Probiotic by Ray Sahelian, M.D.

A probiotic supplement can have many health benefits. Once you buy a probiotic supplement, you should refrigerated it to prolong the shelf life.

Enhanced Probiotic System, Jarrow Formulas


• Higher Potency 4.4 Billion Organisms per capsules
• Species with Documented strain morinaga Bifidobacteria longum BB536
• Dairy Free
• Vegetarian
• Enteric Coated!
• Room Temperature Stable! No Refrigeration Required!
• For Intestinal and Immune Health
• Probiotic Supplement
• Individually Blister Sealed
 


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Supplement Research Update newsletter. Twice a month you will receive a brief abstract of 4 to 6 studies on various supplements and natural medicine topics - including probiotic supplement benefit - and their practical interpretation by Ray Sahelian, M.D.

Jarro-Dophilus enhanced probiotic system is room temperature stable, but preferably refrigerate to safeguard product from heat. Blister packaging each capsule provides extra protection to the bacteria against moister and oxygen.
At time of manufacture, each capsule contains approximately 4.4 Billion organisms. Jarro-Dophilus enhanced probiotic system is room temperature stable and enteric-coated, delivering directly into the intestines 8 different species of probiotics representing 4 genera of bacteria: Lactobacilllus, Bifidobacteria, Lactococcus and Pediococcus Bifodobacteria longum BB536 (moringa strain) has been shown to colonize, stimulate immune response and suppress intestinal pathogens. L. rhamnosus R0011 is a unique, high producer of polysaccharides, which facilitate colonization and stimulate intestinal immune response. Lactococcus and Pediococcus help reduce spoilage caused by undesirable bacteria in cultured dairy products.

Probiotic Supplement Facts:
Probiotic Bacteria 4.4 Billion *
Organisms
L. rhamnosus R0011 (15.4%) 680 Million
L. casei R0256 (15.4%) 680 Million
L. plantarum R0202 (7.7%) 340 Million
L. acidophilus R0052 (15.4%) 680 Million
B. longum BB536 (morinaga strain)(15.4%) 680 Million
B. breve R0070 (7.7%) 340 Million
Pediococcus (15.3%) 670 Million

acidilactici R1001
lactococcus (7.6%) 330 Million
diacetylactis R0100

Benefit of Probiotics
Probiotic have been defined as live microorganisms that (when ingested) have a beneficial effect in the prevention and treatment of specific medical conditions. These microorganisms are believed to exert biological effects through a phenomenon known as colonization resistance, whereby the indigenous anaerobic flora limits the concentration of potentially harmful (mostly aerobic) germs in the digestive tract. Other modes of action, such as supplying enzymes or influencing enzyme activity in the gastrointestinal tract, may also account for some of the other functions that have been attributed to probiotic.

Prebiotic are nondigestible food ingredients that beneficially affect host health by selectively stimulating the growth and/or activity of bacteria in the colon. The prebiotic, fructooligosaccharide (FOS), is found naturally in many foods, such as wheat, onions, bananas, honey, garlic, or leeks. They can also be isolated from chicory root or synthesized enzymatically from sucrose. Fermentation of FOS in the colon results in a large number of physiologic effects including increasing the numbers of bifidobacteria in the colon, increasing calcium absorption, increasing fecal weight, shortening of gastrointestinal transit time, and possibly lowering blood lipid levels. The increase in bifidobacteria has been assumed to benefit human health by producing compounds to inhibit potential pathogens, by reducing blood ammonia levels, and by producing vitamins and digestive enzymes.

A probiotic supplement enhances systemic cellular immune responses and may be useful as a dietary supplement to boost natural immunity in otherwise healthy adults.

Children who take probiotic containing milk may suffer fewer respiratory infections.

Probiotic formulation for diarrhea
Dr. Alfredo Guarino, from the University of Naples in Italy, enrolled 571 children, between 3 and 36 months of age, who presented to a pediatrician with acute diarrhea. The children were randomized to an oral rehydration control group or to one of five probiotic groups (all formulations were given twice daily plus oral rehydration): Lactobacillus rhamnosus strain GG; Saccharomyces boulardii; Bacillus clausii; Enterococcus faecium SF68; or a mixture of L. delbrueckii var bulgaricus, Streptococcus thermophilus, L. acidophilus, and Bifidobacterium bifidum. Compared with oral rehydration alone, treatment with the L. rhamnosus strain GG or the mixture of four probiotic strains significantly reduced the median duration of diarrhea from 115.0 hours to 78.5 and 70.0 hours, respectively. By contrast, the other probiotic treatments had no significant effect on the duration or frequency of diarrhea.

Probiotic and Irritable Bowel Syndrome
Probiotic supplements may be helpful in Irritable Bowel Syndrome.


