Indian Trumpetflower Seed Extract --  Mu Hu Die -- Common name -- Midnight Horror

For a list of herbs used in Chinese medicine, see Chinese Herbs.

Oroxylum Indicum Benefits
Lab studies show the seeds of oroxylum indicum to have anti-tumor potential.

Oroxylum Indicum Chemical Composition
The seeds of oroxylum have a high content of flavonoids, including baicalein and chrysin.

Historical Uses
Oroxylum indicum has been used for cough and wheeze

Oroxylum indicum Research Update
Studies of the anti cancer potential of plants used in Bangladeshi folk medicine.
J Ethnopharmacol. 2005 May 13;99(1):21-30.
The present study evaluated the anticancer potential of 11 plants used in Bangladeshi folk medicine. The extracts were tested for cytotoxicity using the brine shrimp lethality assay, sea urchin eggs assay, hemolysis assay and MTT assay using tumor cell lines. The extract of Oroxylum indicum showed the highest toxicity on all tumor cell lines tested. The extract of Aegle marmelos exhibited toxicity on all used assays, but in a lower potency than Oroxylum indicum. In conclusion, among all tested extracts, only the extracts of Oroxylum indicum, Moringa oleifera and Aegles marmelos could be considered as potential sources of anticancer compounds. Further studies are necessary for chemical characterization of the active principles and more extensive biological evaluations.

Comparison of high-speed counter-current chromatography instruments for the separation of the extracts of the seeds of Oroxylum indicum.
J Chromatogr A. 2005 Jan 21;1063(1-2):241-5.
Analytical Milli high-speed counter-current chromatography (HSCCC) was used for the selection and optimization of the two-phase solvent system to separate flavonoids from the extracts of the seeds of Oroxylum indicum. Four flavonoids were isolated by preparative HSCCC: baicalein-7-O-diglucoside (25.0 mg, 92% purity), baicalein-7-o-glucoside (50.4 mg; 95% purity), baicalein (75 mg; purity 98%) and chrysin (100 mg; purity 98%).

Isolation and identification of four flavonoid constituents from the seeds of Oroxylum indicum by high-speed counter-current chromatography.
J Chromatogr A. 2003 Feb 21;988(1):95-105.
Four flavonoids, chrysin, baicalein, baicalein-7-O-glucoside, baicalein-7-O-diglucoside (Oroxylin B) and one unknown flavonoid have been isolated and purified for the first time in the seeds of Oroxylum indicum.

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