Endometrial cancer alternative and natural treatment and prevention
September 6 2016 by
Ray Sahelian, M.D.

Endometrial cancer is the most common female gynecologic cancer in the United States. Obesity and excessive and prolonged exposure of the endometrium to estrogens unopposed by progesterone are well-established risk factors for endometrial cancer.

Risk factors
Endometrial cancer arises in the lining of the uterus. Some risk factors have been established -- including older age, obesity and factors that expose women to more estrogen, such as late menopause and estrogen therapy after menopause.

Older women who drink lots of soda and other sugary beverages may be at higher risk, Cancer Epidemiology, Biomarkers & Prevention, news release, Nov. 22, 2013.

J Cancer. 2014. Endometrial cancer incidence in breast cancer patients correlating with age and duration of tamoxifen use: a population based study. To the best of our knowledge, this is the largest population based study that shows in patients with breast cancer, tamoxifen use for more than three years or patients older than 35 years was associated with a significantly increased risk for developing endometrial cancer.

Bull Cancer. 2015. Environmental and genetic risk factors for endometrial carcinoma. This cancer is hormone-dependent and endogenous (reproductive factors) or exogenous (oral combined contraceptives, hormone replacement therapy) causes of exposition to estrogens are the major environmental risk factors for both types of endometrial cancers: type I or well-differentiated endometrioid adenocarcinomas; and type II including all other histological types: papillary serous adenocarcinomas, clear cell adenocarcinomas and carcinosarcomas, also known as malignant mixed Mullerian tumor, MMMT. Obesity, diabetes mellitus and adjuvant treatment of breast cancer with tamoxifen are also associated with an increased risk of endometrial cancer. Genetic factors may also be implicated in the pathogenesis of endometrial cancer either as "minor genetic factors" (susceptibility factors), which remain largely unknown and are responsible for the increased observed risk in relatives of women affected with endometrial cancer; or as major genetic factors responsible for hereditary forms and namely for Lynch syndrome whose genetic transmission is of autosomic dominant type.

Dietary fiber and endometrial cancer
Dietary fiber has been shown to beneficially reduce estrogen concentrations and prevent obesity. Increasing dietary fiber may slightly reduce the risk for endometrial cancer.

Tea and coffee
Women who drink coffee and tea each day may have a lower risk of endometrial cancer. Coffee drinking seems to particularly protect overweight and obese women, according to Dr. Emilie Friberg, at the Karolinska Intstituet in Stockholm, Sweden. Coffee may affect blood sugar, fat cells, and estrogen, all of which play a role in endometrial cancer.

Polyphenols found in tea may have a tumor-shrinking effect, but results focusing on endometrial cancer haven't shown a clear benefit. Researchers from the National Shanghai Center for New Drug Safety Evaluation and Research in China analyzed several published studies looking at the role of green and black tea in the prevention of endometrial cancer. An increase in tea consumption of two cups daily was associated with a 25-percent reduced risk of developing endometrial cancer. The association was significant for green tea but not for black tea. There was also a protective effect shown in the Chinese and Japanese studies but not the American studies. The researchers cautioned that the risk reduction seen in Asian studies but not the American studies may be the result of some other unexamined factor, such as diet, lifestyle or genetic differences. For example, American tea drinkers tend to drink black tea while most of tea drinkers in China and Japan drink green tea. American Journal of Obstetrics and Gynecology, 2009.

Prevalence
Endometrial cancer - which forms in the lining of the uterus - is the fourth most common cancer in American women. The National Cancer Institute says there are 42,000 new cases in the United States each year, and nearly 7,800 deaths.

Endometrial cancer
My mother (68) has cancer (primary endometrial-stage IIIA) and is on chemo. Through your website and many books she is taking a group of supplements herbs that are making such a difference in how she is responding to and handling the chemo. Her Dr. has approved them all. Hopeless situation is now having good reports. You should be thanked for the help and good information you have supplied.

Medications that may reduce the risk
Bisphosphonates, which are drugs that treat bone loss, may lower the risk of endometrial cancer. A study found that women taking the drugs had about half the risk of endometrial cancer compared to women who don't take the drugs. Bisphosphonates include medications that go by brand names such as Actonel, Boniva and Fosamax. Cancer, news release, Dec. 22, 2014.