With the incidence of skin cancer doubling in the last 20 years, it is becoming more and more important for health professionals to be able to identify these dangerous malignancies. Skin cancer is more likely to occur in individuals of light complexion who have had significant exposure to sunlight, and both types of skin cancer are more common in the southern latitudes of the Northern hemisphere.
Cause of Skin Cancer
Sun exposure
Indoor tanning - tanning beds are a cause of skin cancer
Genetic predisposition
Unhealthy diet for several decades - Diet and skin cancer - A diet comprised of
high meat and fat intakes increases squamous cell carcinoma tumor risk,
particularly in persons with a skin cancer history.
Pale skin color
Job exposure to radiation ups skin cancer risk
Natural Options for Skin Cancer treatment of prevention
Research with vitamins or supplements for skin cancer prevention or
treatment is still very new, therefore no statements can be made with any
confidence. However, it is interesting to point out that certain herbs or
supplements have anti skin cancer activity in test tubes. I have listed some of
this skin cancer research a few paragraphs below. Here are some options:
Curcumin is an extract
from turmeric spice. You
can find
Curcumin for sale here.
Grape skin extract may
be helpful. You can find
Grape-Seed extract for sale here.
Silymarin found in
milk
thistle herb. You can find
Milk-Thistle for sale here.
Green tea extract appears
to be helpful in many types of cancer
Skin cancer and grape skin
extract
Chemicals found in grape seeds may help ward of skin cancer due to regular
exposure to the sun. Researchers from the University of Alabama, Birmingham
exposed hairless mice to ultraviolet-light. Some of the mice they fed a standard
diet supplemented with grape seed proanthocyanidins, while control mice were fed
a standard diet without this supplement. Dietary supplementation with grape seed
proanthocyanidins inhibited light-induced carcinogenesis, study. Mice
supplemented with grape seed proanthocyanidins had up to 65 fewer skin cancer
tumors than control mice did. Moreover, the tumors seen in grape seed
proanthocyanidins -supplemented mice were smaller than those seen in the control
mice. Based on the current findings, studies of grape seed extract for the
prevention of skin cancers in humans are warranted.
Skin cancer symptom - sign of Skin Cancer
The symptoms of non-melanoma skin cancer can usually be seen quite easily
since they tend to occur most often on sun exposed skin. It is helpful to detect
the early sign of skin cancer in order to avoid a larger section of skin from
being removed. Skin cancers can appear as
* A spot or sore that does not heal within several weeks
* A spot or sore that continues to itch, hurt, scab, crust or bleed for more
than a month
* Areas where the skin has broken down or ulcerates with no obvious cause, and
does not heal within several weeks. An ulcer is an area that is breaking down
and begins to get deeper. This can be called erosion.
Type of skin cancer
The main types of malignant skin cancer are:
* malignant melanoma,
* basal cell carcinoma (BCC),
* squamous cell carcinoma (SCC).
Basal and squamous cell carcinomas are often grouped together and referred to as
non-melanoma skin cancer.
Basal Cell Skin Cancer
Basal cell carcinoma is the most common form of skin cancer. Basal cell
skin cancers look like a small, slow growing shiny pink or red lump. If left,
they tend to become crusty, ulcerate or bleed. Basal cell skin cancer occurs on
the face, scalp, ears, hands, shoulders and back. Basal cell skin cancer can
occur on the nose. Some people misspell basil cell skin cancer as opposed to
basal cell.
Squamous cell skin cancers
Squamous cell carcinoma is the second most common type of skin
malignancy. Squamous cell skin cancer often appears as pink lumps. They may have
hard of scaly skin on the surface. They can bleed easily and ulcerate. They are
most often found on the face, neck, lips, ears, hands, shoulders, arms and legs.
Skin cancer treatment
The overall cure rate for basal cell carcinoma and squamous cell carcinoma
is directly related to the stage of the disease and the type of treatment used.
However, since neither basal cell carcinoma nor squamous cell carcinoma are
reportable diseases, precise 5-year cure rates are not known.
Other Types of Skin Cancer
Although basal cell carcinoma and squamous cell carcinoma are by far the most
frequent types of skin tumors, the skin can also be the site of a large variety
of malignant neoplasms. Other types of malignant disease include malignant
melanoma, cutaneous
T-cell lymphomas (e.g., mycosis fungoides), Kaposi’s sarcoma, extramammary
Paget’s disease, apocrine carcinoma of the skin, and metastatic malignancies
from various primary sites.
