Carob is originally from the eastern Mediterranean region and the
western part of Asia. The gum from carob seeds is called locust bean gum.
The dried, powdered pods of the carob plant are used in herbal medicine.
Carob is used as a thickener and in foods,
cosmetics, pharmaceuticals,
and paints. Carob has enjoyed increased popularity in recent years as a
low-fat, low-calorie, low-caffeine alternative to chocolate. Carob itself
does not contain any caffeine. However it does contain traces of theobromine
chemical.
Theobromine is related to caffeine, but it is a milder
stimulant. It is the stimulant found in chocolate. Carob powder is
available for sale as well as carob chips. They can be mixed with the no
calorie sweetener stevia to improve the taste. If you have an interest in
obtaining polyphenols from cocoa, consider a cacao supplement.
Carob caffeine content
Q. I have atrial fibrillation (heart rhythm disturbance) and cannot have coffee and chocolate.
Someone told me I should use carob in place of chocolate – will carob
cause heart palpitations? I have been palpitation-free on several meds for
10 months and do not want to jeopardize this. Is there caffeine or
anything else in carob that would cause palpitations?
A. Carob does not contain caffeine. However, carob has very small
amounts of theobromine which are not likely to cause heart palpitations
when consumed in small amounts.
Carob Research
Identification and quantification of polyphenols in carob fruits (Ceratonia
siliqua) and derived products by HPLC-UV-ESI/MSn.
J Agric Food Chem. 2004.
The polyphenolic patterns of carob pods (Ceratonia siliqua) and
derived products were identified and quantified using high-performance
liquid chromatography-UV absorption-electrospray ion trap mass
spectrometry after pressurized liquid extraction and solid-phase
extraction. In carob fiber, 41 individual phenolic compounds could be
identified. Carob pods contain 448 mg/kg extractable polyphenols
comprising gallic acid, hydrolyzable and condensed tannins, flavonol-glycosides,
and traces of isoflavonoids. Among the products investigated, carob fiber,
a carob pod preparation rich in insoluble dietary fiber (total polyphenol
content = 4142 mg/kg), shows the highest concentrations in flavonol-glycosides
and hydrolyzable tannins, whereas roasted carob products contain the
highest levels of gallic acid. The production process seems to have an
important influence on the polyphenolic patterns and quantities in carob
products.
Carob pulp preparation rich in insoluble fibre lowers total and LDL
cholesterol in hypercholesterolemic patients.
Eur J Nutr. 2003.
Recently, insoluble fibre from carob pulp has been found to
affect blood lipids in animals in a similar manner as soluble dietary fibre. To investigate whether a carob pulp preparation containing high
amounts of insoluble fibre has a beneficial effect on serum cholesterol in
humans. Volunteers (n = 58) with hypercholesterolemia were recruited to
participate in a randomised, double- blind, placebo-controlled and parallel arm
clinical study with a 6 week intervention phase. All participants consumed daily
both, bread (two servings) and a fruitbar (one serving) either with or
without a total amount of 15 g/d of a carob pulp preparation (carob fibre). Serum concentrations of total, LDL and HDL cholesterol and triglycerides
were assessed at baseline and after week 4 and 6. The consumption of
carob fibre reduced LDL cholesterol by 10%. The LDL:HDL
cholesterol ratio was marginally decreased in the carob fibre
group compared to the placebo group. Carob fibre consumption also
lowered triglycerides in females by 11%. Lipid lowering
effects were more pronounced in females than in males. Daily
consumption of food products enriched with carob fibre shows beneficial effects
on human blood lipid profile and may be effective in prevention and treatment of
hypercholesterolemia.
Isolation and structure elucidation of the major individual polyphenols in
carob fibre.
Food Chem Toxicol. 2003.
