Fenugreek is a food and a spice commonly eaten in many parts of the
world, and has been used for centuries by practitioners of
Ayurvedic Herb
medicine and Traditional
Chinese Medicine.
Historically it has been used for
numerous conditions, including labor induction, aiding digestion, and as a
general tonic to improve metabolism and health.
Research in the past two decades has shown that fenugreek seeds help balance
blood sugar in diabetics. It may also have beneficial effects on triglycerides.
buy Fenugreek seed supplement, 100
Capsules, 610 mg
Fenugreek (Trigonella foenum graecum) is an annual Mediterranean and Asiatic
herb with aromatic seeds.
Supplement facts
Fenugreek seed - 1.22 g per 2 capsules
Usage: Take 2 fenugreek seed capsules daily, preferably with food or as recommended by your doctor..
Buy Fenugreek supplement
Diet Rx for better weight control
management, with fenugreek extract
This natural
appetite suppressant works without stimulants. Diet Rx has no added caffeine, ephedra, ephedrine alkaloids, synephrine, hormones, guarana, ginseng, or
stimulating amino acids.
Benefits of Diet
Rx
Decreases appetite so you eat less
Helps you maintain healthy blood sugar levels
Helps you maintain healthy cholesterol and lipid levels
Provides a variety of antioxidant from two dozen herbs and nutrients
Provides healthy fiber
Improves energy
Balances mood
Improves mental concentration and focus
Improves will power and choice of food selection
Other interesting botanicals to consider" Cinnamon herb, Gymnema Sylvestre leaves (Gumar), Nopal prickly pear cactus, American ginseng herb, fenugreek, and bitter melon.
Benefits of the plant
Breast feeding, milk production
It is okay to take fenugreek supplement while breastfeeding?
I have not come across enough information at this
time to know for certain whether it is safe during breastfeeding.
I have read that fenugreek can be taken when breast
feeding and that it increases breast milk production.
We reviewed a study of
fenugreek and breast milk production. Swafford S, Berens B. Effect of fenugreek on breast milk production. ABM News
and Views 2000: Annual meeting abstracts Sept 11-13, 2000. It
does not seem to be a peer reviewed study published in an accepted medical
journal. Fenugreek may be a galactagogue, but I would like to see at least one
or two good studies that are peer reviewed.
Is there anything I can take to increase milk supply besides fenugreek? I
have been taking 4 capsules 3x/day and have not noticed significant results.
I am currently not aware of herbs that have been proven to increase
milk production although some websites claim alfalfa, galaga and blessed or milk
thistle are helpful and historically many cultures have used local herbs,
possibly successfully. I just have not yet come across convincing research..
Medications or drugs used by doctors as galactogogues include metoclopramide,
domperidone, chlorpromazine, sulpiride, oxytocin, growth hormone, and
thyrotrophin releasing hormone. Many exert their pharmacologic effects through
interactions with dopamine receptors, resulting in increased prolactin levels
and thereby augmenting milk supply.
Colon cancer
Diosgenin, a steroid saponin of Trigonella foenum
graecum, inhibits azoxymethane-induced aberrant crypt foci formation
in F344 rats and induces apoptosis in HT-29 human colon cancer cells.
Cancer Epidemiol Biomarkers Prev. 2004.
Fenugreek is traditionally used to treat
disorders such as diabetes, high cholesterol, wounds, inflammation, and
gastrointestinal ailments. Recent studies suggest that fenugreek and its active
constituents may possess anticarcinogenic potential. We evaluated the preventive
efficacy of dietary fenugreek seed and its major steroidal saponin constituent,
diosgenin, on azoxymethane-induced rat colon carcinogenesis during initiation
and promotion stages. On the basis of these findings, the fenugreek constituent
diosgenin seems to have potential as a novel colon cancer preventive agent.
Mechanism of action of a hypoglycemic principle
isolated from fenugreek seeds.
Indian J Physiol Pharmacol. 2002.
Mechanism of action of an orally active hypoglycemic principle isolated from
water extract of seeds of Trigonella foenum graecum (fenugreek) was investigated
in alloxan induced subdiabetic and overtly diabetic rabbits of different
severities. The active principle was orally administered to the subdiabetic and
mild diabetic rabbits (five in each group) at a dose of 50 mg/kg body weight for
15 days. The fenugreek treatment produced significant attenuation of the glucose
tolerance curve and improvement in the glucose induced insulin response,
suggesting that the hypoglycemic effect may be mediated through
stimulating insulin synthesis and/or secretion from the beta pancreatic cells of Langerhans.
