Natural Health Remedies and alternatives to medications newsletter
Get a free Natural Health Remedies Newsletter by email once or
twice a month.
Click the link below and place your email address.
PhysicianFormulas.com has dozens of high quality supplements where you can also find Diet Rx, Eyesight Rx, Joint Power Rx, Mind Power Rx and Passion Rx.
Last year's Natural Healing Secrets newsletter 2016.
Natural Healing Secrets
Vol. 14, Issue 3 -- March 2017
Does eating soy increase or decrease the risk for breast cancer?
Over the years I have had many female patients tell me that
they have reduced or eliminated their intake of soy products due to their fear
that estrogen-like substances in these foods promote the growth of breast
cancer. If you google "soy danger" you will come across many articles that make
it seem that soy products are toxic for human consumption. Do not be misled by
such articles. I am not saying that soy products should become a large part of
your diet. My main point is that reasonable consumption of soy products,
especially organic, as part of a wide range of intake of foods, is safe.
Soy products are available in many forms, including the beans (in Japanese restaurants they are served as appetizers and called edamame), soy milk (buy unsweetened and add the no-calorie sweetener stevia), tofu, miso, tempeh, and soy powder (some bodybuilders take it as a form of extra protein). Many processed foods have added soy and it is a good idea, in general, to minimize intake of processed foods.
Substances in soy products
Soy foods contain substances known as isoflavones. Soybeans and soy derived products are the highest sources of isoflavones in the American diet. The two most common types of isoflavones in soy are genistein and daidzen. Isoflavones have many functions in the body and they also function as phytoestrogens.
What is a phytoestrogen?
The chemical structure of an isoflavone is similar to the hormone estrogen and that is why they are also called phytoestrogens (phyto means plant). Because of this similarity in structure, isoflavones can influence estrogen receptors on cells. The influence of phytoestrogens on estrogen receptors is still being actively investigated... and it is complicated. Many scientists now believe that phytoestrogens compete with estrogen for the same receptor sites and hence lower the risks of too much estrogen (thus potentially reducing the risk for breast cancer). On the other hand, since the body's natural level of estrogen drops during menopause, some claim that isoflavones can compensate this by binding to the same receptor, thereby easing symptoms of menopause. There is still a lot that we need to study on this topic before we can come to definitive conclusions.
Benefits versus risks
I am convinced that small or reasonable amounts of soy in the diet does not do harm. Perhaps very high amounts can cause problems. Here are summaries of two recent academic reviews:
Br J Pharmacology. October 9, 2016. Phytoestrogens are plant-derived dietary compounds with structural similarity to 17-β-estradiol (E2), the main female sex hormone. This structural similarity to estradiol allows phytoestrogens to cause anti-estrogenic effects by binding to estrogen receptors. Many beneficial health effects have been attributed to phytoestrogens, such as a lowered risk of menopausal symptoms like hot flushes and osteoporosis, reduced risks of heart disease, metabolic syndrome and type 2 diabetes, breast cancer, prostate cancer, and other cancers. In contrast to these beneficial health claims, the anti-estrogenic properties of phytoestrogens have also raised concerns since they might act as endocrine disruptors. A definitive conclusion on possible beneficial health effects of phytoestrogens versus risks cannot be made.
Nutrients. November 24, 2016. There is evidence that soyfoods reduce risk of coronary heart disease and breast and prostate cancer. Soyfoods are uniquely-rich sources of isoflavones which are classified as both phytoestrogens and selective estrogen receptor modulators. Despite the many proposed benefits, the presence of isoflavones has led to concerns that soy may exert untoward effects in some individuals. However, these concerns are based primarily on animal studies, whereas human research supports the safety and benefits of soyfoods. In support of safety is the recent conclusion of the European Food Safety Authority that isoflavones do not adversely affect the breast, thyroid or uterus of postmenopausal women.
Role in breast cancer
Because excess estrogen can promote the growth and spread of breast cancers, some physicians have warmed their female patients that eating a lot of soy foods or soy isoflavones (which can be taken as a dietary supplement) could increase the risk, or worsen the prognosis of women diagnosed with breast cancer. However, recent studies do not support this view. A recently published by scientists at Tufts University concludes that isoflavones could actually reduce the risk.
Cancer, 2017. Dietary isoflavone intake and all-cause mortality in breast cancer survivors. Soy foods possess both antiestrogenic and estrogen-like properties. It remains controversial whether women diagnosed with breast cancer should be advised to eat more or less soy foods, especially for those who receive hormone therapies as part of cancer treatment. The association of dietary intake of isoflavone, the major phytoestrogen in soy, with all-cause mortality was examined for a period of nine years in 6235 women with breast cancer enrolled in the Breast Cancer Family Registry. The results show, in this large, ethnically diverse cohort of women with breast cancer living in North America, that a higher dietary intake of isoflavone was associated with a reduced all-cause mortality.