Although it is already known that carob fibre contains several classes of
polyphenolic substances, a comprehensive analysis of these has not been
conducted to date. Therefore, the major polyphenolic compounds were extracted
with organic solvents, and, following fractionation by normal-phase column
chromatography on silicic acid, their structures were elucidated by
liquid-chromatography electrospray-ionisation mass spectrometry (LC-ESI),
nano-electrospray-ionisation mass spectrometry (ESI-MS), and gas-chromatography
mass spectrometry (GC-MS). In addition, complete 1H and 13C NMR assignments were
obtained for the isolated gallotannins 1,2,6-tri- and
1,2,3,6-tetra-O-galloyl-beta-D-glucose. Carob fibre was found to contain a rich
variety of phenolic antioxidants. A total of 24 polyphenol compounds were
identified with a yield of 3.94 g/kg (dry weight). The profile was dominated by
gallic acid in various forms: free gallic acid (42% of polyphenols by weight),
gallotannins (29%), and methyl gallate (1%), while simple phenols, mainly
cinnamic acid, made up about 2% of the total. Flavonoids represented 26% of the
polyphenols, and the major components were identified as the glycosides
myricetin- and quercetin-3-O-alpha-L-rhamnoside (ca. 9% and 10%, respectively).
These data indicate that carob fibre is rich in both amount and variety of
phenolic antioxidant substances, and its inclusion in the diet may have
chemopreventive properties.
Effect of carob bean on gastric emptying time in Thai infants.
Asia Pac J Clin Nutr. 2003.
Thickening agents, such as carob bean gum or galactomannan, have been
successfully administered for the treatment of gastroesophageal reflux in
infants. To study the effect of carob bean gum on gastric emptying and to
symptoms of regurgitation, we recruited 20 full term Thai infants without pathological gastroesophageal reflux. In conclusion, carob bean gum, as a thickening agent,
improves the clinical symptoms of regurgitating infants, but does not
significantly alter the gastric emptying physiology. carob recipe
Antiproliferative effects of Ceratonia siliqua on mouse hepatocellular
carcinoma cell line.
Fitoterapia. 2002.
Extracts from pods and leaves of carob (Ceratonia siliqua) were tested for
their ability to inhibit cell proliferation of mouse hepatocellular carcinoma
cell line (T1). The two extracts showed a marked alteration of T1 cell
proliferation in a dose-related fashion reaching the maximal effect at 1 mg/ml.
Moreover, we demonstrated that leaf and pod extracts were able to induce
apoptosis in T1 cell lines after 24-h treatment mediating a direct activation of
the caspase 3 pathway. HPLC analysis revealed the presence of gallic acid, epigallocatechin-3-gallate and (-) epicatechin-3-gallate in pod and leaf
extracts, compounds well known to exert antiproliferative effects. Their
concentration reached 6.28 mg/g in carob leaves and 1.36 mg/g in carob pods
extract. The discovery that carob pod and leaf extracts contained
antiproliferative agents could be of practical importance in the development of
functional foods and/or chemopreventive drugs.
Extraction and purification from Ceratonia siliqua of compounds acting on
central and peripheral benzodiazepine receptors.
Fitoterapia. 2002.
The presence of molecules with high affinity for central and peripheral
benzodiazepine receptors was determined in the pod and leaves of Ceratonia
siliqua (carob). The amount of the substances able to selectively bind the
central benzodiazepine receptor recovered from carob pods and leaves was
respectively 12 and 18 ng diazepam equivalent/g. The amount of compounds active
on peripheral benzodiazepine receptor in both carob pods and leaves was higher
in comparison with the central one. In particular the compounds acting on
peripheral benzodiazepine receptors were found to be extremely concentrated in
the young leaves. The presence of substances with
central benzodiazepine activity in carob extracts seems of great importance in
view of the possibility to use carob extract as potential natural products with anxiolytic-sedative effects. Moreover, the prevalence in leaves of substances
acting on peripheral benzodiazepine receptor suggests the possible utilisation
of leave extracts as chemopreventive agents.
Inquiries
Q. Please explain the difference between cacao bean and carob bean? I was told
cacao aka chocolate is habit forming while carob is healthy. And I myself eat
carob (1 tablespoon spread) daily to control my epileptic seizures.
A. I am not aware of carob being helpful for seizures. Both carob
and cacao have substances that are healthy and, in my opinion, it is a good idea
to have small amounts of a variety of different plants and plant extracts rather
than focusing on only one or a few.