Effect of Trigonella foenum extract on blood glucose, blood
lipid and hemorheological properties in streptozotocin-induced diabetic rats.
Asia Pac J Clin Nutr. 2007.
Fenugreek seeds have previously been shown to have hypoglycemic and
hypocholesterolemic effects on type 1 and type 2 diabetes mellitus patients and
experimental diabetic animals. Fenugreek seed extract has now been investigated
for its effects on general properties, blood glucose and blood lipid, in experimental diabetic rats. Streptozotocin-induced
diabetic rats were administrated Fenugreek seed extract, and Metformin HCl for 6
weeks. Compared with diabetic group, rats treated with fenugreek seed extract
had an increase in body weight and a decrease in kidney /body weight. Compared
with diabetic group, rats treated fenugreek seed extract had lower blood
glucose, glycated hemoglobin, triglycerides, total cholestrol and higher
higher-density-lipoprotein-cholesterol in a dose-dependent manner . The plasma
viscosity, whole blood viscosity of high shear rate and low shear rate, erythrocyte sedimentation rate, whole blood reduction viscosity and
platelet conglutination were significantly reduced in diabetic rats treated with
high and middle doses of fenugreek seed extract, but not in those treated with
low dose of fenugreek seed extract. It may be concluded that fenugreek seed
extract can lower kidney /body weight ratio, blood glucose, blood lipid levels
and improve hemorheological properties in experimental diabetic rats following
repeated treatment for 6 weeks.
Effect of Trigonella foenum-graecum seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: a double
blind placebo controlled study.
J Assoc Physicians India 2001.
Twenty five newly diagnosed patients with
type 2 diabetes (fasting glucose < 200 mg/dl) were randomly divided into two groups.
Group I received 1 gm/day hydroalcoholic extract of fenugreek seeds and Group II
received usual care (dietary control, exercise) and placebo capsules for two
months. Adjunct use of fenugreek seeds improves glycemic control and
decreases insulin resistance in mild type-2 diabetic patients. Fenugreek also
has a favorable
effect on hypertriglyceridemia.
Effect of fenugreek seeds on the fasting blood glucose level in the
streptozotocin induced diabetic rats.
Mymensingh Med Journal. 2004.
In this experiment defatted Trigonella foenum seeds has been used as the antidiabetogenic herbal medicine. The experiment was
carried out in Bangabandhu Sheikh Mujib Medical University and BIRDEM from 1996
to 1998 on a total of 58 Long Evans rats of either sex. They were 50-60 days
young rats with average body weight 72-174 gm. Among the total, 10 rats were
treated with only vehicle called as non-diabetic control rats, 48 rats were
treated with Streptozotocin at a dose of 90mg in 1ml of citrate buffer
solution per kg body weight, among which 20 were diabetics. Ten (1 died, 1
escaped) diabetic rats were again treated with fenugreek called as
Fenugreek-treated diabetic rats and the rest 10 diabetic rats were called as
diabetic control rats. The change in the mean fasting blood glucose level
in different groups of rat from day 5 from streptozotocin injection were higher
in diabetic control group and in fenugreek-treated diabetic group than in non
diabetic control group. From this experiment it may be concluded that fenugreek
decreases the fasting blood glucose level considerably by improving diabetes mellitus.
Lipid lowering
Supplementation of fenugreek leaves lower lipid profile in
streptozotocin-induced diabetic rats.
Our results show that blood glucose and serum and
tissue lipids were elevated in STZ-induced diabetic rats. Supplementation of
fenugreek leaves lowered the lipid profiles.
J Med Food. 2004.
Liver protection due to alcohol
excess
Protective effect of fenugreek (Trigonella
foenum graecum) seeds in experimental ethanol toxicity.
Phytother Res. 2003.
The study investigates the effect of aqueous extract of fenugreek seeds on lipid peroxidation
and antioxidant status in experimental ethanol toxicity in rats. Ethanol feeding
for 60 days resulted in significant increases in the activities of serum aspartate transaminase, alanine transaminase and alkaline phosphatase. The
levels of serum lipid hydroperoxides and thiobarbituric acid reactive substances
in liver and brain were also significantly elevated. The fenugeek seeds exhibited appreciable antioxidant property
in vitro which was comparable with that of reduced glutathione and alpha-tocopherol.
