Sage Herb by Ray Sahelian, M.D. Health benefit of sage herb
There are
many species of the sage herb, each with its own characteristics that make
them have different uses.
Common types of sage herb are garden (Salvia officinalis
L.), Spanish sage herb (Salvia lavandulaefolia) and glutinous sage herb (Salvia glutinosa L.). The leaves of sage
herb (Salvia officinalis
L., Lamiaceae) are reported to have a wide range of biological activities,
such as anti-bacterial, fungistatic, virustatic, astringent, eupeptic and
anti-hydrotic effects. Spanish sage herb has been studied for its mood and
memory improving potential. Sage herb has blood sugar lowering activity and
antioxidants which have liver protective properties. Sage is found in
Good Night Rx.
Good Night Rx with sage root
Developed by Ray Sahelian, M.D.

Good Night Rx
with sage root and more than a dozen herbs and nutrients for sedation helps you
fall asleep and stay asleep without the side effects common to prescription
sleeping pills.
Suggested Use:
Take one capsule of Good Night Rx one to three hours before sleep, preferably
on an empty stomach. Good Night Rx does not work as well
when taken with a meal.
For a list of the ingredients and more information regarding Good Night Rx
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Historical Thoughts about Sage herb
Sage (Salvia) has a longstanding reputation in British herbal encyclopaedias as an agent that enhances memory.
Sage and
Memory
Scientists at the Universities of Newcastle and Northumbria tested 44 people,
who were either given sage herb or a dummy placebo pill. They found that those
given the sage oil tablets performed much better in a "word recall test". The
Medicinal Plant Research Centre (MPRC) at the universities are testing many
old-fashioned claims about the healing powers of herbs and flowers. Sage is
often referred to in ancient texts - in 1597 the herbalist John Gerard said that
it was "singularly good for the head and quickeneth the nerves and memory."
Salvia officinalis (sage) has been shown to possess in
vitro cholinesterase inhibiting properties, and to enhance mnemonic performance
and improve mood.
Acetylcholinesterase Inhibition and Alzheimer's
Butyryl- and acetyl-cholinesterase inhibitory activities in essential oils of Salvia species and their constituents have been found.
Constituents of Sage Plant
There are a number of chemicals within the sage plant including terpenoid constituents 1,8-cineole, camphor, alpha-pinene, beta-pinene, borneol, caryophyllene oxide, linalool and bornyl acetate. The amount of rosmarinic acid in borage leaves is similar compared with Sage plant - Salvia officinalis (15 mg/g).
Availability of Sage plant
The sage leaves and stems are used in cooking for flavoring sausages, pork, sauces, cheese, dressings and stuffing. Sage tea is also brewed. Italian cooks have used sage for centuries to add a flavorful and healthful kick to vegetable and meat dishes. Americans all know sage from the traditional Thanksgiving turkey dinners
Sage
Plant Research
Positive modulation of mood and cognitive performance following administration
of acute doses of Salvia lavandulaefolia essential oil - sage plant - to healthy young
volunteers.
Physiol Behav. 2005 Jan 17;83(5):699-709. Tildesley NT, Kennedy DO, Perry EK,
Ballard CG, Wesnes KA, Scholey AB.
Human Cognitive Neuroscience Unit, Division of Psychology, Northumbria
University, Newcastle upon Tyne, NE1 8ST, UK.
Members of the Sage family, such as Salvia officinalis and Salvia
lavandulaefolia, have a long history of use as memory-enhancing agents coupled
with cholinergic properties that may potentially be relevant to the amelioration
of the cognitive deficits associated with Alzheimer's disease. The current study
utilised a placebo-controlled, double-blind, balanced, crossover design in order
to comprehensively assess any mood and cognition modulation by S.
lavandulaefolia. Twenty-four participants received single doses of placebo, 25
microl and 50 microl of a standardised essential oil of S. lavandulaefolia in an
order dictated by a Latin square. Doses were separated by a 7-day washout
period. Results: These results represent further evidence that Salvia is capable
of acute modulation of mood and cognition in healthy young adults. The data also
suggest that previous reports of memory enhancement by Salvia may be due to more
efficient retrieval of target material.
Salvia
lavandulaefolia (Spanish sage) enhances memory in healthy young volunteers.
Pharmacol Biochem Behav. 2003 Jun;75(3):669-74. Tildesley NT, Kennedy DO,
Perry EK, Ballard CG, Savelev S, Wesnes KA, Scholey AB. Human Cognitive
Neuroscience Unit, Division of Psychology, Northumbria University, Newcastle
upon Tyne NE1 8ST, UK.
Based on known pharmacokinetic and binding properties, it was hypothesised that
acute administration of sage would enhance memory in young adult volunteers. Two
experiments utilised a placebo-controlled, double-blind, balanced, crossover
methodology. In Trial 1, 20 participants received 50, 100 and 150 microl of a
standardised essential oil extract of Salvia lavandulaefolia and placebo. In
Trial 2, 24 participants received 25 and 50 microl of a standardised essential
oil extract of S. lavandulaefolia and placebo. Doses were separated by a 7-day
washout period with treatment order determined by Latin squares. Assessment was
undertaken using the Cognitive Drug Research computerised test battery prior to
treatment and 1, 2.5, 4 and 6 h thereafter. The 50 microl dose of Salvia
essential oil significantly improved immediate word recall in both studies.
These results represent the first systematic evidence that Salvia is capable of
acute modulation of cognition in healthy young adults.
Sage email
Q. Can a sage supplement be taken the same day as
resveratrol?
A. I don't see why not.