Helicidum in plant
October 22 2015
As of 2015 I am not aware of any human studies as a supplement.
Helicidum, formaldehydephenlyl-O-Beta-d-pyranosyl alloside, is one of the primary components from fruits of Helicid hilagirica Beed.
Scientists are attempting to extract Helicidum from Helicid hilagirica Beed herb at a concentration of 95%.
Arzneimittelforschung. 2007. Bioequivalence of two tablet
formulations of helicidum administered in single dose to healthy Chinese
volunteers. In this 2 x 2, randomized, crossover bioequivalence study, two
tablet preparations of helicidum were compared in 20 healthy Chinese male
subjects. The drug was given in a single dose of three tablets (75 mg) and blood
samples were withdrawn during 12 h after drug administration. Helicidum was
separated and analyzed using a validated liquid chromatography-mass spectrum
method. The pharmacokinetic parameters were determined from the plasma
concentration-time profiles of both formulations. The primary calculated
pharmacokinetic parameters were compared statistically to evaluate
bioequivalence between the two preparations, using various statistical methods.
The analysis of variance (ANOVA) did not show any significant difference between
the two formulations and 90% confidence intervals fell within the acceptable
range (80-120%) for bioequivalence. Based on these statistical inferences it can
be concluded that the two tablet preparations of helicidum are likely to be