I know there are people out there whose mind is set that soy ingestion, no matter how little, is dangerous. Based on everything that I have read and studied, I do not agree. If you like soy products do not be concerned about consuming small or reasonable amounts, preferably organic, as part of your wide variety of food intake. Chances are this will be more health promoting that harm producing.
For more information on natural ways to reduce the risk for breast cancer, see www.raysahelian.com/breastcancer.html
Natural Healing Secrets
Vol. 14, Issue 2 -- February 2017
Right after I finished medical school I began my
internship at a hospital near Philadelphia, PA. The hours were grueling
and twice a week I had to work an overnight shift. One night, around 2
AM, I was woken up to rush to a patient who had fallen down while making
her way to the bathroom. The nurse told me she suspected a stroke since
the patient had slurred speech and was disoriented. Fortunately the 77
year old patient, who had been admitted for gallbladder surgery, had not
broken any bones during her fall. She just had some bruises on her right
thigh. I did a full neurological exam and determined her symptoms were
not consistent with a stroke. I reviewed her chart and medical history.
It turned out her doctor had prescribed Xanax before bed (she was having
surgery the next morning and the doctor wanted her to have a good
night's rest without worry). I have personally tried Xanax at 0.5 mg. It
is a potent anti-anxiety medication. She was given 1 mg, twice the dose
that makes me groggy and sleepy. I occasionally take it during overseas
airplane flights, along with my personal concoction of sleep inducing
herbs, and it helps me catch a few hours of z's. I reassured the nurse
that I did not suspect anything serious and there was no reason to call
her attending doctor.
I went back to bed since I still had a full day of work coming up. Before breakfast I went up to her room for a follow up. The staff was getting ready to prep her and escort her to the operating room. I chatted with her a couple of minutes. There was no slurring or any signs of disorientation. Apparently she had never taken a sleeping pill before and did not know her doctor had prescribed it to her. Actually she did not remember much of her fall or what happened overnight.
This was my first month at the hospital and I was already starting to suspect that medication mistakes were not uncommon. Certain doctors just did not understand the fragile physical and mental state of some seniors. In last month's issue of the newsletter I shared with you my opinion on the importance of doctors, nutritionists, healers, etc., to try supplements themselves as an additional way to have a better understanding of their positive and negative effects. I feel the same way about certain medications. I think doctors should try themselves some medications that they often prescribe. For instance I think psychiatrists could get further insights into the effects of the antidepressants they prescribe if they themselves experiment with the different SSRI drugs, such as Prozac or Zoloft. If this woman's doctor had tried Xanax himself, he probably would have been more careful and prescribed 0.5 mg or even 0.25 mg instead of 1 mg. That could have still helped her sleep and take the edge off her worry but without the excessive sedation and disorientation.
Age limit on supplements? A question recently
received by email
Q. I am a 65 years old male in good health. In your opinion is there an age limit on taking herbals, hormone supplements or amino acids?
A. There is no age limit to taking dietary supplements (I have patients in their 90s take them) but the amounts required or tolerated by older individuals are not necessarily the same as that of those in their 20s to 50s. As we age there are issues with absorption, metabolism, and elimination. It is possible that absorption of certain supplements may not be as good as we age, but on the other hand it may be more difficult to metabolize or eliminate them from the body if high amounts are ingested. There are no easy or quick answers that apply to everyone. Many older people are on multiple medications which makes things even more complicated. There is not enough research to fully understand the interactions between natural supplements and medications prescribed for diabetes, high blood pressure, heart disease, cholesterol reduction, and others. However I will provide certain guidelines that you can suit to your specific needs.
Multivitamins - I don't see any major issues with multivitamins as long as the amounts of each ingredient is not too far off the RDA guidelines. The recommended dosage of calcium in postmenopausal women has been lowered in recent years to less than 1,000 or 800 mg a day. Vitamin D is fine at 400 to 2,000 units a day depending on diet and sun exposure.
Herbs - There are herbs that have little or no
noticeable effect on the body, whereas others can speed heart rate and
should be used in caution. Most herbs can be tolerated by older
individuals as well as the young, for instance curcumin, cinnamon,
garlic, basil, echinacea.
Herbs that should be used cautiously by older people include green tea extract, ginseng, ginkgo biloba, rhodiola, St. John's wort, and most aphrodisiac herbs such as tongkat ali, tribulus, maca, etc. since they can speed heart rate and cause sleep problems.
Fruit and berry extracts - I think these are generally quite safe in the young and the elderly. For instance acai, amla, cranberry, goji, pomegranate, mangosteen, maqui, bilberry, noni, etc. Graviola can be used a few nights a week to help with sleep.