Further, histopathological examination of liver and brain revealed that, aqueous
extract of fenugreek seeds could offer a significant protection against ethanol
toxicity.
Safety of fenugreek and side effects
As a commonly eaten food, fenugreek is generally
regarded as safe. The only common side effect is mild gastrointestinal distress
when it is taken in high doses. Animal studies have found it to be essentially
non-toxic.
Genotoxicity testing of a fenugreek extract.
Food Chem Toxicol. 2004.
Rich in protein, fenugreek seeds contain the unique major free amino
acid 4-hydroxyisoleucine (4-OH-Ile), which has been characterized as one of the
active ingredients for blood glucose control. As part of a safety evaluation of novel ingredients for use in blood
glucose control, the potential genotoxicity of a fenugreek seed extract,
containing a minimum of 40% 4-OH-ILE, was evaluated using the standard battery
of tests (reverse mutation assay; mouse lymphoma forward mutation assay; mouse
micronucleus assay) recommended by US Food and Drug Administration for
food ingredients. Fenugreek extract was determined not to be genotoxic under the conditions of
the tested genetic toxicity battery.
Fenugreek dosage
Fenugreek capsules typically
contain about 600 mg. A typical dosage is about one to two grams two times a day with
breakfast and lunch. Fenugreek tea is also available.
Additional benefits
Studies in rodents indicate that fenugreek has
immune stimulating,
antioxidant and anti-tumor properties, and protects the liver against
alcohol toxicity.
Administration of
fenugreek seed extract with ethanol to rats prevented the enzymatic leakage and
the rise in lipid peroxidation. The seeds exhibited appreciable antioxidant
property in vitro which was comparable with that of reduced glutathione and
vitamin E. Further, examination of liver and brain revealed that, extract of
fenugreek seeds could offer a significant protection against ethanol toxicity.
It also has anti-
ulcer properties.
Fenugreek extract
sold by herb and ingredient suppliers
Fenugreek herb is sold as plain powder and in various extract potencies
including a 2 to 1 extract and a 4 to 1 extract.
Gencor Announces Study Results
2009, press release
A new human clinical study was recently completed in Australia on
Testofen, Gencor's proprietary extract of fenugreek, to evaluate its effect on
libido in healthy men. The randomized, double blind placebo study tested sexual
function, performance, and libido levels in 60 healthy males aged between 21 and
50 years over a 6 week period. Results showed Testofen produced a positive
change in all parameters of libido, including sexual cognition, sexual arousal,
sexual experience and orgasm. The effect may be a result of interaction with
testosterone via alpha-5 reductase activity. A presentation of this study was
made at SupplySide West in a VendorWorks seminar on November 13, 2009, by Ms. Amanda Rao, Director of Applied Science and Nutrition Pty. Ltd.,
the CRO that conducted the study. Ms. Amanda Rao has degree and postgraduate
qualifications in science and over 15 years experience in the natural medicine
industry in Australia, including product development, regulatory affairs,
manufacture and education.
Questions
I am a fan of Dr. Sahelian's website and use it as a
reference when I am considering natural substances over prescription drugs. I
was looking at your listing for fenugreek when I noticed a reference for
Testofen. When I looked at the ingredients for that product, I noticed that the
majority active herbal ingredient was safed musli which has a traditional use in
Indian medicine for sexual dysfunction. I have not see much reference to
fenugreek as a sexual aid. The proprietary blend of Testofen includes ginseng
and b-vitamins also. I am curious about fengreek's role in this topic so I am
hoping your site might address that at some point. I do know Dr Sahelian is
affiliated with some of the products mentioned on the site but I really
appreciate the fact-based answers and reviews of the various herbal remedies and
the medical viewpoints as to dosage, use, limits and side effects. This is
unique on the web. It's so hard to get unbiased information on alternative
remedies on the internet.
As far as I know, Testofen is a fenugreek extract, perhaps
there is a product that includes this extract with the other herbs and nutrients
that you mention?
I came across a web site promoting a standardized
form of fenugreek called Testofen. It said those given 600 mg a day had a great increase in free testosterone levels
compared to the placebo group. Is Testofen a good thing to take for health?
The human body is very complicated and just looking at levels of
one hormone tells us very little regarding the long term benefit of Testofen or
any supplement that increases testosterone levels. Increasing testosterone
levels through this fenugreek extract may or may not be a healthy thing to do
until we have a few human trials published.