Panax Ginseng root extract by Ray Sahelian, M.D. Health benefit of panax ginseng extract

The root of the panax ginseng plant has been used in China, Japan, and Korea for many centuries for enhancing vitality. There are several varieties of ginseng sold over the counter: Asian ginseng ( Panax ginseng ), American Ginseng ( Panax quinquefolius ), and Siberian ginseng ( Eleutherococcus Chinensis ) are the most common. Hundreds of ginseng products are available over the counter with different dosages and combinations.

Panax Ginseng root, 400 mg
Panax Ginseng root supplement Facts:
 Panax Ginseng Root - 400 mg * (contains 8 percent ginsenosides = 32 mg)

Suggested Use: One panax ginseng root capsule in the morning a few times a week or as recommended by your health care professional.

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Panax ginseng and blood sugar
Single doses of the traditional herbal treatment Panax ginseng have been shown to lower blood glucose levels and elicit cognitive improvements in healthy volunteers. The specific mechanisms responsible for these effects are not known. However, cognitive improvements may be related to the glycemic properties of panax ginseng. Those with diabetes who plan to take panax ginseng herb for prolonged periods should use low dosages since one side effect of high dose panax ginseng is insomnia.

The glycemic effects of single doses of Panax ginseng in young healthy volunteers.
Br J Nutr. 2006 October. Human Cognitive Neuroscience Unit, Division of Psychology, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.
The results of two acute placebo-controlled, double-blind cross-over studies assessing the effect of Panax ginseng (G115) on blood glucose levels are reported. In study 1, thirty participants received three treatments: placebo; 200 mg G115; 400 mg G115. In study 2, twenty-seven participants received four treatments: placebo (0 mg ginseng and 30 mg saccharin); ginseng (200 mg ginseng and 30 mg saccharin); placebo-glucose (0 mg ginseng and 25 g oral glucose); ginseng-glucose (200 mg ginseng and 25 g oral glucose). Blood glucose levels were measured at baseline (at 09.00 hours after an overnight fast) and then 60, 90 (study 1 only) and 120 min post-dose. Both studies demonstrated that G115 alone significantly lowers fasting blood glucose levels. Conversely, in study 2 there was a significant drink x ginseng interaction suggesting opposing glycemic effects of ginseng under fasting and raised blood glucose conditions.

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Panax ginseng and acrylamide
Panax ginseng extract has efficacies such as anticancer, antihypertension, antidiabetes and antinociception. The objective of the current study is to evaluate the protective effects of Panax ginseng extract against acrylamide -induced toxicity in rats. Treatment with Panax ginseng before, during or after acrylamide treatment reduced or partially antagonized the effects induced by acrylamide towards the normal values of controls. It could be concluded that Panax ginseng extract exhibited a protective action against acrylamide toxicity and it is worth noting that treatment with Panax ginseng extract before or at the same time as acrylamide treatment was more effective than when administered after acrylamide treatment.

Panax ginseng as an ACE ihibitor?
Panax ginseng (G115) inhibits ACE activity, but does not affect nitric oxide production in cultured human endothelial cells from umbilical veins (HUVEC) and bovine mesenteric arteries (BMA).

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This panax ginseng page was last updated in February 2008.