Naringin is one of the citrus bioflavonoids.
The common citrus bioflavonoids include:
Apigenin -- found
in high amounts in parsley,
Thyme, and peppermint
and many other herbs including
lemon balm.
Hesperidin --
found in citrus peel and pulp -- commercial orange juice provides 444 mg/l
hesperidin
Hesperitin --
Naringenin
Naringin
Narirutin -- commercial orange juice provides 96 mg narirutin per liter
Nobiletin -- a citrus bioflavonoid isolated from tangerines
Quercetin is found
in high amounts
in onions, kale, hot peppers, and rutabagos.
Rutin
Tangeretin
Tangeritin
NADH for mind
Naringin Research Update
The hypoglycemic effects of hesperidin and naringin are partly mediated by
hepatic glucose-regulating enzymes in C57BL/KsJ-db/db mice.
J Nutr. 2004 Oct;134(10):2499-503.
Dietary antioxidant compounds such as bioflavonoids may offer some protection
against the early stage of diabetes mellitus and the development of
complications. We investigated the effect of citrus bioflavonoids on blood
glucose level, hepatic glucose-regulating enzymes activities, hepatic glycogen
concentration, and plasma insulin levels, and assessed the relations between
plasma leptin and body weight, blood glucose, and plasma insulin. The current
results suggest that hesperidin and naringin both play important roles in
preventing the progression of hyperglycemia, partly by increasing hepatic
glycolysis and glycogen concentration and/or by lowering hepatic
gluconeogenesis.
Naringin, a citrus flavonone, protects against radiation-induced
chromosome damage in mouse bone marrow.
Mutagenesis. 2003 Jul;18(4):337-43.
Free radicals are responsible for the induction of damage to the
cellular DNA that leads to the formation of chromosome aberrations.
Antioxidants are known to scavenge free radicals, thereby decreasing the
degree of such effects. Radiation is a well-known inducer of free radicals
and compounds that can scavenge free radicals may reduce radiation-induced
DNA damage. Naringin, a bioflavonoid predominant in grapefruit and other
citrus fruits, has been found to scavenge free radicals, therefore it may
also reduce radiation-induced damage. The aim of the present study was to
evaluate the radioprotective action of 2 mg/kg naringin in the bone marrow
of mice exposed to different doses of (60)Co gamma-radiation by scoring
the frequency of asymmetrical chromosomal aberrations. The irradiation of
mice resulted in a dose-dependent elevation in the frequency of aberrant
cells, acentric fragments, chromatid and chromosome breaks, dicentrics and
exchanges. All these aberrations were elevated with scoring time up to 24
h post-irradiation and declined thereafter, except chromatid breaks, which
were maximum at 12 h post-irradiation. Treatment of mice with 2 mg/kg body
wt naringin before exposure to various doses of gamma-radiation resulted
in a significant reduction in the frequencies of aberrant cells and
chromosomal aberrations like acentric fragments, chromatid and chromosome
breaks, centric rings, dicentrics and exchanges. The evaluation of free
radical scavenging activity of naringin revealed a dose-dependent
scavenging of hydroxyl, superoxide and 2,2 equal to or precedes
-diphenyl-1-picryl hydrazyl radical. Naringin at 5 microM scavenged the
2,2-azino-bis-3-ethyl benzothiazoline-6-sulphonic acid cation radical very
efficiently, where a 90% scavenging was observed. Our study demonstrates
that naringin can protect mouse bone marrow cells against
radiation-induced chromosomal damage.
Naringin questions
Q. Hi Doctor, do you know of a brand of naringin or naringenin. I’ve been
searching and can’t find anything. The amounts in some vitamin C /
bioflavinoid complexes is too little.
A. If you search google, you will find products that only contain
naringin. We can't a product that only has narigenin.
Thanks for any information you know of.
Additional links
Tongkatali.net research
Tribulusterrestrisextract.com
research
Yohimbebark.net research