Full Spectrum Horse Chestnut, 300 mg
Planetary Formulas

Full Spectrum Horse Chestnut delivers a minimum of 20% aescin, the primary
extract in horse chestnut for assuring potency.
To insure a healthy vascular system, increase
dietary intake of flavonoid-rich foods such as vegetables, onions,
grapes and blueberries. Avoid excessive periods of standing or sitting,
and exercise regularly.
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Horse Chestnut
Supplement Facts:
Calcium 55 mg - 6% DV
Horse Chestnut Seed Extract 300 mg*
Standardized to 20% Aescin
Yielding 60 mg Aescin
Suggested Use: One horse chestnut tablet, two times daily between meals, or as
recommended by your health care professional.
* Horse Chestnut daily value not established
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Research Update newsletter. Once or twice a month we email a brief abstract of
several studies on various supplements and natural medicine topics -
including horse chestnut - and
their practical interpretation by
Ray Sahelian, M.D.
What's in Horse Chestnut Extract?
Horse chestnut seed extract contains beta-aescin and many
flavonoids.
Varicose vein
information
Diseases of the venous system are widespread disorders sometimes associated with modern
civilization and are among the major concerns of social and occupational medicine. Compression stocking therapy and horse chestnut seed extract therapy are
alternative therapies for patients with edema resulting from
chronic venous insufficiency.
Simple genetics may explain why some people get varicose veins, the
unsightly, painful bulges that appear on the legs when blood pools in the
veins. Researchers based in Scotland report that people whose mother,
father, brother or sister has varicose veins are more likely than those
with no family history to develop the condition. There is conflicting
reports as to whether there is a relationship
between varicose vein risk and certain lifestyle factors such as diet, smoking and
mobility at work. Men and women who are relatively tall and women who were obese were also more likely
to show signs of varicose veins than others.
Horse Chestnut Extract Research
The aim of this study was to compare the efficacy of Venostasin (600 mg of horse chestnut
seed extract) and 360 mg of Pycnogenol (French maritime pine bark extract) in the
treatment of chronic venous insufficiency (CVI). Pycnogenol was found to be more efficacious than Venostasin for
the treatment of CVI. Those taking the pycnogenol had a reduction in leg pain and
swelling.
Horse Chestnut
Research Update
Horse chestnut seed extract for chronic venous insufficiency.
Cochrane Database Syst Rev. 2004;(2):CD003230.
Conservative therapy of chronic venous insufficiency (CVI) consists largely
of compression treatment. However, this often causes discomfort and has been
associated with poor compliance. Therefore, oral drug treatment is an attractive
alternative. To review the evidence from rigorous clinical trials assessing the
efficacy and safety of oral horse chestnut seed extract versus placebo, or other
treatments for CVI. SEARCH STRATEGY: Randomised controlled trials (RCTs) of
horse chestnut seed extract for chronic venous insufficiency. Manufacturers
of horse chestnut seed extract preparations and experts on the subject were
contacted for published and unpublished material. SELECTION CRITERIA: Studies were
included if they compared oral horse chestnut seed extract mono-preparations
with placebo, or other treatments, in patients with CVI. Trials assessing horse
chestnut seed extract as one of several active components in a combination
preparation, or as a part of a combination treatment, were excluded. RESULTS:
Overall, there appeared to be an improvement in CVI related signs and symptoms
with horse chestnut seed extract compared with placebo. Leg pain was assessed in
seven placebo-controlled trials. Six reported a significant reduction of leg
pain in the horse chestnut seed extract groups compared with the placebo groups,
while another reported a statistically significant improvement compared with
baseline. Meta-analysis of five trials (n = 289) suggested a significant
reduction in favor of horse chestnut seed extract compared with placebo. One
trial indicated that horse chestnut seed extract may be as effective as
compression stockings at reducing leg volume. Adverse events were usually mild
and infrequent. CONCLUSIONS: The evidence presented implies that horse chestnut
seed extract is an efficacious and safe short-term treatment for CVI. However,
several caveats exist and more rigorous studies are required to assess the efficacy
of this treatment option.
Horse chestnut extract :a multidisciplinary
clinical review.
J Herb Pharmcother. 2002;2(1):71-85.
Horse chestnut seed extract is widely used in Europe for the management of
chronic venous insufficiency (CVI). Although traditionally recommended for a
variety of medical conditions, CVI is the only indication for which there is
strong supportive scientific evidence. Review of the literature reveals 14
randomized controlled trials, of which seven are methodologically of high
quality, albeit limited by small sample sizes and short durations. These studies
support the superiority of horse chestnut over placebo, and suggest equivalence
to compression stockings and to oral oxerutins. In the future, a longer and
adequately powered randomized trial is warranted to compare horse chestnut to
standard of care, and to further assess safety and long-term efficacy. There are
no data to suggest that horse chestnut flower, raw seed, branch bark, or leaf
are effective for any indication, and it is recommended that these products not
be used, as they are known to be toxic when ingested.
Rational therapy of chronic venous insufficiency --chances and
limits of the therapeutic use of horse chestnut seeds extract.
BMC Cardiovasc Disord. 2001;1(1):5. Epub 2001 Dec 07.
We report two clinical studies, one already published,
performed in patients with early and advanced chronic venous insufficiency (CVI).
In both, compression therapy and oral therapy with horse chestnut seeds extracts were compared to placebo. RESULTS: The published study in early CVI
(Grade I) showed horse-chestnut and compression to be superior to placebo and to be
equivalent to each other in reducing lower leg volume, a measure for edema. In
the study, in advanced CVI (Grade II and IIIa), compression appeared to be
superior to placebo, whereas horse-chestnut was not. Horse-chestnut fared better in Grade II than in
Grade IIIa patients. These results are discussed in the light of data from an in
vitro model, where horse-chestnut has been able to close the intercellular gaps in the
venular endothelium. Not fully specified factors lead to an opening of these
gaps, resulting in edema as well as in local coagulation and thrombosis. The
subsequent inflammation keeps these gaps open and initiates and maintains a
chronic disease process, which may be the starting point of CVI. CONCLUSION: Due
to its ability to close the venular endothelial gaps, horse chestnut seems to be a
suitable and protecting therapy during the early stages of CVI. In later more
severe stages compression therapy is indicated. Taking into account the observed
negative impact of compression on quality of life, pharmacological CVI therapy
should start early to avoid progress and to spare patients compression therapy.
Horse Chest Nut Extract 20% Aescin
Horse Chestnut extract emails
Q. I noticed that products that are made to treat spider-veins
usually contain either horse chestnut (capsules or creams), or vitamin k
(creams for topical use). Horse chestnut is a blood thinner, whereas
vitamin k is essential for blood clotting. It therefore seems to me that
the effects of these two supplements might be contradictory but still they
are both used for the same purpose. I'd like to ask how is this possible.
A. This is a good question. Spider veins are unsightly,
and sometimes uncomfortable, enlargement of smaller veins closest to the
skin surface, and appear in clusters of red, blue or purple veins. Most
often spider veins occur on the legs but can also be seen on the face and
elsewhere on the body. Horse chestnut works by improving the capillary
wall and integrity of the vascular system, it may have blood thinning
ability but it also has the ability to protect the strength of the veins.
Vitamin K supplements help to clot the blood better in those who are
deficient in the vitamin, which is not that common. We don't know
the rational of adding vitamin
K to horse chestnut since most people don't need it. Perhaps you
could ask the company that formulates it and they can provide their
thoughts on this and may provide an answer that we are not aware of.
Horse Chestnut Extract information