Uroxatral side effects and benefit for prostate enlargement, adverse events, by Ray Sahelian, M.D.
April 10 2016

Uroxatral is a prescription medicine called an “alpha-blocker. Uroxatral is used in older men to treat the symptoms of benign prostatic hyperplasia (BPH). Uroxatral may help to relax the muscles in the prostate and the bladder which may lessen the symptoms of BPH and improve urine flow. The active ingredient is alfuzosin hydrochloride. the active Ingredient of Uroxatral is alfuzosin hydrochloride.

Int J Clin Pract. Sept 2013. Evaluation of patient outcome after discontinuation of alfuzosin treatment for benign prostatic hyperplasia: a multicentre, prospective study. When patients with BPH displayed symptomatic improvement upon treatment with alpha-blockers, the improvements were maintained in a select subpopulation of patients without the need to re-administer the alpha-blockers.

Urotraxal caution
Do not take Uroxatral if you have liver problems, are taking antifungal drugs like ketoconazole or HIV drugs called protease inhibitors, are already taking an alpha-blocker for either high blood pressure or prostate problems, are allergic to Uroxatral.

Uroxatral side effects
Possible Uroxatral side effects include drowsiness, fainting, chest pain, and allergic reactions. Some people also report Uroxatral side effects of feeling tired, having a runny nose, or a headache.

BMJ. 2015. The risk of fall and fracture with the initiation of a prostate-selective α antagonist: a population based cohort study. Do men starting treatment with prostate-specific α antagonists have increased risk of fall and fracture? Prostate-specific α antagonists are associated with a small but significant increased risk of fall, fracture, and head trauma, probably as a result of induced hypotension.

Q. Is saw palmetto as good as Uroxatral for prostate enlargement treatment?
   A. I have not seen any studies comparing the two in men who have BPH, but my guess would be that Uroxatral would be much more potent. However, saw palmetto, combined with other herbs and nutrients, may be helpful in some men with BPH.