Probiotic supplements and immune system.
Effects of probiotic therapy in critically ill patients: a randomized, double-blind, placebo-controlled trial
American Journal of Clinical Nutrition, Vol. 85, No. 3, 816-823, March 2007. From the Royal Alexandra Hospital, Edmonton, Canada; the Department of Medicine, Division of Gastroenterology, and the Department of Agricultural, Food, and Nutritional Science, University of Alberta, Edmonton, Canada
Multiple organ dysfunction syndrome (MODS) is a major cause of mortality in intensive care units. A breakdown in gut barrier function and immune dysfunction are associated with the onset of MODS. Probiotic bacteria have been shown to modulate intestinal barrier and immune function. This study assessed the efficacy of a probiotic compound in a viable and nonviable formulation in modulating intestinal permeability and immune function and preventing the onset of MODS in patients in the intensive care unit. A double-blind, randomized controlled trial was conducted in the intensive care unit of a tertiary care teaching hospital. Twenty-eight critically ill patients admitted to the intensive care unit were randomly assigned to receive 1 of 3 treatments daily for 7 d: 1) placebo, 2) viable probiotics, or 3) equivalent probiotic sonicates. MODS scores and systemic concentrations of immunoglobulin (Ig) A and IgG were measured on days –1, 4, and 7, and intestinal permeability measurements were taken daily. The patients responded to viable probiotics with a significantly larger increase in systemic IgA and IgG concentrations than in the patients who received placebo or sonicates. MODS scores were not significantly affected by probiotic treatment. Over the study period, intestinal permeability decreased in most patients. Patients receiving viable probiotics show a greater enhancement in immune activity than do patients receiving either placebo or probiotic bacterial sonicates.

Probiotic supplement for athletes
Endurance runners or other athletes have strenuous training regimens which can erode their immunity and make them more vulnerable to catching colds or other viruses. A daily dose of probiotic bacteria enahnces their immune system and help reduce the risk for infections.

See also prebiotic

Probiotic Research Update
Compared with standard formulas, those containing beneficial "probiotic" organisms seem to reduce the number and duration of diarrhea episodes in infants attending childcare centers. Of two types of probiotic tested -- Lactobacillus reuteri and Bifidobacterium lactis -- L. reuteri may be the better supplement, according to the report in the medical journal Pediatrics. Dr. Zvi Weizman, from Soroka Medical Center in Beer-Sheva, Israel, and colleagues assessed various infectious outcomes in 201 infants randomly given formula supplemented with L. reuteri, B. lactis, or no probiotic. All of the infants were healthy and attended childcare centers in Beer-Sheva. In addition to having fewer and shorter diarrhea episodes, infants treated with the probiotic formulas also had fewer episodes of fever. Compared with the other groups, the L. reuteri group also had significantly fewer clinic visits, childcare absences, antibiotic prescriptions, and days with fever. "The present controlled study is the first to compare two different species of probiotic microorganisms and their efficacy in the prevention of common infectious illnesses in childcare infants," Weizman's team states. "In most of the parameters studied, the differences were consistently in favor of L. reuteri," the researchers add. SOURCE: Pediatrics, January 2005.

Australian researchers have modified probiotic microbes -- "good" bacteria -- that may be useful in preventing or treating travelers' diarrhea, an all too common problem during trips to certain countries. The probiotic microbes work against a type of E. coli bacteria that causes diarrhea by producing a chemical that is toxic to intestinal cells. The probiotic microbes carry a molecule that looks a lot like the toxin receptor found on intestinal cells. This mimicry causes the toxin to bind to the microbes instead of the intestinal cells. Lab tests showed that these probiotic organisms could bind and neutralize a significant amount of enterotoxin, according to a report in the medical journal Gastroenterology. Moreover, treatment with these agents conferred significant intestinal protection in rabbits exposed to the toxin. The results suggest that these probiotic microbes could be a useful treatment for traveler's diarrhea caused by E. coli, the researchers state.

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Probiotic Use to Expand
BASF is targeting the oral care and cosmetics markets with an ingredient more commonly used as a probiotic in food. The German ingredients giant has been developing solutions with another German firm, Biotech Organo Balance, since 2002 and is close to fruition with a probiotic Lactobaccilus ingredient it foresees having skin care, oral hygiene and deodorant applications. Company researcher Dr Andreas Reindl, project leader at BASF Future Business says, "With lactobacillus anti-caries we have found an antagonist which effectively binds to the caries germs and prevents them adhering to the surface of the teeth."Skin and deodorant applications are also being developed.

Probiotic emails
Q. Is there any such thing as a probiotic suppository available for women to use to fight yeast infections. If so where can I get them and what are the ingredients?
   A. There are some products that are sold as being probiotic suppositories for women. However, we don't have any knowledge on how well they work. If you do a google search for " probiotic suppository " you will find them.