Phytic acid, Phytates by
Ray Sahelian, M.D.
January 20 2017
Phytic acid ( Inositol hexaphosphate, IP-6, or phytate ), is a naturally polyphosphorylated carbohydrate found in cereal grains, beans, brown rice, corn, sesame seeds, wheat bran, and other high fiber foods. Phytic acid helps in the metabolism of insulin and calcium, hair growth, bone marrow cell metabolism, eye membrane development, and helps the liver transfer fat to other parts of the body. Phytic acid in the diet may even help reduce the risk for kidney stones. Many researchers believe that some of its health benefits may be due to the antioxidant, immune enhancing, and cardiovascular supporting activities. In-vitro and animal research has shown phytic acid to have significant protective and growth regulating effects on various cells and tissues including those of the colon, breast, and prostate.
Aortic calicification prevention
J Ren Nutr. 2016. Protective Effect of Myo-Inositol Hexaphosphate Phytate on Abdominal Aortic Calcification in Patients With Chronic Kidney Disease. The aim of this study was to evaluate the relationship between physiological levels of myo-inositol hexaphosphate -- phytate -- and cardiovascular (CV) calcification in patients with chronic kidney disease (CKD). Our results suggest that adequate consumption of phytate can prevent AAC in patients with chronic kidney disease. Further prospective studies must be performed to elucidate the benefits of a phytate-rich diet and the associated risk of phosphorus bioavailability in these patients.
Eur J Pharmacol. 2015. Phytic acid suppresses ischemia-induced hydroxyl radical generation in rat myocardium. Results suggest that phytic acid is associated with antioxidant effect due to the suppression of iron-induced ĽOH generation.
Fitoterapia. 2014 Jan 21. Phytic acid enhances the oral absorption of isorhamnetin, quercetin, and kaempferol in total flavones of Hippophae rhamnoides L. The oral bioavailability of isorhamnetin, kaempferol, and quercetin in TFH was enhanced by the co-administration of IP6. The main mechanisms are related to their enhanced aqueous solubility and permeability in the presence of IP6. In summary, IP6 is a potential absorption enhancer for pharmaceutical formulations that is both effective and safe.
I have been seeing recommendations that grains
be soaked to rid them of phytates that are said to interfere with mineral
I do not feel this is necessary, certain amounts of phytates in the diet are healthy.