Akarkara Spilanthes acmella
April 10 2016 by Ray Sahelian, M.D.

Benefit, why take it
Akarkara flower heads are chewed to relieve toothache and other mouth related troubles. Leaves are used externally in treatment of skin diseases. Leaf decoction is used as diuretic and lithotriptic. Akarkara whole plant is used in treatment of dysentery. The botanical name of this herb is Spilanthes acmella.

Akarkara (Paracress), a common spice, has been administered as a traditional folk medicine for years to cure toothaches, stammering, and stomatitis. Previous studies have demonstrated its diuretic, antibacterial, and anti-inflammatory activities.

Adv Pharmacol Sci. 2013. Phytochemistry, Pharmacology and Toxicology of Spilanthes acmella: A Review. Spilanthes acmella is an important medicinal plant, found in tropical and subtropical countries mainly India and South America. Popularly, it is known as toothache plant which reduces the pain associated with toothaches and can induce saliva secretion. Various extracts and active metabolites from various parts of this plant possess useful pharmacological activities. Literature survey proposed that it has multiple pharmacological actions, which include antifungal, antipyretic, local anaesthetic, bioinsecticide, anticonvulsant, antioxidant, aphrodisiac, analgesic, pancreatic lipase inhibitor, antimicrobial, antinociception, diuretic, vasorelaxant, anti-human immunodeficiency virus, toothache relieve and anti-inflammatory effects.

Spilanthol reduces activation of NF-kappaB, which negatively regulates the production of proinflammatory mediators.