Hyssop herb Hyssopus officinalis
December 1 2016 by Ray Sahelian, M.D.

Hyssop plant (Hyssopus officinalis) has been cultivated in Central Europe for a long time. Hyssop serves not only as spice but in many countries including Hungary, it is used as a folk medicine against certain respiratory diseases.

Chemicals and substances
Hyssop contains rosmarinic and caffeic acids along with pinanones, beta-pinene, limonene, pinocamphone, and isopinocamphone.

Antioxidant
Adv Pharm Bull. 2011. Phytochemical analysis and antioxidant activity of Hyssopus officinalis L. from Iran. On the whole, the findings of the study revealed that Hyssop possesses valuable antioxidant properties for culinary and possible medicinal use.
Additional potent antioxidants include acetyl-l-carnitine pill also used for brain health,
and resveratrol found in grapes.

Blood sugar
Inhibitory effects of hyssop (Hyssopus officinalis) extracts on intestinal alpha-glucosidase activity and postprandial hyperglycemia.
J Nutr Sci Vitaminol. 2003.
It has been known that hyssop is a herb that grows in the wild and is a source of natural antioxidants. We previously reported that a-glucosidase inhibitors, from the dry leaves of hyssop, were isolated. This study examined the alpha-glucosidase inhibitory effects of hyssop extracts on intestinal carbohydrate absorption in rat everted gut sac and carbohydrate-loaded hyperglycemia in mice. In the everted gut sac experiment, 10 mM sucrose- and 5 mM maltose-treated increases in glucose concentration in the serosal compartment were inhibited in the presence of 0.5 and 1.0 mg/ mL hyssop extracts, although a 10 mM glucose-induced increase in serosal glucose was not inhibited by the extracts. Additionally, hyperglycemia in sucrose- and maltose-loaded mice was significantly suppressed at an early stage, within 30 to 60 min by oral pre-administration of 300 and 100 mg/kg hyssop extracts, respectively. These findings suggest that hyssop extracts inhibited the digestion of complex carbohydrates, but not that of absorbable monosaccharide, and might be a useful supplemental food for hyperglycemia.

  
Alpha lipoic acid can be useful for those who have high blood sugar levels.

I heard Hyssop was being used to lower blood sugar. Your article seems to say the opposite.
   We have not seen any clinical studies in humans regarding the use of hyssop for blood sugar or diabetes, hence we can't say whether hyssop herb is effective for this purpose. Actually the rat study you refer does indicate hyssop was able to be helpful in high blood sugar.

HIV
Crude extracts of dried leaves of Hyssop contain strong anti-viral and anti-HIV-1 activity.

Infection
Essential oils of sage, mint, and hyssop generally have a bacteriostatic activity.

Lung health, immunity
Exp Ther Med. 2014. Effect of Hyssopus officinalis L. on inhibiting airway inflammation and immune regulation in a chronic asthmatic mouse model. The Uygur herb, Hyssop, has been demonstrated to affect the levels of a number of cytokines in asthmatic mice, including interleukin-4, -6 and -17 and interferon-γ. Hyssop not only plays an anti-inflammatory role by inhibiting the invasion of EOS and decreasing the levels of IgE, but also affects immune regulation.

Hyssop herb caution
Very high doses of hyssop have been found to have convulsant properties, perhaps due to their content of terpene ketones pinocamphone and isopinocamphone.

Review
it's difficult to make any recommendations regarding hyssop since so little is known about its properties. See a list of herbs used in medicine.

Hyssop Plant Research
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2011.
The effect of Uygur medicine Hyssopus officinalis L on expression of T-bet, GATA-3 and STAT-3 mRNA in lung tissue of asthma rats. Hyssop probably regulates the differentiation of Th1, Th2 and Th17 on transcription level to play the role of anti-inflammatory.

Isolation of alpha-glusosidase inhibitors from hyssop.
Phytochemistry. 2004.
Alpha-Glucosidase inhibitory activity was found in aqueous methanol extracts of dried hyssop (Hyssopus officinalis) leaves. Active principles against alpha-glucosidase, prepared from rat small intestine acetone powders, were isolated and characterized.

Anise Hyssop plant information
Anise hyssop (Agastache foeniculum) is an erect, branched perennial herb and member of the mint family. Anise hyssop has a pleasant anise-like aroma. Anise hyssop has been used by North American native people as a breath-freshener, tea and as a sweetener.

Agastache rugosa is called by several common names including Korean Mint, Purple Giant Hyssop

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