Gymnema sylvestre grows in South-east Asia.
Its therapeutic role in relation to diabetes mellitus, rheumatic arthritis and gout have been well known for a long
time. Extracts of this plant are widely used in Australian,
Japananese, Vietnamese and Indian folk medicine. However, gymnema is best known for its benefits in
diabetes. Gymnema helps
support healthy
blood sugar levels. Gymnema sylvestre contains compounds known as gymnemic acids and tritepenoid
saponins, gymnemasins A, B, C and D.
Gymnema sylvestre leaves
have antibacterial compounds. Anti-allergic, antiviral, lipid lowering and other
effects are also reported. Rodent studies indicate that gymnema may have the
capacity to maintain healthy
cholesterol and triglyceride levels.
If you would like to eat less and have better blood cholesterol and blood sugar
control, consider Diet Rx appetite suppressant. See below for details.
What's in Gymnema Sylvestre?
Gymnema contains a number of saponins, and flavonoid compounds including
kaempferol and quercetin.
Gymnema Safety
A one year study on rodents given gymnema did not show any toxicity.
Gymnema Sylvestre extract, 260 mg, 120 Tablets -
Source Naturals

Gymnema Sylvestre extract may help to maintain healthy blood sugar levels when
used as part of your diet. Gymnema has been used traditionally in India for
centuries and has been shown in research to support healthy glucose metabolism
by mediation of insulin release and activity and enhancement of healthy
pancreatic function. Source Naturals Gymnema Sylvestre extract is standardized
to 25% gymnemic acids, the same concentration used in clinical research.
Gymnema Sylvestre extract
Supplement Facts:
Serving Size: 1 Tablet
Gymnema Leaf Extract 25% - 260 mg
(Yielding 65 mg Gymnemic Acids)
Suggested Use: 2 gymnema tablets daily. Take 1 tablet after breakfast, and 1 after
dinner, or as recommended by your health care professional .
* Gymnema sylvestre daily value not established
Cinnamon 6 - 750 mg Cinnamon is one of the oldest remedies used in traditional
Chinese herbalism. Recent studies show cinnamon (Cinnamomum aromaticum) may
support healthy blood sugar levels when used as part of your diet, by activating
insulin and glucose transport and improving glucose metabolism. Additional herbs involved in sugar management include gymnema,
prickly pear, fenugreek, and bitter melon. Cinnamon 6 Supplement Facts: Amount Per Serving: * Daily values not established. All the herbs used in this product are either organic, wild
harvested, non-fumigated, non-irradiated, pesticide free and/or non-genetically
altered.
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Diet Rx for better blood sugar, cholesterol, and weight
control management
This natural
appetite suppressant works without stimulants. Diet Rx has no added caffeine, ephedra, ephedrine alkaloids, synephrine, hormones, guarana, ginseng, or
stimulating amino acids.
Benefits of Diet Rx
All
natural appetite suppressant, decreases appetite so you eat less
Helps you maintain healthy blood sugar levels
Helps you maintain healthy cholesterol and lipid levels
Provides a variety of antioxidant from two dozen herbs and nutrients
Provides healthy fiber
Improves energy
Balances mood
Improves mental concentration and focus
Improves will power and choice of food selection
243 Tablets - Veggie caps
Herbal Promise

Serving Size: 9 Tablets
Servings Per Container: 27
Calories 10
Carbohydrate 3 g
Dietary fiber 2 g
Chromium picolinate - 450 mcg
(375% daily value)
Proprietary blend 6750 mg:
Cinnamon , Gymnema
Sylvestre leaves (Gumar), Nopal (prickly
pear), American ginseng,
fenugreek, and bitter
melon. *
Suggested Use: Take 1 - 3 cinnamon 6 tablets 2 to 3 times daily, with breakfast,
lunch, and if needed dinner, or as recommended by your healthcare professional.
Take 3 days off each month.
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Supplement Research Update newsletter. Twice a
month we email a brief abstract of several studies on various supplements and
natural medicine topics - including gymnema sylvestre - and their practical
interpretation by Ray Sahelian, M.D.
Gymnema Sylvestre Research Update
Gymnema sylvestre leaf extract: a 52-week dietary toxicity study in
Wistar rats
Center for Biological Safety and Research, National
Institute of Health Sciences: 1-18-1, Kamiyoga, Setagaya-ku, Tokyo 158-8501,
Japan.
A 52-week study of oral-repeated-dose toxicity for the extraction powder of
Gymnema sylvestre, Indian-native genus, Metaplexis japonica, was conducted in
both genders of Wistar rats. The rats were administered a graded dose of Gymnema sylvestre at 0.01, 0.10 and 1.00% of basal powder diet, along with a group fed solely
with the basal powder diet without gymnema, for 52 weeks. General conditions
were recorded daily. Body weights and food consumptions were recorded weekly up
to 12 weeks, and thereafter at longer intervals. At 26 weeks, for an
intermediate examination, and 52 weeks, for the final examination, animals were
subjected to hematology, serum chemistry, and pathological examination. None of
the animals died in the period up to 52 weeks. No exposure-related changes in
body-weight, in the food consumption, in the hematological examinations, or in
the serum biochemical examinations were recognized. No histopathological
alterations were seen. Thus, it was concluded that there was no toxic effect in
rats treated with gymnema at up to 1.00% in the diet for 52 weeks. The
no-observable-effect level from this study is 1.00% gymnema sylvestre, i.e., 504
mg/kg/day for male and 563 mg/kg/day for female as mean daily intake, for 52
weeks.
Effect of administration with the extract of Gymnema sylvestre R. Br
leaves on lipid metabolism in rats.
Biol Pharm Bull. 2001 Jun;24(6):713-7.
Extract of Gymnema sylvestre R. Br leaves was orally administered once a
day to rats fed a high fat diet or normal fat diet for 3 weeks to investigate
its influence on lipid metabolism. As a result, Gymnema sylvestre did not influence body weight
gain or feed intake in both diet groups during the experimental period. The
apparent fat digestibility was significantly decreased by
Gymnema sylvestre in both diet groups
for the last 2 weeks of the experimental period, though not the apparent protein
digestibility. In addition, the excretion of neutral sterols and acid steroids
into feces was increased by
Gymnema sylvestre
in both diet groups. Furthermore,
Gymnema sylvestre decreased
the total cholesterol and triglyceride levels in serum. On the other hand, blood
lecithin-cholesterol acyltransferase (LCAT) activity was increased by
Gymnema sylvestre.
Moreover, it was suggested that
Gymnema sylvestre
influenced cecal fermentation and that
propionic acid and acetic acid contents in cecum were significantly increased by
Gymnema. Consequently, it was suggested that
gymnema improved serum cholesterol and
triglyceride levels through influence over a wide range of lipid metabolism in
rats.
Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients.