In men with ED, Viagra and Cialis were both effective and well tolerated. After treatment with each alone, 29% of men chose Viagra and 71% chose Cialis for ED therapy during an 8-week extension. British Journal of Urology Int. 2005.

A 32-year-old male presented with recurrent nosebleeds during sexual intercourses. The patient controlled the bleeding each time with sponge packs and gauzes. During the consultation, he volunteered that the trigger for the nosebleeds appeared to have been the use of phosphodiesterase (PDE)-5 inhibitors, Viagra and Cialis. This first report of Cialis side effect of epistaxis after PDE-5 inhibitors in a young patient opens the possibility that in the next years the number of similar cases might increase. International Journal of Impotence Research. 2006.

A healthy 46-year-old man went to the Emergency Department with a 36-hour history of persistent, painful erection after taking the cyclic guanylyl monophosphate-specific phosphodiesterase 5 inhibitor Cialis. After confirmation of ischemic priapism and failure of bedside management in the Emergency Department, the patient underwent operative caverno-spongiosal shunting. Postoperatively, the erection initially rebounded but gradually receded with manual compression over 48 hours. At outpatient follow-up, the patient remained flaccid without erections. This is one of the first reports of Cialis side effect of priapism. Urology. 2005.

The potential mechanisms underlying back pain and/or myalgia experienced by men taking Cialis were investigated. An integrated analysis of 10 placebo-controlled Cialis clinical trials showed that the incidence of back pain and/or myalgia was 9% in patients receiving Cialis 10 mg (N=394), 8% in patients receiving Cialis 20 mg (N=883) and 3% in placebo-treated patients. Although the mechanism of back pain and/or myalgia remains unknown, these adverse reactions appear to be self-limiting and a general effect of phosphodiesterase 5 inhibition. International Journal of Impotence Research. 2005.

Many men with erectile dysfunction (ED) have hypertension as a comorbid condition. Recent guidelines recommend thiazide diuretics as first-line therapy for hypertension. We analyzed data from 14 randomized, double-blind, placebo-controlled trials to evaluate the efficacy of Cialis 20 mg for the treatment of ED in men on thiazides. Of the 2501 patients, 163 were on concomitant thiazides (116 Cialis /47 placebo) and 159 (98%) were reported to have hypertension. The Cialis group showed a significantly greater mean baseline to endpoint improvement on all efficacy outcome measures compared to placebo-treated patients regardless of concomitant thiazide use. More importantly, the responses to Cialis were similar regardless of concomitant thiazide use. Additionally, responses to Cialis were comparable between thiazide and nonthiazide users regardless of baseline ED severity. International Journal of Impotence Research. 2005.

The mean per-patient percentages of successful intercourse attempts for the 24-hour time point were 41%, 55%, and 67% for placebo and Cialis 10 and 20 mg, respectively; for the 36-hour time point. The most common Cialis side effects were headache, back pain, dyspepsia, and nasopharyngitis. Both 10- and 20-mg Cialis improved erectile function for up to 36 hours postdosing in men with ED of varied severity. Journal of Andrology. 2005.

Cialis and Heart
Since the introduction of the first PDE5 inhibitor, Viagra, in 1998, and subsequent impotence drugs such as Levitra and Cialis, there has been concern about the side effects of these agents on the heart and their safety in patients with cardiovascular disease. Since Cialis causes vasodilation, it has blood pressure lowering ability. These Cialis side effects are usually mild and produce few symptoms. When combined with the nitric oxide donor nitroglycerine, however, blood pressure drops may be profound and life threatening. Cialis is contraindicated with nitrates.

Cialis effective for erectile dysfunction help in men with spinal cord injury
Nearly 85 percent of men with spinal cord injury given Cialis to be used as needed for a 12 week period had improvement in erections. The most common Cialis side effects were headache and urinary tract infection. Just one in four men with a spinal cord injury can achieve erections adequate for intercourse on their own. Cialis is effective for a longer period of time than Viagra and Levitra, and unlike the shorter-acting drugs, it does not interact with fatty foods, Giuliano and colleagues note. Archives of Neurology, 2007.

Cialis in China
April 2007 - Eli Lilly & Co., maker of impotence drug Cialis, hopes that Chinese couples who might resort to traditional aphrodisiacs to resolve sexual problems will seek marital bliss with its own drug remedy. Eli Lilly & Co. launched a marketing campaign for Cialis in the world's most populous country with the release of a survey showing that 45 percent of middle-aged Chinese couples had experienced erectile dysfunction problems. Since only one third of those couples had thought about seeking treatment, Eli Lilly believes that efforts to boost awareness of the problem would increase sales of Cialis, whose long-lasting effects have given it the nickname "the weekender." Cialis, which has been distributed to 5,000 Chinese pharmacies this month, is effective for up to 36 hours, longer than rival drugs on the market, according to Eli Lilly. Erectile dysfunction has historically been treated in China with traditional medicines containing herbs or animal parts such as tiger penis and rhinoceros horns. Cialis, although growing faster globally than Viagra, still lags its rival, which was launched in China by Pfizer, the world's largest drugmaker, in 2000. Levitra, an impotence drug developed jointly by Bayer AG, GlaxoSmithKline Plc and Schering-Plough Corp., is also available in China. Worldwide sales of Lilly's Cialis jumped 30 percent to $971 million.

Q. I just thought I would share my experiences with Passion Rx. Over two months ago, I chanced upon this sexual enhancing product. I was impressed by its list of ingredients, including maca, tribulus, muira puama, and yohimbe bark, and many others. Until this time, I have been dependent on Cialis - there was no way I could perform without it. Sometimes, even with Cialis, I had to have the greatest concentration else, I will lose it. I have been on testosterone patches and got no relief. So, I decided to take the plunge and ordered one Passion Rx with yohimbe. Around the 3rd week, I noticed that i started having spontaneous hard-ons. One night, during that week, my wife took me by surprise in the morning (I left the new pack of Cialis I just bought in my office and couldn't run downstairs before the action, so I decided to go ahead. I was surprised -- we did it. In the past, this would not have been possible, i would have lost my erection half-way.. But now I realized that I had so much libido -- the desire was strong. I decided to take the capsules for one more week. By the 4th week, I could have sex with my woman without taking the Cialis. In fact, I have used only 8 out of the 100 Cialis tabs that had arrived about 3 months ago. Interestingly, I noticed differences in how I feel even with a condom. Previously, I could not sustain an erection with a condom on, even when I take the Cialis. But now, without the Cialis and on this supplement alone, I can use a condom and still complete the act without losing it. I am so happy with your product that I reordered a second bottle and taking it now. I don't know when I would have to stop -- but realized that I can skip a couple of days and still have a long term effect. Thanks for a great product.