Pau D'arco bark supplement by Ray Sahelian, M.D. Pau D'arco shrub health benefit

Pau D'arco ( Tabebuia impetiginosa, syn. Tabebuia avellanedae ) is a tree from South America whose inner bark has been used as an analgesic (pain reliever), anti-inflammatory, anti-cancer, anti-bacterial, and diuretic. Little research is available in the North American medical literature regarding the medicinal properties of pau d’arco. At present it is difficult to make any clinical recommendations with certainty regarding the medicinal properties and uses of this interesting plant.
   Pau D'arco has antioxidant properties at a power similar to vitamin E (see below).

Pau D'Arco supplement, 500 mg

Pau D' Arco (Tabebuia altissima) is the highest quality inner bark of the Purple Lapacho tree found in Brazil and Northern Argentina. Ever since ancient times, when it was a standard for the medicine men of the Inca Empire, pau d'arco (also known as ipe roxo and taheebo) has been one of the most widely used herbs in South America. Its popularity is attributed to the active constituents, lapachol and beta-lapachone, which have been the subject of numerous scientific studies.

Pau Darco Supplement Facts:
Pau D'Arco Bark  (Tabebuia altissima)

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Pau D'arco availability
You can find Pau D'arco in tablet or capsule form, as Pau D'arco tea, and combined with other nutrients and herbs in many formulas.

Beta-lapachone is found in Pau D'arco
Beta-Lapachone is a novel anticancer agent found in Pau D'arco with selectivity against prostate cancer and possibly retinoblastoma and other cancers. Beta lapachone is being studied either by itself or in combination with chemotherapy drugs as a treatment for various types of cancer.

Pau D'arco Research studies
Constituents from the bark of Tabebuia impetiginosa Pau D'arco.
Phytochemistry. 2004 Jul;65(13):2003-11.
The bark of pau darco afforded nineteen glycosides, consisting of four iridoid glycosides, two lignan glycosides, two isocoumarin glycosides, three phenylethanoid glycosides and eight phenolic glycosides. Iridoid glycosides, phenylethanoid glycosides and lignan glycosides had ajugol, osmanthuside H and secoisolariciresinol 4-O-beta-D-glucopyranoside as their structural elements, respectively, whereas the aglycone moieties of the isocoumarin glycosides were considered to be (-)-6-hydroxymellein. Phenolic glycosides had 4-methoxyphenol, 2,4-dimethoxyphenol, 3,4-dimethoxyphenol, 3,4,5-trimethoxyphenol and vanillyl 4-hydroxybenzoate as each aglycone moiety. Additionally, the sugar chains of these isocoumarin glycosides and phenolic glycosides were concluded to be beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside as well as those of osmanthuside H and above phenylethanoid glycosides.

Antioxidant activity and characterization of volatile constituents of Taheebo (Tabebuia impetiginosa Martius ex DC) - Pau D'arco.
J Agric Food Chem 2003 Jan 1;51(1):295-300. Park BS,. U.S. Department of Agriculture, Albany, California.
Volatiles were isolated from the dried inner bark of Tabebuia impetiginosa ( pau d'arco ). The major volatile constituents of pau darco were 4-methoxybenzaldehyde, 4-methoxyphenol, 5-allyl-1,2,3-trimethoxybenzene (elemicin), 1-methoxy-4-(1E)-1-propenylbenzene (trans-anethole), and 4-methoxybenzyl alcohol. The antioxidant activity of the volatiles was evaluated using two different assays. The extract exhibited a potent inhibitory effect on the formation of conjugated diene hydroperoxides (from methyl linoleate). The extract also inhibited the oxidation of hexanal for 40 days at a level of 5 microg/mL. The antioxidative activity of pau darco volatiles was comparable with that of the well-known antioxidants, alpha-tocopherol, and butylated hydroxytoluene.

Different species of Tabebula
Tabebuia altissima
Tabebuia avellanedae
Tabebuia impetiginosa

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