Mumps virus infection and how to treat it, by Ray Sahelian, M.D.
Mumps is an acute viral illness caused by the mumps virus. It can be as mild as a fever and swollen glands, or severe enough to cause deafness, testicular inflammation and encephalitis.
2006
Mumps made an alarming comeback in the United States in 2006. The outbreak
of mumps viral disease came despite the widespread use of a second dose of
a mumps vaccine, produced by Merck, beginning in 1990. Eighty-four percent
of the people between the ages of 18 and 24 who became ill in the outbreak
had received the second recommended dose. There were no deaths from the
mumps virus infections. But there were 6,584 cases nationwide and 85
hospitalizations, most concentrated in eight midwestern states and on
college campuses. The 2006 outbreak was the first account of a large-scale
mumps epidemic characterized by two-dose vaccine failure.
Mumps vaccine
The MMR is a 3-in-1 vaccine that protects against measles, mumps and
rubella (German measles), which is usually administered between 12 and 15
months of age and again between 4 and 6 years of age. In general
vaccination required before a child can be admitted to school.
Mumps symptoms
Mumps can give a number of symptoms which include fever, headache, muscle
aches, tiredness, and loss of appetite; followed by swelling of salivary
glands. The parotid salivary glands (which are located within your cheek,
near your jaw line, below your ears) are most frequently affected.
Mumps Vaccine
In the United States, mumps vaccine is delivered
in combination with measles and rubella vaccines. Although the two-dose strategy
ensures that a high proportion of those who are vaccinated will be immune to
mumps, the seroconversion rate after two doses of vaccine is estimated to be
88
percent.
Thus, the proportion of persons in a U.S. community who are susceptible to mumps
is greater than the proportion who are susceptible to measles, and outbreaks,
when they occur, will be larger.
Mumps Outbreak in UK
More than 50,000 cases of mumps have been identified in the United Kingdom during the past few years, and more than 2500 cases have already been identified in a U.S. outbreak this year. About half the persons affected in the U.S. outbreak had been vaccinated, and most were young adults. Although mumps is a less severe disease than measles, it does cause substantial illness, including parotitis, orchitis, and aseptic meningitis. These outbreaks demonstrate the potential for rapid dissemination of respiratory pathogens, facilitated by air travel and crowded conditions.
Outbreak in USA
More than 6,000 cases of mumps have been reported to the U.S. Centers for
Disease Control and Prevention in 2006, reinforcing the importance of the
MMR vaccine, particularly in high-risk populations, such as healthcare
workers and college students. The bulk of cases, 84 percent, came from
just 6 states. Iowa reported the most, followed by Kansas, Wisconsin,
Illinois, Nebraska, and South Dakota. The average patient age was 22 years
and 63 percent of patients were female.