Thyme herb health benefit leaf research and medical uses by Ray Sahelian, M.D.
October 12 2016

Thyme is a cultivated form of the wild thyme of the mountains European countries bordering the Mediterranean.

Parsley, Sage, Rosemary and Thyme
Of the dried culinary herbs tested, oregano, sage, peppermint, garden thyme, lemon balm, clove, allspice and cinnamon all contained very high concentrations of antioxidants. In a normal diet, intake of herbs may therefore contribute significantly to the total intake of plant antioxidants, and could be an even better source of dietary antioxidants than many other food groups such as fruits, berries, cereals and vegetables.

High quality herbs and spices to purchase
There are a number of herbs and spices that have great health benefit including basil, chamomile, cinnamon, curcumin, fennel, fenugreek, garlic, ginger, licorice, peppermint oil, turmeric, and thyme. These are all available as dietary supplements in capsules or tablets.

Simply Organic, Thyme, 0.78 oz (22 g)

Antimicrobial activity of Thyme
The extracts from thyme by water and ethanol, thyme essential oil, thymol and carvacrol were used as antimicrobial agents. The results show that all antimicrobial agents used have strong inhibition activity against Staphalococcus aureus, Bacillus subtilis, and Escherichia coli.

Antioxidant
Food Chem. December 1 2013. Effects of Salvia officinalis and Thymus vulgaris on oxidant-induced DNA damage and antioxidant status in HepG2 cells. The observed DNA-protective activity could be explained by both elevation of GPx activity in cells pre-treated with SO and TV and antioxidant activity of SO and TV.

Cancer prevention
Anticancer Drugs. 2015. Carvacrol inhibits proliferation and induces apoptosis in human colon cancer cells. Carvacrol is a major component of oregano and thyme essential oils and shows antitumor properties.

Gene protection
Cytotechnology. 2013. Ameliorative effects of thyme and calendula extracts alone or in combination against aflatoxins-induced oxidative stress and genotoxicity in rat liver.

Compounds in Thyme
Thyme herb contains many flavonoids including luteolin.

Thyme Research
Systemic availability and pharmacokinetics of thymol in humans.
J Clin Pharmacol. 2002.
Essential oil compounds such as found in thyme extract are established for the therapy of chronic and acute bronchitis. Various pharmacodynamic activities for thyme extract and the essential thyme oil, respectively, have been demonstrated in vitro, but availability of these compounds in the respective target organs has not been proven. Thus, investigation of absorption, distribution, metabolism, and excretion are necessary to provide the link between in vitro effects and in vivo studies. To determine the systemic availability and the pharmacokinetics of thymol after oral application to humans, a clinical trial was carried out in 12 healthy volunteers. Each subject received a single dose of a Bronchipret TP tablet, which is equivalent to 1.08 mg thymol. No thymol could be detected in plasma or urine. However, the metabolites thymol sulfate and thymol glucuronide were found in urine. Thymol sulfate, but not thymol glucuronide, was detectable in plasma. Peak plasma concentrations were reached after 2.0 hours. The mean terminal elimination half-life was 10 hours. Thymol sulfate was detectable up to 41 hours after administration. Urinary excretion could be followed over 24 hours. The amount of both thymol sulfate and glucuronide excreted in 24-hour urine was 16% of the dose.

In-vitro anti-inflammatory effect of Eucalyptus globulus and Thymus vulgaris: nitric oxide inhibition in J774A.1 murine macrophages.
J Pharm Pharmacol. 2004.
It is well known that nitric oxide (NO) plays an important role in the pathogenesis of inflammatory diseases. Eucalyptus globulus Labill. and Thymus vulgaris L. ( thyme ) have been used in traditional medicine in the treatment of bronchitis, asthma and other respiratory diseases. The present study focuses on the effects of these two extracts on NO production induced by lipopolysaccharide and interferon-gamma (IFN-gamma) in the murine macrophage cell line. E. globulus and thyme extracts significantly inhibited the enhanced production of NO induced by LPS and IFN-gamma in a dose-dependent manner. Treatment with these two extracts did not reduce cell viability at any dose used. Both eucalyptus and thyme showed significant scavenging of NO radicals released by an NO donor, PAPA-NONOate. Results also show that pre-treatment with E. globulus and thyme extracts significantly inhibits iNOS mRNA expression. This study thus suggests that the inhibition of net NO production by these two extracts may be due to their NO scavenging activity and/or their inhibitory effects on iNOS gene expression.

Human platelet aggregation inhibitors from thyme (Thymus vulgaris).
Phytother Res. 2002.
Two antiaggregant compounds, thymol (compound 1) and 3,4,3',4'-tetrahydroxy-5,5'-diisopropyl-2,2'-dimethylbiphenyl (compound 2) were isolated from the leaves of thyme. These compounds inhibited platelet aggregation induced by collagen, ADP, arachidonic acid and thrombin except that compound 2 did not inhibit platelet aggregation induced by thrombin. thyme maternity rosemary and thyme herbs thyme wild thyme parsley sage rosemary and thyme oil thyme.

Effect of thyme oil and thymol dietary supplementation on the antioxidant status and fatty acid composition of the ageing rat brain. thyme plant
Aromatic and Medicinal Plant Group, Scottish Agricultural College, Auchincruive, Ayr, UK.
Br J Nutr. 2000.
The present study measured changes in antioxidant enzyme activity in, and the phospholipid fatty acid composition of the ageing rat brain and tested whether dietary supplementation with thyme oil or thymol could provide beneficial effects. There were significant declines in superoxide dismutase and glutathione peroxidase activities and the total antioxidant status in the untreated rats with age, while thyme-oil- and thymol-fed rats maintained significantly higher antioxidant enzyme activities and total antioxidant status. The proportions of 18:2n-6, 20:1n-9, 22:4n-6 and 22:5n-3 in the brain phospholipids resulting from all three dietary treatments were significantly higher in 28-month-old rats than in 7-month-old rats. Only 20:1n-9 levels in 28-month-old thyme-oil- and thymol-treated rats were significantly higher than in the age-matched control. The proportion of 22:6n-3 in brain phospholipids, which declined with age in control rats, was also significantly higher in rats given either supplement. This latter finding is particularly important as optimum levels of 22:6n-3 are required for normal brain function. These results highlight the potential benefit of thyme oil as a dietary antioxidant. thyme research thyme oil. season of thyme wild mountain thyme thyme picture thyme and again
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Additioanl links of interest
Alfalfa herb, Amaranth grain,
Angelica pubescens herb, Banaba used for diabetes, and Clove herb. Saw palmetto a prostate herb, coq10 for better energy, dmae for sharper mind, 5-HTP for less stress.
Zaatar herbal mix, delicious Middle Eastern herbal mix with Thyme leaves, Oregano leaves, Sesame seeds, Salt, Soy oil, and Sumac.

buy Thyme Leaf, Nature's Way, 100 Capsules
Thyme (Thymus vulgaris), a sweet smelling herb, has been used traditionally for common winter aliments. It has been used extensively for the high thymol, phenol, and carvacol content in Thyme oil. Thyme is also a popular culinary herb.

Thyme Supplement Facts
Amount Per Serving:
Thyme (leaf) - 850 mg