Melanoma Skin
Cancer
Australia has the highest skin cancer rate in the world and despite decades of
health campaigning the rate of melanoma, which is the most common kind of
skin cancer, is soaring.
Skin Cancer in Young Women
The incidence of two types of skin cancer has tripled among women under
age 40, a sign that tanning is still popular among the young despite warnings
about the harm it can cause. The rate of basal cell and squamous cell skin
cancers rose to 32 per 100,000 women under 40 in 2003 from 13 per 100,000 in the
late 1970s.
Risk of Melanoma with Skin Cancer
Women who've had common, highly curable forms of skin cancer may face a
heightened risk of the deadlier skin tumor melanoma. A study of more than 67,000
white postmenopausal women found that those with a history of non- melanoma skin
cancer were 70 percent more likely than other women to develop melanoma during
the study period. The findings suggest that there are genetic influences that
make some people vulnerable to both melanoma and non- melanoma skin cancers. Two
forms of non-melanoma skin cancer -- basal cell and squamous cell -- account for
the large majority of skin cancer cases, and are rarely fatal themselves. Based
on the new findings, though, the diseases can be added to the list of risk
factors for the deadlier melanoma. The results are based on data from the
Women's Health Initiative, a large study of U.S. women begun in 1994 that
collected detailed health and lifestyle information and followed up with
participants annually. Women with a history of non- melanoma skin cancer should
thorough skin examinations at frequent intervals to catch any new lesions early.
SOURCE: Cancer, February 1, 2006.
Sunscreens and Skin Cancer
Lawsuits filed in March, 2006 accuse
sunscreen makers of exposing
millions of people to skin cancer and other dangers through false and misleading
claims about the effectiveness of their sunscreen skin care products. The nine
suits - involving some of the most popular brands, including Coppertone, Banana
Boat, Hawaiian Tropic, Bullfrog and Neutrogena - charge that manufacturers
dangerously inflate claims about the protective qualities of sunscreens, lulling
consumers into believing they are safe from the dangers of prolonged skin
exposure to sun. Ultraviolet radiation from the sun is the leading cause of skin
cancer. The suits, filed in California, name as defendants Johnson & Johnson
Inc., Schering-Plough Corp., Playtex Products Inc., Tanning Research
Laboratories Inc. and Chattem Inc. The suits focus on labels that claim the
sunscreens protect equally against the sun's harmful UVA and UVB rays, and also
claims of how long supposed waterproof sunscreen remains effective in water. "In
truth and in fact ... as defendants knew or should have known, their skin
protection products, at best, only protect the skin against harmful UVA rays
with shorter wavelengths, while the skin remains exposed to harmful UVA rays
with longer wavelengths that penetrate deep within the skin," according to the
suits.
Organ Transplant patients and
Skin Cancer
Organ transplant recipients have a much higher than average risk of
developing the skin cancer squamous cell carcinoma. Dermatologists want
physicians, nurses and patients to be aware of this risk so that any skin
growths that look suspicious can be treated as early as possible.Transplant
recipients are 65-times more likely to develop squamous cell carcinoma,
involving not only the skin but other areas of the body, such as the throat,
vagina and the cervix. These cancers are the result of the powerful drugs these
patients must take to suppress their immune system so it doesn't attack and
reject the transplanted organ.
Skin Cancer research update
Silymarin and skin cancer prevention: anti-inflammatory, antioxidant and
immunomodulatory effects (Review).
Int J Oncol. 2005 Jan;26(1):169-76.
Several environmental and genetic factors are involved in skin cancer induction,
however exposure to chemical carcinogens and solar ultraviolet (UV) radiation
are primarily responsible for several skin diseases including skin cancer.
Chronic exposure of solar UV radiation to the skin leads to basal cell and
squamous cell carcinoma, and melanoma. Chemoprevention of skin cancer by
consumption of naturally occurring botanicals appears a practical approach and
therefore world-wide interest is considerably increasing to use these
botanicals. Sunscreens are useful but their protection is not ideal because of
inadequate use, incomplete spectral protection and toxicity. Silymarin, a plant
flavonoid isolated from the seeds of milk thistle (Silybum marianum), has been
shown to have chemopreventive effects against chemical carcinogenesis as well as
photocarcinogenesis in various animal tumor models. Topical treatment of
silymarin inhibited 7,12-dimethylbenz(a)anthracene-initiated and several tumor
promoters, like 12-O-tetradecanoylphorbol-13-acetate, mezerein, benzoyal
peroxide and okadaic acid, induced skin carcinogenesis in mouse models.
