Lupron medication benefit and side effects
January 2 2016 by Ray Sahelian, M.D.


Lupron is used to prepare the ovaries for stimulation with fertility medications. Lupron temporarily shuts down the messages from the brain to the pituitary gland, which then shuts down FSH and Luteinizing hormone production. Without the production of these hormones, the ovaries canít produce the necessary hormones to make eggs. When fertility medications are added Lupron allows the ovaries to grow multiple eggs and suppresses the selection process that only permits one egg a month to ovulate. It also prevents ovulation from occurring before the egg retrieval.


Lupron side effects, risk, danger

The following are some potential Lupron side effects: Headache, irritability, hot flashes, night sweats, vaginal dryness, and ovarian cyst formation.


Psychosomatics. 2013. Leuprolide-Induced Extrapyramidal Symptoms Successfully Treated With Propranolol.


How is Lupron drug administered?
Lupron Depot (leuprolide acetate for depot suspension) is a GnRH agonist. It can be administered as an intramuscular injection (into muscle), a subcutaneous injection (under the skin), as a depot injection (a shot given periodically at a doctor's office), or as an implant.



Q. I completed radiation treat for prostate cancer. I have had 4 shots of Lupron drug and skd for 4 more for the past 6 months i have had constant severe pain in both legs it hurts day and nite my local doctors are baffled as to why the pain. They prescribed Vicodin daily. It helps a little. i think it is a side effect of the Lupron drug i spent several hrs on the web researching lupron drug. 2 docs hate it  because of the side effects on men and women, another Lupron side effect is loss of muscle in the legs, I do not want another year of pain so i am stopping the Lupron drug.


Q. I read an article about Lupron medication which had your name attached to it. We have a 90 year old father, who has Lewy Body Dementia, and prostate cancer. He has been on Lupron for nearly a year. His dementia is progressing rapidly. After a series of psychiatric visits and a stay in and Alzheimers unit, my brother and I brought him home, to his house. At that point, he had been without the Lupron for about a month because of a mix up due to the different facilities. For that month, he was fairly lucid, only slightly confused and very pleasant to be around. Then on August 26, 2008 he got a one month Lupron shot. The next day, he started on a journey whereby he is nearly losing his mind. He is confused, hot, angry and out in left field somewhere. My brother and I did not want to give him that Lupron shot, but other family members insisted. My dad does not want to live. He just does as he is told. We have medical power of attorney, and want to stop the Lupron shot, since daddy is so unhappy.
   A. Lupron medication can cause cognitive side effects.