July 1 2017 by Ray Sahelian, M.D.
Pueraria tuberosa is a woody legume. Pueraria tuberosa is the botanical name for the herb known as Indian Kudzu.
Nat Prod Res. 2014. Pueraria tuberosa: a review on its phytochemical and therapeutic potential. Pueraria tuberosa is a perennial herb commonly known as 'vidarikanda', distributed throughout south east Asia. The plant's tuber is widely used in ethanomedicine as well as in traditional systems of medicine, particularly in ayurveda. It has been used in various ayurvedic formulations as restorative tonic, antiaging, spermatogenic and immune booster and has been recommended for the treatment of cardiovascular diseases, hepatosplenomegaly, fertility disorders, menopausal syndrome, sexual debility and spermatorrhoea. Numerous bioactive phytochemicals, mostly isoflavonoids such as puerarin, genistein, daidzein, tuberosin and so on have been identified in the tuber. In vivo and in vitro studies have provided the support against traditional demands of the tuber as spermatogenic, immune booster, aphrodisiac, anti-inflammatory, cardiotonic and brain tonic.
AYU (An International Quarterly Journal of Research in Ayurveda) 2013. Anti-inflammatory effect of Pueraria tuberosa extracts through improvement in activity of red blood cell anti-oxidant enzymes.
Isoflavonoids production in callus culture of Pueraria tuberosa, the
Indian J Exp Biol. 2006. Vaishnav K, Goyal S, Ramawat KG. Laboratory of Biomolecular Technology, Department of Botany, M L Sukhadia University, Udaipur 313 001, India.
Isoflavonoid contents of different plant parts and callus tissues of Pueraria tuberosa are presented. The initial cultures were slow growing, associated with browning of the tissues. The production of four isoflavonoids (puerarin, genistin, genistein and daidzein) in the callus cultures of Pueraria tuberosa was studied by manipulating the plant growth regulators and sucrose concentration in the medium. Organogenesis was not recorded in callus on any of these treatments. Tuber and stem accumulated puerarin, a glycoside of daidzein, at high amounts, 0.65% and 0.054% respectively. However, the daidzein content of the callus tissues grown on Murashige and Skoog medium containing BA (20 microM) and sucrose (60 gl(-1)) was significantly higher (0.056%) than in vivo plant material (0.02%) and other comparable culture systems like Genista and Pueraria lobata.