Similarly, silymarin also prevented UVB-induced skin carcinogenesis. Wide range
of in vivo mechanistic studies indicated that silymarin possesses antioxidant,
anti-inflammatory and immunomodulatory properties which may lead to the
prevention of skin cancer in in vivo animal models. The available experimental
information suggests that silymarin is a promising chemopreventive and
pharmacologically safe agent which can be exploited or tested against skin
cancer in human system. Moreover, silymarin may favorably supplement sunscreen
protection and provide additional anti-photocarcinogenic protection.
Skin cancer chemoprevention: strategies to save our skin.
Recent Results Cancer Res. 2003;163:151-64; discussion 264-6. Einspahr JG,
Bowden GT, Alberts DS. Arizona Cancer Center, University of Arizona, Tucson, AZ
There are over 1 million cases of skin cancer diagnosed yearly in the United
States. The majority of these are nonmelanoma skin cancer and are associated with
chronic exposure to ultraviolet light (UV). Actinic keratosis (AK) has been
identified as a precursor for squamous cell carcinoma, but not for basal cell
carcinoma. AKs are far more common than
SCC, making them excellent targets for chemoprevention. Cancer chemoprevention
can prevent or delay the occurrence of cancer in high-risk populations using
dietary or chemical interventions. We have developed strategies that have
rational mechanisms of action and demonstrate activity in preclinical models of
skin cancer. Promising agents proceed to phase I-III trials in subjects at high
risk of skin cancer. UV light induces molecular signaling pathways and results
in specific genetic alterations (i.e., mutation of p53) that are likely critical
to skin cancer development. UVB-induced changes serve as a basis for the
development of novel agents. Targets include inhibition of polyamine or
prostaglandin synthesis, specific retinoid receptors, and components of the Ras
and MAP kinase signaling pathways. Agents under study include: epigallocatechin
gallate (EGCG), a green tea catechin with antioxidant and sunscreen activity, as
well as UVB signal transduction blocking activity; perillyl alcohol, a
monoterpene derived from citrus peel that inhibits Ras farnesylation;
difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase and
polyamines; retinoids that target retinoid X receptors and AP-1 activity; and
nonsteroidal anti-inflammatory agents that inhibit cylooxygenase and
prostaglandin synthesis. We performed a series of Phase I-II trials in subjects
with multiple AK. For example, a phase II randomized trial of topical DFMO
reduced AK number, suppressed polyamines, and reduced p53 protein. Our goal is
to develop agents for use in combination and/or incorporation into sunscreens to
improve chemoprevention efficacy and reduce skin cancer incidence.
Skin Cancer Epidemic
There appears to be an unrecognized epidemic of skin cancer underway in
the United States. One in five Americans will develop skin cancer, and a
person's risk of the disease doubles if he or she has had five or more sunburns.
Basal and squamous cell carcinomas, the most common and treatable types of skin
cancers, had long been considered a problem only for people over 50. But it
appears that the percentage of women under 40 with the more common type, basal
cell, tripled between 1976 and 2003, while the rate of squamous cell cancers
increased four-fold. More than 50% of skin cancers occur on skin frequently
exposed to the sun, such as the head and neck, rather than the normal 90%. Most
of the remaining cancers are seen on the torso. This may be due to more
widespread use of tanning beds. Two types of ultraviolet (UV) light are
implicated in skin cancers. UVA, which penetrates deeper into the skin and
impairs its immune defenses, is more responsible for melanoma, the most deadly
type of skin cancer. UVB exposure causes sunburn, as well as squamous and basal
cell skin cancers. Tanning beds chiefly release UVA, although some also use UVB.
Skin cancer questions
Q. I am looking for research material on a natural treatment protocol for skin
cancer for a client. They have a squamous cell carcinoma in situ. Any
suggestions?
A. I don't have a particular skin cancer treatment protocol with
natural herbs or supplements, but listed at the top of the page are some herbs
and nutrients that may have an influence.
Additonal links on this web site
5-htp is popular for sleep
and mood
ahcc
is used for cancer treatment
carnosine is a strong
antioxidant
coq10 improves energy
Graviola is an herb
from the Amazonian rainforest
impotence herbal
treatment
Mangosteen extract
serrapeptase
is a strong enzyme
saw palmetto and pygeum
sexual enhancement product
Sitosterol or beta
sitosterol
Vinpocetine as brain
booster