Shen Min by Ray Sahelian, M.D.
Shen-Min is a Chinese herb formula with a mixture of several plants and vitamins including Polygonum multiflorum, a root that has been previously associated with hepatotoxicity.
Acute hepatitis due to shen-min: a herbal product derived from Polygonum
multiflorum.
J Clin Gastroenterol. 2006 August. Division of Gastroenterology and Hepatology,
Hospital Pablo Tobón Uribe and Gastro-Hepatology Group, University of Antioquia,
Medellín, Colombia.
Shen-Min is a herbal product sold as a supplement for women to enhance hair
growth. It is widely available across Asia, Europe, and the United States and
sold without prescription as a hair nutritional supplement. We describe a case
of acute liver injury in a 28-year-old white woman who developed symptomatic
hepatitis 8 weeks after starting Shen-Min. All other potential causes of acute
hepatitis including viral, hypoxic/ischemic, metabolic, and autoimmune
etiologies were excluded. The liver injury slowly resolved over 3 weeks after
discontinuing the herbal product. Although the mechanism of Shen-Min
hepatotoxicity is unknown, we suspect an idiosyncratic reaction because the
patient developed a fine maculopapular rash, mild eosinophilia, and did not
overdose. To our knowledge this is the first reported case of herbal-induced
hepatotoxicity in a patient taking Shen-Min per se. Clinicians taking care of
patients with acute hepatitis of unclear etiology should be aware that the
consumption of Shen-Min, a hair supplement widely available in the United States
and Western countries might cause acute hepatitis.
Comments: It is not fully clear whether He Shoo Wu or the other
plants, or the combination, in this product were involved in damaging the liver.