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Horsetail Plant Research Update
Hepatoprotective and free radical scavenging activities of phenolic petrosins
and flavonoids isolated from Equisetum arvense.
J Ethnopharmacol. 2004 Dec;95(2-3):421-4.
Hepatoprotective activity-guided fractionation of the MeOH extract of Equisetum
arvense L. (Equisetaceae) resulted in the isolation of two phenolic petrosins,
onitin (1) and onitin-9-O-glucoside (2), along with four flavonoids, apigenin
(3), luteolin (4), kaempferol-3-O-glucoside (5), and quercetin-3-O-glucoside
(6). Among these, compounds 1 and 4 exhibited hepatoprotective activities on
tacrine-induced cytotoxicity in human liver-derived Hep G2 cells These results support the use of
horsetail plant for the treatment of
hepatitis in oriental
traditional medicine.
Antinociceptive and anti-inflammatory properties of the hydroalcoholic
extract of stems from Equisetum arvense L. in mice.
Pharmacol Res. 2004 Mar;49(3):239-43.
In this study, antinociceptive and anti-inflammatory effects of hydroalcoholic
extract of stem from Equisetum arvense in mice were evaluated. The extract (10,
25, 50 and 100mgkg(-1), i.p.), reduced the writhing induced by acetic acid in
49, 57, 93 and 98%, respectively. In the formalin test, 50 and 100mgkg(-1) (i.p.)
extract, reduced in 80 and 95% the licking activity in the first phase, but in
the second phase only the latter dose diminished the licking time (35%). In both
phases, naloxone failed to revert the analgesic effect of the extract. In the
hot-plate test, the extract at 100 and 200mgkg(-1) does not change the latency
to licking or jumping. In the
carrageenan-induced paw oedema, the extract at
50mgkg(-1), reduced the paw oedema 2h (25%) and 4h (30%) after carrageenan
administration. The dose of 100mgkg(-1) caused reduction of the paw oedema (29%)
only 4h after carrageenan administration. These results indicate that this
extract exhibits an antinociceptive effect in chemical models of nociception
which is not related to the opioid system, as well as anti-inflammatory
properties.
horsetail extract - Horsetail Extract 7% Silica
Horsetail emails
Q. Can horsetail herb be taken the same day as
ginkgo biloba?
A. As long as the dosages are low and reasonable, it should be
fine.
Hair product with Horsetail
New York, NY., November 2006 According to a recent randomized,
double-blind, placebo-controlled study published in the Journal of
International Medical Research (November 1, 2006), Nourkrin, a natural
supplement intended to promote hair regrowth, indicates that the product
is effective in improving hair growth. Active ingredients in Nourkrin
include a marine based extract, Vitamin C, Silica and Horsetail Extract.
The clinical trial consisted of 60 volunteers of both genders, aged 18 and
above, all with hair-loss problems for a period of at least one year
before entering the study. The clinical trial was conducted as a
randomized, double-blind, placebo-controlled study with two arms, followed
by an open phase on active treatment. During the six month blinded phase,
30 participants were randomly assigned to take Nourkrin and 30 received
placebo. The dosage of two tablets per day for participants below 80 kg in
body weight and three tablets per day for those above 80 kg was given to
both groups. In the immediately following open phase, participants who had
been taking Nourkrin in the blinded phase continued with this treatment
for another six months, while participants who had been in the placebo
group were switched to Nourkrin for 12 months. All participants thus
received treatment with Nourkrin for 12 months. 77 percent of the
participants in the group receiving Nourkrin reported that they had an
effect from the treatment period of six months. This result is supported
by the clinical observations. The hair counting method showed an average
increase of 45 percent during the study period. In the placebo group, none
of the participants reported any improvements in hair growth after six
months. Nourkrin is a product of Lifes2good, an Irish based company, that
produces safe and natural health, beauty and lifestyle products.
Lifes2good is committed to product excellence.
Alternative medicine information