Voacanga bark medical treatment and use
in medicine by
Ray Sahelian, M.D.
March 20 2016
Voacanga africana is used in the African country Cameroonian for the treatment of peptic ulcers. TN, al alkaloid from Voacanga bark, has gastric anti-secretory effects similar to histamine receptor blockers. Its cytoprotective and ulcer healing properties are related to its ability to strengthen gastric mucosal defenses perhaps through enhanced gastric mucus production.
Pharmaceutical Biology 2012. Chemistry and biology of the genus Voacanga. Herbal remedies have been employed for the treatment and management of various ailments since the beginning of human civilization. Voacanga is an extensive genus of the family Apocynaceae and consists of small trees inhabiting the tropical and subtropical regions of Africa. Voacanga plants have been used in the treatment of leprosy, diarrhea, and generalized edema, convulsions in children as well as to treat cases of orchitis, ectopic testes and gonorrhea. The aim of this review is to present as much information as was established from the available scientific literature. The present review comprises the ethnopharmacological, phytochemical and therapeutic potential of the plant genus Voacanga. The present review reports on 111 natural products as found in 44 references compiled from the major databases, viz., Chemical Abstracts, Science Direct, SciFinder, PubMed, Dr. Dukes Phytochemical and Ethnobotany, CIMER, and InteliHealth. An exhaustive survey of the literature revealed that indole alkaoids and steroids constitute the major classes of phytoconstituents of this genus. Pharmacological reports revealed that products derived from this genus have been used for the treatment of cancer, and for CNS, cardiotonic, antituberculosis, acetylcholinesterase (AChE), butyrylcholinesterase, antagonistic, anti-diarrheal activities.
Synergistic and potentiating effects of ranitidine and two new anti-ulcer compounds from Enantia chlorantha and Voacanga africana in experimental animal models.
Pharmazie. 2002. Department of Animal Biology and Physiology, University of Yaounde I, Cameroon.
TN, an alkaloid from the fruit of Voacanga africana and a protoberberine-type alkaloid (7,8-dihydro-8-hydroxypalmatine), obtained from the bark of Enantia chlorantha were tested for ulcer preventive and antisecretory activity in combination with ranitidine. When tested alone (50 and 100 mg/kg, p.o.), TN and 1 achieved their anti-ulcer actions through reduced gastric secretion and improved mucus production. 1:1 combinations of 1 and the antisecretory agents (25/25 and 50/50 mg/kg) resulted in significant reduction of ulceration under highly acidic conditions, suggesting potentiating effects. A combination of TN and ranitidine led to synergistic antisecretory effects.
Ibogaine in Voacanga
It appears that voacanga africana has a powerful substance called Ibogaine.
Kachile is a registered Swiss foundation, that has as its mission to stimulate entrepreneurial activity in West Africa to alleviate poverty. Kachile means change in local language Baoule and we guide local businesses to make their own lasting social and economic change. Kachile is subcontracting the trade of voacanga africana and griffonia simplificonia pharmaceutical seeds to local farming companies. In order to stimulate improved incomes for local farmers in the region I am seeking to secure them a foreign importer to buy their voacanga africana and griffonia simplicifolia pharmaceutical seeds. Would Physician Formula be interested in this offer of high quality voacanga africana and griffonia simplicifolia pharmaceutical seeds and to source from a fair and just poverty alleviation scheme? We can guarantee several tonnes of voacanga africana seeds and 20 tonnes griffonia simplicifolia growing in Ghana for sale. Along with several tonnes of each in Mali. The first installment of griffonia will be ready for shipment on 20th January 2010 since harvest commences on December 20 2009. The voacanga can be shipped immediately, as soon as we get the order we can dispatch. For further information, please do not hesitate to ask me. Kind regards, Victoria Alice Kachile Co-Founder & Chief Operations Officer Grand Bassam, Cote d'Ivoire.