due to a fast paced-lifestyle.

Supplement Facts:
Calcium
Rehmannia Root herb
Poria Cocos Sclerotium
Tree Peony Root bark
Dioscorea Root
Alisma Rhizome
He Shou Wu Root (Fo Ti)
Chrysanthemum Flower
Ligustrum Seed
Saw Palmetto Berry
Lycii Fruit Extract
Cornus Fruit

Chrysanthemum cream for rosacea
People with rosacea have facial skin that looks red or flushed. In a 12-week study of 246 people, a 1 per cent Chrysanthellum indicum cream was found to significantly improve rosacea compared with a placebo. The cream is also called golden chamomile.

Chrysanthemum Indicum Research
Phytother Res. 2015. The Anti-Osteoporosis and Antioxidant Activities of Chemical Constituents from Chrysanthemum indicum Flowers.

Medicinal flowers. VI. Absolute stereostructures of two new flavanone glycosides and a phenylbutanoid glycoside from the flowers of Chrysanthemum indicum L.: their inhibitory activities for rat lens aldose reductase.
Chem Pharm Bull (Tokyo). 2002.
Two new flavanone glycosides, eriodictyol 7-O-beta-D-glucopyranosiduronic acids, and a new phenylbutanoid glycoside were isolated from the flowers of Chrysanthemum indicum L. cultivated in China together with eight flavonoids. Both of the new flavanone glycosides were found to show inhibitory activity for rat lens aldose reductase.

Studies on the antilipid peroxidation of nine sorts of Chinese herbal medicines with the function of protecting liver Zhong Yao Cai. 1997 Dec;20(12):624-6.
The antilipid peroxidation of nine sorts of Chinese herbal medicines with the function of protecting liver, including Salivia miltiorrhiza, Hypericum japonicum, Scutellaria baicalensis, Callicarpa cathayana, Chrysanthemum indicum, Paeonia latiflora, Lysimachia christinae, Ligustrum lucidum, Patrinia villosa on hepatic homogenate of rat were tested. It was found that all tested medicines showed inhibition with dose-effect relationship, the inhibitory rate of L1 and Pv were lower than the other's. All results showed that these Chinese herbal medicines have strong antilipid peroxidation and are natural oxidation inhibitor. It was suggested that their function of protecting liver and others have relationship with the antioxidation.

Inhibition of xanthine oxidase by some Chinese medicinal plants used to treat gout.
J Ethnopharmacol. 2000.
The enzyme xanthine oxidase catalyses the oxidation of hypoxanthine to xanthine and then to uric acid, which plays a crucial role in gout. A total of 122 traditional Chinese medicinal plants, selected according to the clinical efficacy and prescription frequency for the treatment of gout and other hyperuricemia-related disorders, have been evaluated for the enzyme inhibitory activity. The most active was the methanol extract of the twig of Cinnamomum cassia (Lauraceae) (IC(50), 18 microg/ml), which was followed immediately by those of the flower of Chrysanthemum indicum (Asteraceae) (IC(50), 22 microg/ml) and the leaves of Lycopus europaeus (Lamiatae) (IC(50), 26 microg/ml). Among the water extracts, the strongest inhibition of the enzyme was observed with that of the rhizome of Polygonum cuspidatum. The IC(50) value of allopurinol used as a positive control was 1.06 microg/ml. The study demonstrated that the effects for these medicinal plants used for the gout treatment were based, at least in part, on the xanthine oxidase inhibitory action.

Effects of Chrysanthemum indicum Linn. on coronary, vertebral, renal and aortic blood flows of the anesthetized dog.
Arch Int Pharmacodyn Ther. 1987.
The hemodynamic effects of the water extract of flower of Chrysanthemum indicum Linn. and adenosine were examined in anesthetized open-chest dogs. These results indicate that Chrysanthemum indicum directly and uniformly produces coronary and systemic vasodilation with renal vasoconstriction, and that adenosine directly produces vasoconstriction in renal vasculature and vasodilation which is more potent in coronary vasculature than in systemic ones.

Protective effect of Chrysanthemum indicum L extract (CI-2) on myocardial injury in cultured neonatal rat heart cells deprived of oxygen and glucose
Zhong Xi Yi Jie He Za Zhi. 1981.