Horsetail is an herb that contains high concentrations of silicic acid and other silicates. Horsetail also contains several minerals including potassium, manganese, along with flavonoids such as apigenin, luteolin and quercetin.
J Toxicol Pathol. 2010. Evaluation of the Subchronic Toxicity of Dietary Administered Equisetum arvense in F344 Rats. Equisetum arvense, commonly known as the field horsetail, has potential as a new functional food ingredient. However, little information is available on its side effects, and the general toxicity of Equisetum arvense has yet to be examined in detail. In the present study, we evaluated the influence of administration in diet at doses of 0, 0.3, 1 and 3% for 13 weeks in male and female F344 rats. No toxicity was detected with reference to clinical signs, body weight, urinalysis, hematology and serum biochemistry data and organ weights. Microscopic examination revealed no histopathological lesions associated with treatment. In conclusion, the no-observed-adverse-effect level (NOAEL) for Equisetum arvense was determined to be greater than 3% in both sexes of F344 rat (males and females: >1.79 g/kg BW/day and >1.85 g/kg BW/day, respectively) under the conditions of the present study.
Horsetail Plant Research
Hepatoprotective and free radical scavenging activities of phenolic petrosins and flavonoids isolated from .
J Ethnopharmacol. 2004.
Hepatoprotective activity-guided fractionation of the MeOH extract of Equisetum arvense (Equisetaceae) resulted in the isolation of two phenolic petrosins, onitin (1) and onitin-9-O-glucoside (2), along with four flavonoids, apigenin (3), luteolin (4), kaempferol-3-O-glucoside, and Quercetin-3-O-glucoside. Among these, compounds 1 and 4 exhibited hepatoprotective activities on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells These results support the use of horsetail plant for the treatment of hepatitis in oriental traditional medicine.
Antinociceptive and anti-inflammatory properties of the hydroalcoholic extract of stems from Equisetum arvense L. in mice.
Pharmacol Res. 2004.
In this study, antinociceptive and anti-inflammatory effects of hydroalcoholic extract of stem from Equisetum arvense in mice were evaluated. The extract (10, 25, 50 and 100mgkg(-1), i.p.), reduced the writhing induced by acetic acid in 49, 57, 93 and 98%, respectively. In the formalin test, 50 and 100mgkg(-1) (i.p.) extract, reduced in 80 and 95% the licking activity in the first phase, but in the second phase only the latter dose diminished the licking time (35%). In both phases, naloxone failed to revert the analgesic effect of the extract. In the hot-plate test, the extract at 100 and 200mgkg(-1) does not change the latency to licking or jumping. In the carrageenan-induced paw oedema, the extract at 50mgkg(-1), reduced the paw oedema 2h (25%) and 4h (30%) after carrageenan administration. The dose of 100mgkg(-1) caused reduction of the paw oedema (29%) only 4h after carrageenan administration. These results indicate that this extract exhibits an antinociceptive effect in chemical models of nociception which is not related to the opioid system, as well as anti-inflammatory properties.
Horsetail Extract 7% Silica
Horsetail herbal supplement emails
Q. Can horsetail herb be taken the same day as ginkgo biloba?
A. As long as the dosages are low and reasonable, it should be fine.
Hair product with Horsetail
New York, NY., November 2006 According to a recent randomized, double-blind, placebo-controlled study published in the Journal of International Medical Research (November 1, 2006), Nourkrin, a natural supplement intended to promote hair regrowth, indicates that the product is effective in improving hair growth. Active ingredients in Nourkrin include a marine based extract, Vitamin C, Silica and Horsetail Extract. The clinical trial consisted of 60 volunteers of both genders, aged 18 and above, all with hair-loss problems for a period of at least one year before entering the study. The clinical trial was conducted as a randomized, double-blind, placebo-controlled study with two arms, followed by an open phase on active treatment. During the six month blinded phase, 30 participants were randomly assigned to take Nourkrin and 30 received placebo. The dosage of two tablets per day for participants below 80 kg in body weight and three tablets per day for those above 80 kg was given to both groups. In the immediately following open phase, participants who had been taking Nourkrin in the blinded phase continued with this treatment for another six months, while participants who had been in the placebo group were switched to Nourkrin for 12 months. All participants thus received treatment with Nourkrin for 12 months. 77 percent of the participants in the group receiving Nourkrin reported that they had an effect from the treatment period of six months. This result is supported by the clinical observations. The hair counting method showed an average increase of 45 percent during the study period. In the placebo group, none of the participants reported any improvements in hair growth after six months. Nourkrin is a product of Lifes2good, an Irish based company, that produces safe and natural health, beauty and lifestyle products. Lifes2good is committed to product excellence.