Henoch-Schönlein purpura causes the blood vessels in the skin to get inflamed (irritated and swollen). This inflammation is called vasculitis. It can also affect blood vessels in the bowel and the kidneys. When the blood vessels in the skin get inflamed, they can bleed, causing a rash that is called purpura. The intestines and the kidneys may also bleed.
Fish Oil for Henoch Schonlein purpura
Managing Henoch-Schonlein purpura in children with fish oil and ACE inhibitor therapy.
Nephrology (Carlton). 2004. Department of Pediatrics, Steele Memorial Children's Research, University of Arizona, Tucson, Arizona
Henoch-Schonlein purpura is a vasculitic syndrome with palpable purpura and renal involvement. The treatment for Henoch-Schonlein purpura with persistent renal disease remains controversial. The kidney biopsy in Henoch-Schonlein purpura shows IgA deposits and fish-oil therapy has proven to be promising in halting the progression of IgA nephropathy. Five children with biopsy-proven HSP with repeated episodes of haematuria and proteinuria were treated with fish oil (1 g orally twice daily). In three of the five patients an angiotensin-converting enzyme inhibitor (ACEI) was added for hypertension. The mean duration of follow up after starting fish-oil therapy was 49.2 weeks. The protein excretion rate prior to starting fish oil was 1041 mg/day and on the last follow-up visit the rate had decreased to 104 mg/day. The average blood pressure (BP) prior to therapy was 135/82. On the last follow-up visit the average BP off ACEI had decreased to 100/54 (P <0.05). After a year of follow up serum creatinine and glomerular filtration rates have remained stable at 51.2 micromol/L and 128 mL/min/1.7 m2, respectively. This is the first report of abatement of Henoch-Schonlein purpura with fish oil and ACEI in children. There is a need for randomized prospective trials to confirm this observation.
Aloe Vera Cause
Henoch-Schonlein purpura associated with Aloe vera administration.
Eur J Intern Med. 2005.
Henoch-Schonlein purpura (HSP) is a systemic vasculitis that occurs most often in children and rarely follows exposure to drugs or other environmental factors. Aloe is one of the most widely used traditional remedies and has been associated with gastrointestinal and renal complications. We report a case of HSP in an adult patient who had previously received the herb Aloe vera.
Asia Pac Allergy. 2014. Age of onset as a risk factor of renal involvement in Henoch-Schönlein purpura. Renal involvement in children with HSP is more common in age group 11 to 15 years old.
Q. I am writing to you in regards to my daughter who is diagnosed with Henoch Schonlein purpura. She is 23 yrs old I have reached ever where possible that I can think of. Is there any other possible places you could suggest to look. If there are any new information on Henoch Schonlein purpura could you please e-mail them to me.
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