Pimecrolimus medication by Ray Sahelian, M.D.

Pimecrolimus is an pharmaceutical medication used in the treatment of atopic dermatitis (eczema). Pimecrolimus is currently available as a topical cream. Pimecrolimus is sold by Novartis, under the trade name Elidel.

Pimecrolimus Caution

Two topical eczema drugs, Elidel Cream ( pimecrolimus ) and Protopic Ointment ( tacrolimus ) must have a boxed warning about a possible risk of cancer. These drugs are recommended for use as second-line treatments. This means that other prescription topical medicines should be tried first. Use of these drugs in children under 2 years of age is not recommended.

Pimecrolimus for Steroid Induced Erythema in Rosacea

Steroid-induced erythema in rosacea is a therapeutic challenge because of its tendency to rebound. The condition may improve when steroid treatment is discontinued and therapy with pimecrolimus cream 1% twice daily initiated. The calcineurin antagonist pimecrolimus may offer an option in the acute therapy of steroid-aggravated facial dermatoses.

Pimecroliums cream for asteatotic eczema
Pimecrolimus cream 1% is effective in asteatotic eczema: results of a randomized, double-blind, vehicle-controlled study in 40 patients. J Eur Acad Dermatol Venereol. 2007 Jan;21(1):90-4. Department of Dermatology, University Clinics Munster, Munster, Germany.
Pimecrolimus cream 1% is a treatment for atopic eczema. The aim was to investigate the efficacy of pimecrolimus cream in asteatotic eczema, a skin disease similar to atopic eczema and its associated dry skin and itching. Results After 4 weeks of treatment showed pimecrolimus was helpful. With pimecrolimus there was better control of pruritus. Conclusion Pimecrolimus cream 1% is effective in patients with asteatotic eczema.