Hemidesmus indicus herb, root and plant information and side effects, research studies
Indian Sarsaparilla herb is a species of plant that is found in South Asia. The dried roots contain Hemidesmus or ananthamul.
Hemidesmus indicus is an indigenous Ayurvedic herb used in soft drinks in India
Antioxidant effect of Hemidesmus indicus on
ethanol-induced hepatotoxicity in rats.
J Med Food. 2007; Saravanan N, Nalini N. Department of Biochemistry and
Biotechnology, Annamalai University, Annamalainagar, Tamilnadu, India.
The antioxidant effect of the ethanolic root extract of Hemidesmus indicus was
studied in rats with ethanol-induced hepatotoxicity. Administering 20% ethanol
(5 g/kg of body weight/day) for 60 days to male Wistar rats resulted in
significantly decreased body weight and increased liver/body weight ratio. The
liver marker enzymes, aspartate transaminase (AST), alanine transaminase (ALT),
alkaline phosphatae (ALP), gamma-glutamyl transpeptidase (GGT), and lactate
dehydrogenase (LDH), were elevated. Our data indicate that treatment with
Hemidesmus indicus extract offers protection against free radical-mediated
oxidative stress in plasma, erythrocytes, and liver of animals with
ethanol-induced liver injury.
Pregnane glycoside from Hemidesmus indicus as a
potential anti-oxidant and anti-dyslipidemic agent.
Nat Prod Res. 2010: Sethi A, Bhatia A, Srivastava S, Bhatia G, Khan
MM, Khanna AK, Saxena JK. Department of Chemistry, University of Lucknow,
Lucknow, India.
A new pregnane glycoside hindicusine was isolated from the CHCl(3)-EtOH (3 : 2)
extract of Hemidesmus indicus, whose structure was established on the basis of
spectroscopic studies. The glycoside and its acetylated derivative were
evaluated for their anti-oxidant and anti-dyslipidemic activities.