Petadolex contains the patented extract of butterbur that supports healthy blood vessel tone in the brain, as well as normal blood flow in the brain.* Butterbur has been the subject of several placebo-controlled clinical studies.
Petadolex butterbur supplement by Ray Sahelian, M.D.
Petadolex is made by Weber and Weber GmbH and Co. Petadolex is a patented, standardized CO2 rhizome root extraction of Petasites marketed in Europe since 1992.
Petadolex ( Butturbur
extract ) 60 Softgels -
Enzymatic Therapy
Petadolex contains the patented extract of butterbur that supports healthy
blood vessel tone in the brain, as well as normal blood flow in the
brain.* Butterbur has been the subject of several placebo-controlled
clinical studies.
Petadolex is standardized to contain 15% of butterbur's key ingredient, petasin. It's also guaranteed to be pyrrolizidine alkaloid (PA) free, so you can use it with confidence. PA's are toxic compounds that can harm the liver. Studies demonstrate patented Petadolex is safe and well tolerated.
Petadolex for asthma
Petasites hybridus (Butterbur root) extract in the treatment of asthma--an
open trial.
Altern Med Rev. 2004 March. Danesch UC. University of Heidelberg,
Germany.
The efficacy and tolerability of a butterbur root extract Petadolex for
the treatment of asthma was analyzed in a prospective, non-randomized,
open trial. Subjects included 64 adults and 16 children/adolescents
treated for two months with the extract, followed by two months during
which the intake of the extract was optional. Concomitant asthma
medication was permitted. The number, duration, and severity of asthma
attacks decreased, while peak flow, forced expiratory volume, and all
measured symptoms improved during Petadolex therapy. In addition, more
than 40 percent of patients using asthma medications at baseline reduced
intake of these medications by the end of the study. This study suggests
the Petasites hybridus extract Petadolex is an effective and safe therapy
for the treatment of asthma.
Petadolex for migraine
Butterbur root extract Petadolex and music therapy in the prevention of
childhood migraine: an explorative study.
Eur J Pain. 2008 April. Department of Child and Adolescent Psychiatry,
University of Heidelberg, Blumenstrasse 8, D-69115 Heidelberg, Germany.
This study was to assess efficacy of a butterbur root extract Petadolex
and music therapy in primary school children with migraine. Following a
8-week baseline patients were randomized and received either Petadolex,
music therapy, or placebo over 12 weeks. During post-treatment, only music
therapy was superior to placebo, whereas in the follow-up period both
music therapy and Petadolex were superior to placebo. All groups showed a
substantial reduction of attack frequency already during baseline.
Petadolex and music therapy might be superior to placebo and may represent
promising treatment approaches in the prophylaxis of pediatric migraine.
Effectiveness of Petasites hybridus preparations in
the prophylaxis of migraine: a systematic review.
Phytomedicine. 2006 November. Headache Center Hirslanden,
Münchhaldenstr. 33, 8008 Zürich, Switzerland.
The objective of this review was to evaluate the strength of evidence of
effectiveness for Petasites hybridus in the prophylaxis of migraine.
Several databases and other sources were searched to identify randomised-controlled
trials investigating Petasites hybridus preparations. Two trials totalling
293 patients (60 and 233 patients) were included in this review. Both
trials investigated the proprietary Petasites root extract Petadolex. The
Petadolex extract at higher dose (150 mg) showed a greater decreased
frequency of migraine attacks and a greater number of responders
(improvement>50%) after treatment over 3-4 months than the extract at
lower dose (100 mg) and placebo. Moderate evidence of effectiveness is,
thus, available for a higher than the recommended dose of the proprietary
Petasites root extract Petadolex in the prophylaxis of migraine.