Daflon by Ray Sahelian, M.D.

Daflon is an oral medicine used in the treatment of venous disease, ie, chronic venous disease and hemorrhoids. Daflon is a micronized purified flavonoid fraction containing 90% diosmin and 10% flavonoids expressed as Hesperidin.

Daflon for venous leg ulcer
Daflon 500 mg and venous leg ulcer: new results from a meta-analysis.
Angiology. 2005 Sep-Oct;56 Suppl 1:S33-9. Smith PC. Department of Surgery, UCL Medical School, The Middlesex Hospital, London, UK.
The objective of this study was to assess the effect of oral treatment with Daflon 500 mg (micronized purified flavonoid fraction [MPFF]) on leg ulcer healing. This study was conducte. Five prospective, randomized, controlled studies in which 723 patients with venous ulcers were treated between 1996 and 2001 were identified. Conventional treatment (compression and local care) in addition to Daflon 500 mg 2 tablets daily was compared with conventional treatment plus placebo in two studies (n = 309), or with conventional treatment alone in three studies (n = 414). These results confirm that venous ulcer healing is accelerated by Daflon 500 mg treatment. Daflon 500 mg might be a useful adjunct to conventional therapy in large and longstanding ulcers that might be expected to heal slowly.

Daflon for hemorrhoids
Daflon for hemorrhoids: a prospective, multi-centre observational study.
Surgeon. 2004 Dec;2(6):335-8, 361. Meshikhes AW. Department of Surgery, Dammam Central Hospital, Dammam, Eastern Province, Saudi Arabia.
Daflon, a phlebotropic agent, is of proven efficacy in the treatment of various venous disorders. Although Daflon has been tried in the treatment of hemorrhoids, its efficacy in alleviating various haemorrhoidal symptoms has not been assessed properly. The aim of this study was to confirm the efficacy of Daflon in the treatment of haemorrhoidal symptoms. Two hundred and sixty eight patients presenting with hemorrhoids were recruited. This was a multicentre non-randomised observational study with no placebo arm. After establishing the extent of their symptoms and determining the position, size and degree of haemorrhoids by proctoscopy, all patients were started on Daflon, four tablets per day, in two divided doses for four weeks. Patients were seen weekly during the study period and carefully questioned as regard to symptoms, and a proctoscopy was carried out. There was a statistically significant improvement (p<0.001) in all haemorrhoidal symptoms (pain, heaviness, bleeding, pruritus and anal discharge) and in the proctoscopic appearance of the 'piles,' comparing baseline visit findings with the last visit four weeks after treatment with Daflon. Daflon has been shown to be effective in alleviating (variable degree) haemorrhoidal symptoms and improving the proctoscopic appearance of hemorrhoids. Therefore, it should be considered initially for patients presenting with haemorrhoidal symptoms.

Daflon emails
Q. Hello, I'm from Florida USA. I'm looking for a medicine called Daflon. I been looking everywere here in Florida but no one knows that medicine.
   A. Hi, we are not aware of it being sold in the US, but we have not looked extensively.