Various dietary supplements - I will mention a
few where caution is advised and dosages should be kept low. These are
acetyl l-carnitine, carnosine, alpha lipoic acid, CoQ10, SAM-e,
vinpocetine, CDP-choline, DMAe, TMG and the amino acids tyrosine and
Fish oil, or krill oil, can be used at one to three or four softgels a day.
Probiotics are a common supplement used these days and I don't see a reason why age should be a factor in the dosage.
Glucosamine and chondroitin used for osteoarthritis can be taken in full amounts.
Hormones - Without a doubt the dosages should be
kept very low. This is one area where doctors seem to not recognize how
dangerous high amounts can be. For instance the androgens, DHEA and
testosterone, can cause heart rhythm problems. For several decades
estrogen was prescribed to women in high amounts. It was not until about
a decade ago that certain researchers started warning us of the dangers
of this hormone. Estrogen, in high amounts, is now a suspected
carcinogen since epidemiological evidence associates the hormone to
breast, endometrial, and uterine cancers.
Melatonin is a hormone but it is much much safer than the others mentioned above. A dose of 0.3 mg to 2 mg a few nights a week appears to be safe and potentially beneficial to health.
I am not able to cover all the supplements that are available over the counter but if you have any specific questions regarding a supplement and whether age should influence its intake feel free to email me.
Note about suggested dosage on a bottle label
Keep in mind that the suggested dosages on supplement bottle labels are not necessarily written by experts and sometimes they are way too high. If you have never taken the supplement before, and you are over 60, take a portion of the suggested dosage listed on the label -- at least initially to find out if there is any untoward effect.
Testimonial regarding effective aphrodisiac
I am a 61 year old male in good health, taking no medications, except the occasional use of Viagra which is not working as well as it did years ago. My doctor told me my blood pressure and blood sugar are excellent. Although my wife and I have a good sexual relationship, I find it harder to satisfy her. I used to buy 100 mg Viagra pills and take a quarter of it, and now I need half, or even a full pill, to have a strong erection. However, I wanted to share some good news with you. In the past few months I have tried a number of natural herbal aphrodisiac pills to see if my libido and performance could improve. So far I have tried arginine amino acid, ginseng herb, rhodiola extract, damiana herb, Passion Rx with Yohimbe, tongkat ali 200 mg and LJ100 25 mg (which is a tongkat ali extract). The latter 3 products worked the best. I did not notice much from the amino acids or damiana herb. I now try Passion Rx with Yohimbe, or tongkat ali, two or three days in a row before sexual activity, and, on the day of activity, I take a quarter of the Viagra pill. The herbs seem to prime or pump me up and the additional of the Viagra on the very day (since the medication works within hours) seem to be a great combination. I just wanted to share this with you since it is an example of combining herbal medicine and modern medicine together for optimal benefits that you often talk about. I really feel that my intimacy and sexual relations have improved to back what they were a decade or two ago.
A. Yes, this is my overall philosophy in medicine. Ideally I prefer trying the natural approach. If not effective alone then combining such an approach with modern medications (hopefully at a lower dose to minimize side effects).
Testimonial regarding the negative effects of
cholesterol lowering drugs
I am a 72 year old female with well controlled type 2 diabetes and hypothyroid. However, since beginning a treatment program for high cholesterol and taking Livalo (a statin drug known generically as pitavastatin), my previously slight "essential tremors" of the left hand has dramatically increased. New symptoms include painful muscles in the legs, forearms and wrists. I also have little energy and am experiencing depression for the first time in my life. I have taken metformin for 17 years which has kept my type 2 diabetes well under control, and Synthroid kept my low thyroid under control.A. Cholesterol lowering drugs (the statins such as Lipitor, Zocor, etc.) cause such symptoms much more often than doctors recognize or admit. Muscle aches, low energy, and depression, are not uncommon with their use.
Natural Healing Secrets
Vol. 14, Issue 1 -- January 2017
One of my passions as a medical doctor and nutrition expert is to self-experiment with vitamins, herbs, teas, and all sorts of dietary supplements. I learn from these trials and it helps me understand the published research in a more complete way. I also get feedback from patients and the countless emails we receive from users who tell us about their supplement use and what they notice (I really appreciate reading these anecdotes).
A few weeks ago I experimented with the interesting herb Mucuna Pruriens again (it had been several years since I last tried it). One late afternoon (after I had taken 2 capsules in the morning a half hour before breakfast) I walked in a light drizzle in a park near my home. All the plants, grasses, trees, flowers, and the wetness on them seemed so alive and vibrant. I felt content, in a subtle, peaceful way; life seemed a little more special or magical. This mood elevation was different that what I had experienced on 5-HTP, which influences serotonin levels. It was different than what I had felt on the natural anti-depressants SAM-e and St. John's wort, which influence the levels of several brain chemicals in the brain. Mucuna, also known as velvet bean, is an herb that has a chemical in it called L-Dopa which the body uses to make dopamine. It has been used by Ayurvedic doctors as a natural treatment for Parkinson's disease, depression, and libido improvement. See http://www.raysahelian.com/mucunapruriens.html.
