Zallouh Research in rodents
An intriguing study in male rats showed that zallouh, when given one
time, enhanced sexual activity, and also raised blood levels of testosterone.
However, when zallouh was given daily for 10 days, it actually reduced sexual
activity, and also reduced testosterone levels. This is difficult to explain but
my guess would be that perhaps the dose of zallouh given to the rats was too
high.
Human research
As of March 2009, I am not aware of studies with this herb done in humans
and that have been published in peer reviewed journals.
Passion Rx - Formulated by Ray Sahelian, M.D.
Passion Rx does not have zallouh herb.

How quickly does Passion Rx work?
Passion Rx provides results that are sometimes seen within hours, but
continue to improve the next day, and over several days of use. Our feedback
thus far indicates more than 80% user satisfaction.
Renowned physician
and herbal expert
Dr. Ray Sahelian, M.D, author of
Natural Sex Boosters, has discovered a
exotic
aphrodisiac herbal extracts from the Amazon jungle, India, China, Malaysia, and Africa,
that, when combined, improve sexual desire and performance, as well as
to simply enhance sexual pleasure. Passion Rx provides a
natural option for those looking for an alternative to synthetic drugs.
The potent nutrients and herbal extracts in Passion Rx include
acetylcarnitine, ashwagandha,
catuaba,
choline, cnidium monnieri,
coleus forskohlii, dmae, epimedium,
maca herb,
mucuna pruriens, muira puama, passion flower,
pfaffia paniculata,
rehmannia, rhodiola, shilajit
substance,
tribulus terrestris,
tongkat ali. Passion Rx does not have
zallouh at this time.
Another version of Passion Rx is available with
yohimbe, an herb from Africa.
Zallouh
Safety
The crude oil from zallouh can enhance erectile function in rodents, however
zallouh appears to be toxic if used for a long period of time in high doses. In mice, the ingestion of 3 mg/kg of aqueous extract of zallouh for six weeks
inhibited social aggression. Body weight and other sexual accessory organ weights were
significantly reduced. The ingestion of high doses of zallouh by male mice resulted in a
reduction of their fertility.
Sometimes herbs have different effects when given for brief periods
as opposed to prolonged periods. Also, the dose of an herb makes a significant
difference on how effective it is. Too much can be counterproductive and cause
side effects.
Zallouh Summary
At this point it is difficult to make any firm recommendations regarding the use
of zallouh to enhance libido
or to treat erectile dysfunction. Occasional use appears to be safe, but long term use is discouraged
until more is known as to the safety of chronic zallouh ingestion. It is quite
possible that the dosages used in rodent studies were quite high compared to
what humans would ingest for sexual enhancement purposes.
In the meantime, if you are interested in a doctor formulated
herbal sexual product, consider Passion Rx, which is quite popular. The version
with yohimbe works quicker.
Compounds found in zallouh
herb
Zallouh extract has
sesquiterpenes called
ferutinin, teferin and teferdin.
Tests in rodents
Some of the studies with zallouh herb or extract in rodents have not shown
encouraging results. This could be due the dosage used (too little or too much),
or the different response rodents would have to this herb than humans.
Role of ferutinin in the impairment of female sexual function induced by Ferula
hermonis.
Physiol Behav. 2006 Dec 30; Zavatti M, Montanari C, Zanoli P.
Department of Biomedical Sciences, Section of Pharmacology, and National
InterUniversity Consortium for the Study of Natural Active Principles (CINSPAN),
University of Modena and Reggio Emilia, Via Campi 287, 41100 Modena, Italy.
In the present study, we evaluated the effects of single components of
Ferula hermonis extract on female rat sexual behavior. Ovariectomized rats
hormonally primed with estradiol benzoate and progesterone were acutely treated
by oral gavage with ferutinin, teferin and teferdin. Thereafter they were tested
for: a) partner preference, b) receptivity, c) proceptivity, d) paced mating
behavior. In the partner preference test, the choice of the female for a
sexually active male was not influenced by the different treatments. Similarly,
during the paced mating test, the contact-return latencies as well as the
percentage of exits from the male compartment were not different in control and
treated rats. Therefore none of the three compounds showed the capacity to alter
sexual motivation. On the other hand, ferutinin, but not teferin and teferdin,
significantly inhibited female receptivity. These results suggest a primary role
of ferutinin in the impairment of sexual behavior elicited by Ferula hermonis
extract in hormone primed-female rats.
Opposite effect of acute and subchronic treatments with Ferula hermonis
( zallouh ) on
copulatory behavior of male rats.
Int J Impot Res. 2003 Dec;15(6):450-5.
Sexually potent and sluggish/impotent male rats were orally treated with an
extract of zallouh (Ferula hermonis) (30 and 60 mg/kg). The acute zallouh administration
stimulated sexual motivation in potent rats and improved copulatory performance
in sluggish/impotent rats. This last effect was elicited only by the higher
zallouh dose, which, in parallel, increased serum testosterone levels in rats. On the
contrary, when the extract was subchronically administered (10 days) a marked
reduction in the percentage of rats achieving ejaculation was detected, together
with a general impairment of the copulatory pattern. Furthermore, the repeated
administration of the zallouh extract resulted in a
significant reduction of testosterone levels in comparison with controls. The
present results discourage a repeated assumption of zallouh, while
suggesting its acute administration to improve the performance in sexual
dysfunctions.
Comments: it appears that zallouh is more suited for
short term use and not necessarily appropriate for long term
sexual health. One
option is to use a zallouh supplement for a few days and then take a couple of
week or more off.
A comparative study of Ferula hermonis root extracts ( zallouh ) and sildenafil on
copulatory behavior of male rats.
Fitoterapia. 2003 Apr;74(3):242-6.
The effect of 600 mg/kg given by oral route to rats of Ferula hermonis ( zallouh ) roots
extracts was evaluated on
sexual behavior of male rats. Petroleum ether and ethyl acetate extracts
of zallouh produced a significant decrease in both the mount rate (MR) and the intromission
rate (IR), significant prolongation of intromission latency (IL) was observed
when these extracts were compared with both controls and sildenafil. Methanolic
zallouh
extract produced a significant increase in MR while no effect has been observed
on IR or IL in comparison with control. The effect of zallouh water extract was not
significantly different from controls for the MR and IR, but there was a
significant prolongation in the IL.
Zallouh herbal supplement questions
Q. Do you know where I can buy zalouh pills to
enhance sex drive
?
A. If you do a search on the internet, you can find some websites
that sell zallouh capsules. By the way, the correct spelling is zallouh, not
zalouh.
Additional information of interest
List
of herbs for health and
medical conditions.
A list of
sexual enhancement herbs,
lj100 is a potent tongkat ali
extract.
Clavo_huasca is an herb
from the Amazon rainforest used as an aphrodisiac.
Graviola is touted
an anti tumor herb.
Penis enlargement
pills, do they work?
Xanthoparmelia
lichen is sometimes found in sexual products.
Mangosteen
has xanthone compounds.
Ahcc
sale
serrapeptase
proteolytic enzyme, saw palmetto
herb.
Better orgasm with
Passion Rx which is a product that can be a solution in some people who have
impotence. Many herbal
sexual products are available on the market including
VigRx pill and
Zenerx capsule.
Coq10 supplement for mitochondrial
energy.
5-HTP can be used by people
who have too much libido, 5-HTP can dampen sexual desire.