Zallouh herb for sexual enhancement by Ray Sahelian, M.D.,

Zallouh is made from the dried root of the herb Ferula Hermonis which grows at a height of about 2000 meters above sea level on the side of Mount Hermoun between Lebanon and Syria. Zallouh has been used historically in the region as an aphrodisiac, but it has only been in the past few years that scientists have evaluated it's chemical properties. Zallouh contains a number of compounds, including sesquiterpenes. Years ago articles appeared in several magazines that called zallouh the " Lebanese Viagra."

Zallouh Research in rodents
An intriguing study in male rats showed that zallouh, when given one time, enhanced sexual activity, and also raised blood levels of testosterone. However, when zallouh was given daily for 10 days, it actually reduced sexual activity, and also reduced testosterone levels. This is difficult to explain but my guess would be that perhaps the dose of zallouh given to the rats was too high.

Human research
As of March 2009, I am not aware of studies with this herb done in humans and that have been published in peer reviewed journals.

Passion Rx - Formulated by Ray Sahelian, M.D.
Passion Rx does not have zallouh herb.

How quickly does Passion Rx work?
Passion Rx provides results that are sometimes seen within hours, but continue to improve the next day, and over several days of use. Our feedback thus far indicates more than 80% user satisfaction.

Renowned physician and herbal expert Dr. Ray Sahelian, M.D, author of Natural Sex Boosters, has discovered a exotic aphrodisiac herbal extracts from the Amazon jungle, India, China, Malaysia, and Africa, that, when combined, improve sexual desire and performance, as well as to simply enhance sexual pleasure. Passion Rx provides a natural option for those looking for an alternative to synthetic drugs.

The potent nutrients and herbal extracts in Passion Rx include acetylcarnitine, ashwagandha, catuaba, choline, cnidium monnieri, coleus forskohlii, dmae, epimedium, maca herb, mucuna pruriens, muira puama, passion flower, pfaffia paniculata, rehmannia, rhodiola, shilajit substance, tribulus terrestris, tongkat ali. Passion Rx does not have zallouh at this time. Another version of Passion Rx is available with yohimbe, an herb from Africa.


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Zallouh Safety
The crude oil from zallouh can enhance erectile function in rodents, however zallouh appears to be toxic if used for a long period of time in high doses. In mice, the ingestion of 3 mg/kg of aqueous extract of zallouh for six weeks inhibited social aggression. Body weight and other sexual accessory organ weights were significantly reduced. The ingestion of high doses of zallouh by male mice resulted in a reduction of their fertility.
   Sometimes herbs have different effects when given for brief periods as opposed to prolonged periods. Also, the dose of an herb makes a significant difference on how effective it is. Too much can be counterproductive and cause side effects.

Zallouh Summary
At this point it is difficult to make any firm recommendations regarding the use of zallouh to enhance libido or to treat erectile dysfunction. Occasional use appears to be safe, but long term use is discouraged until more is known as to the safety of chronic zallouh ingestion. It is quite possible that the dosages used in rodent studies were quite high compared to what humans would ingest for sexual enhancement purposes.
   In the meantime, if you are interested in a doctor formulated herbal sexual product, consider Passion Rx, which is quite popular. The version with yohimbe works quicker.

Compounds found in zallouh herb
Zallouh extract has
sesquiterpenes called ferutinin, teferin and teferdin.

Tests in rodents
Some of the studies with zallouh herb or extract in rodents have not shown encouraging results. This could be due the dosage used (too little or too much), or the different response rodents would have to this herb than humans.

Role of ferutinin in the impairment of female sexual function induced by Ferula hermonis.
Physiol Behav. 2006 Dec 30; Zavatti M, Montanari C, Zanoli P. Department of Biomedical Sciences, Section of Pharmacology, and National InterUniversity Consortium for the Study of Natural Active Principles (CINSPAN), University of Modena and Reggio Emilia, Via Campi 287, 41100 Modena, Italy.
In the present study, we evaluated the effects of single components of Ferula hermonis extract on female rat sexual behavior. Ovariectomized rats hormonally primed with estradiol benzoate and progesterone were acutely treated by oral gavage with ferutinin, teferin and teferdin. Thereafter they were tested for: a) partner preference, b) receptivity, c) proceptivity, d) paced mating behavior. In the partner preference test, the choice of the female for a sexually active male was not influenced by the different treatments. Similarly, during the paced mating test, the contact-return latencies as well as the percentage of exits from the male compartment were not different in control and treated rats. Therefore none of the three compounds showed the capacity to alter sexual motivation. On the other hand, ferutinin, but not teferin and teferdin, significantly inhibited female receptivity. These results suggest a primary role of ferutinin in the impairment of sexual behavior elicited by Ferula hermonis extract in hormone primed-female rats.

Opposite effect of acute and subchronic treatments with Ferula hermonis ( zallouh ) on copulatory behavior of male rats.

Int J Impot Res. 2003 Dec;15(6):450-5.
Sexually potent and sluggish/impotent male rats were orally treated with an extract of zallouh (Ferula hermonis) (30 and 60 mg/kg). The acute zallouh administration stimulated sexual motivation in potent rats and improved copulatory performance in sluggish/impotent rats. This last effect was elicited only by the higher zallouh dose, which, in parallel, increased serum testosterone levels in rats. On the contrary, when the extract was subchronically administered (10 days) a marked reduction in the percentage of rats achieving ejaculation was detected, together with a general impairment of the copulatory pattern. Furthermore, the repeated administration of the zallouh extract resulted in a significant reduction of testosterone levels in comparison with controls. The present results discourage a repeated assumption of zallouh, while suggesting its acute administration to improve the performance in sexual dysfunctions.
     Comments: it appears that zallouh is more suited for short term use and not necessarily appropriate for long term sexual health. One option is to use a zallouh supplement for a few days and then take a couple of week or more off.

A comparative study of Ferula hermonis root extracts ( zallouh ) and sildenafil on copulatory behavior of male rats.
Fitoterapia. 2003 Apr;74(3):242-6.
The effect of 600 mg/kg given by oral route to rats of Ferula hermonis ( zallouh ) roots extracts was evaluated on sexual behavior of male rats. Petroleum ether and ethyl acetate extracts of zallouh produced a significant decrease in both the mount rate (MR) and the intromission rate (IR), significant prolongation of intromission latency (IL) was observed when these extracts were compared with both controls and sildenafil. Methanolic zallouh extract produced a significant increase in MR while no effect has been observed on IR or IL in comparison with control. The effect of zallouh water extract was not significantly different from controls for the MR and IR, but there was a significant prolongation in the IL.

Zallouh herbal supplement questions
Q. Do you know where I can buy zalouh pills to
enhance sex drive ?
   A. If you do a search on the internet, you can find some websites that sell zallouh capsules. By the way, the correct spelling is zallouh, not zalouh.

Additional information of interest
List of herbs for health and medical conditions. A list of sexual enhancement herbs, lj100 is a potent tongkat ali extract. Clavo_huasca is an herb from the Amazon rainforest used as an aphrodisiac. Graviola is touted an anti tumor herb. Penis enlargement pills, do they work? Xanthoparmelia lichen is sometimes found in sexual products. Mangosteen has xanthone compounds. Ahcc sale serrapeptase proteolytic enzyme, saw palmetto herb. Better orgasm with Passion Rx which is a product that can be a solution in some people who have impotence. Many herbal sexual products are available on the market including VigRx pill and Zenerx capsule. Coq10 supplement for mitochondrial energy. 5-HTP can be used by people who have too much libido, 5-HTP can dampen sexual desire.