But before I tell you more about it, let me give you a little background how I came about experimenting with dietary supplements and why I believe, as a writer on this topic, it is important that I do so.
My experimental history
Back in the December 1994 I was walking through the vitamin aisle of my local health food store when I noticed a bottle of melatonin on the shelf. From medical school I knew this was a pineal hormone that helped with sleep. I was surprised that it was now available over the counter. The owner of the store told me that they had just received a shipment a week earlier and he did not know what it was good for. I bought a bottle and that very night I took a 3 mg pill. Not only did it help with sleep onset, but in the morning I realized I had had intense, vivid dreams. I knew this hormone supplement was going to be big news and this motivated me to research and write my first book on a supplement (called Melatonin: Nature's Sleeping Pill, which, in 1995, ended up being a bestseller and launched my writing career). I tried the melatonin again several additional nights and each time the vivid dreams occurred again (once in a while I had a nightmare). About that time there were several other books being written on melatonin by researchers who had been studying this hormone for decades. I called one of these researchers, at a university in Texas, and we had a nice chat. I asked him whether he had experienced a similar effect on dreams and his answer astounded me. He said he had never taken melatonin himself, he just gave it to the mice in the laboratory. He was not aware that melatonin caused vivid dreams. I realized at that point that there was so much more to be discovered about all kinds of herbs and supplements that researchers had not even thought about looking into.
For years after that I continued writing books on many topics, including DHEA, creatine, stevia, and then on to Mind Boosters and Natural Sex Boosters. Each time I wrote a chapter on a particular supplement not only did I do a thorough review of the published medical research -- at times it is limited -- but I made sure I tried the supplement myself starting with low doses and increasing daily until I felt something, positive or negative. Over many decades of doing this self-experimentation I have learned an enormous amount about their effects on my body and I am now very sensitive to any changes that occur.
Back to the mucuna pruriens supplement
Mucuna is of one of the few plants in nature that contains L-dopa in a significant concentration. Most species have a content of about 2 to 5% L-dopa per weight. Mucuna, as a supplement, is sold as a regular powder and also in a more concentrated form where the content of L-dopa in the herb is increased. The product I tried is by Physician Formulas which has a L-dopa content standardized to 15%. Each pill has a total of 200 mg of the herb hence the content of L-dopa is 30 mg per pill. See http://physicianformulas.com/products/mucuna-pruiens-extract-200-mg-60-capsules-l-dopa-natural-dopamine-increase.
Mind you most herbs have dozens of substances in them and it is not easy to determine exactly which substance is having what kind of effect on the body or mind since they are all being ingested at the same time and working in our cells and tissues in multiple ways. The benefits that I noticed from mucuna were likely due to the L-dopa content (I took two pills which had a total of 60 mg L-dopa), combined with the other beneficial substances within the plant. Over the next few weeks I plan to continue experimenting with it in different amounts. If you wish to email me your feedback I would be very interested.
Other products online
There are some mucuna products sold online that have a concentration of L-dopa higher than 15% but they may come at the expense of some of the other beneficial substances within the plant. These are okay to use occasionally but I am concerned about the potential toxicity of high concentrations or amounts of L-dopa used for prolonged periods. When patients with Parkinson's disease are given dopaminergic medications, such as L-dopa, for several years, a condition known as drug-induced dyskinesia can occur.
L-dopa is considered the 'gold standard' for the treatment of Parkinson's disease but high amounts of L-dopa are harmful to brain cells. Fortunately the various beneficial substances within the mucuna plant have shown to be protective against the possible harmful effects of high concentrations of L-dopa. In this instance nature has provided an active ingredient in this plant, the L-dopa, along with various other substances that protect the body and brain. Modern nutritional science is able to concentrate the active ingredient while still keeping most of the rest of the beneficial substances in the pill.
After decades of experimentation I still find this whole field quite fascinating. There is so much to be learned about plants and so many possibilities for medical treatment when used alone, in combination with other dietary supplements, or with medications.
After this experimentation I revised my page on depression to include mucuna as another option to improve mood. We now have at least four dietary supplements that have a strong and immediate influence including 5-htp, Mucuna, SAM-e, and St. John's wort. See http://www.raysahelian.com/depression.html.
Tip: If you plan to take a supplement for the first time, just take it alone without other pills so you know exactly what it is doing without interference. Please review with your health care provider before you experiment with these pills especially if you have a health condition, are older, or are taking medications.