Levitra is an oral drug therapy for the treatment of erectile dysfunction. I have taken it on several occasions and it does work to enhance erectile function, usually within a few hours, for me. Also known by the chemical name vardenafil, it is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Like impotence drugs Viagra and Cialis, Levitra is a phosphodiesterase-5 inhibitor (PDE-5). All of these drugs function in essentially the same way. In smooth muscle cells, cGMP (cyclic guanosine monophosphate) mediates smooth muscle relaxation. The more cGMP, the more the muscles can relax, the more blood can flow in, and the better the erection. PDE-5 breaks down cGMP, so PDE-5 inhibitors keep this from happening, helping to maintain high levels of cGMP. A possible advantage of Levitra is that it is very selective in attacking PDE-5 without affecting other isoenzymes. This allows a smaller dose to have the same effect as a larger dose of Viagra (an average Levitra dose is 10mg while an average Viagra dose is 50mg), even though the two drugs essentially work the same way.
Aging Male 2014. The real-life perception of
efficacy, attitude, satisfaction and safety of vardenafil therapy (REPEAT): a
prospective, non-interventional, observational study. This study assessed the
improvement in relationship quality, effectiveness and safety associated with
Levitra for the treatment of erectile dysfunction (ED). The study was conducted
in 1433 centres across 21 countries and comprised a baseline patient visit and
up to four follow-up visits during an observational period of 1 year.
Relationship quality, happiness, satisfaction with treatment, and safety and
tolerability were assessed by physician interviews and patient and partner
questionnaires. Relationship quality, assessed by a relationship questionnaire, was improved at
last observation carried forward, compared with baseline, in both patients and
partners and satisfaction with the effectiveness of treatment was high. Levitra
was well tolerated and adverse events were consistent with the known safety
profile of phosphodiesterase type 5 inhibitors.
Viagra Cialis Levitra danger, safety, toxicity
A small number of men have lost eyesight in one eye
some time after taking Viagra, Cialis or Levitra. This type of vision loss is
called non-arteritic anterior ischemic optic neuropathy (NAION). People who have
a higher chance for NAION include those who have pre-existing eye problems,
heart disease, are over 50 years old, have diabetes, have high blood pressure,
have high cholesterol, or smoke. FDA has approved new labels for Viagra, Cialis
and Levitra to include information on possible eyesight loss (NAION). Stop using
them if you have reduced vision or loss in your eyesight.
Get medical help right away.
Alternative to Levitra, natural aphrodisiacs
There are
sexual
enhancement alternatives to
Viagra Cialis and Levitra.
There are herbal supplements that support healthy stamina,
libido, sensation, and
sexuality in men and women. In recent years science has made breakthroughs in
the understanding of sexual dysfunction. But, for hundreds of years,
civilizations around the world have known about locally grown herbs that achieve
wonderful results with far fewer side effects than prescription drugs.
The potent herbal extracts that enhance sexual pleasure include ashwagandha, catuaba, cnidium monnieri,
coleus forskohlii, horny goat weed, maca, mucuna pruriens, muira puama, passion flower,
pfaffia paniculata, rhodiola, shilajit, tribulus terrestris extract,
and tongkat ali.
Viagra Cialis Levitra alternative - herbs in a natural formula called Passion Rx include ashwagandha herb, Catuaba, Cnidium, Muira Puama, Tribulus Terrestris extract with saponins, Tongkat ali, and Yohimbe.
Levitra side effects,
risk, toxicity, is it safe?
The side effects of Levitra are many. The most common side effects
are stuffy nose or runny nose, flushing, muscle aches and a headache. Less
frequent side effect include priapism, an erection that won't go away. A serious
Levitra side effect is that involving eyesight. Vision changes, such as seeing a
blue tinge to objects or having difficulty telling the difference between the
colors blue and green can occur, along with a potentially serious loss of
vision, particularly in those who have vascular disease.
Use for spinal
cord Injury
The impotence drug Levitra is helpful for men who have erectile
dysfunction caused by spinal cord injury. Researchers evaluated the efficacy and
tolerability of 12 weeks of treatment with Levitra versus placebo in 418 men
with erectile difficulties due to a traumatic spinal injury. Erectile function
improved with Levitra, known chemically as vardenafil, whereas there was little
improvement in erectile function in the placebo group. Men treated with Levitra
had a 76 percent success rate for penetration (versus 41 percent with placebo)
and a higher success rate for maintaining the erection.
Levitra Research for ED
Levitra is a synthetic, highly selective, and potent inhibitor of
phosphodiesterase-5 which competitively inhibits cyclic guanosine monophosphate
(cGMP) hydrolysis and thus increases cGMP levels. It is clinically approved for
treatment of erectile dysfunction in men, including diabetic and post prostate
surgery patients.
Vardenafil for
erectile dysfunction: a
systematic review and meta-analysis of clinical trial reports.
Markou S. 1Akrata Medical Center, Greece.
Trials of the efficacy and safety of Levitra in the treatment of male
erectile dysfunction (ED) were meta-analysed. Trials were eligible if they
included men with ED, compared Levitra with placebo, were randomized, were at
least of 12 weeks duration, and assessed clinically relevant outcomes. Two
reviewers independently evaluated study quality and extracted data in a
standardized fashion. Nine trials (6809 men) met the inclusion criteria. In
results pooled from seven fixed-dose trials, Levitra increases the Erectile
Function domain of the International Index of Erectile Function questionnaire by
6 units (weighted mean difference (WMD)). Levitra also increases the percentage
of erections firm enough to allow vaginal penetration and the percentage of
sexual attempts that were successful per participant . The percentage of men agreeing with the statement that 'the treatment
they have been taking over the past 4 weeks improved their erections', is also
in favor of Levitra. These efficacy variables appeared
greater at higher doses, although there are no significant differences between
10 and 20 mg dose. Specific adverse events with Levitra included
flushing, dyspepsia, headache, and rhinitis. The drug was not significantly
associated with serious cardiovascular events or death. Levitra, in all
treatment regimens, shows to possess superior efficacy to placebo in the
treatment of patients with erectile dysfunction.
Levitra not only enables men with erectile dysfunction (ED) to engage successfully in sexual intercourse, it also significantly improves partner satisfaction. Dr. Edwards of White House Surgery, Chipping Norton, UK, and his colleagues randomly assigned 260 men with erectile dysfunction to Levitra or an inactive "placebo" pill. Every 4 weeks over the 12-week study. When the effects of treatment for men and their partners were considered, Levitra significantly improved satisfaction scores compared with placebo orgasm satisfaction (60 percent vs 32 percent for men, 56 percent vs 32 percent for partners), pleasure (67 percent vs 44 percent for men; 64 percent vs 38 percent for partners), ease of erection (64 percent vs 41 percent for men and 60 vs 37 percent for partners), satisfaction with erection (60 percent vs 28 percent for men; 58 percent vs 27 percent for partners), satisfaction with the medication (62 percent vs 31 percent for men; 58 percent vs 30 percent for partners).
J Sex Medicine. 2011. Efficacy and safety of vardenafil for the treatment of erectile dysfunction in men with metabolic syndrome: results of a randomized, placebo-controlled trial. This is the first study to assess the efficacy and safety of vardenafil, taken alone, for ED therapy in a population of men who all had metabolic syndrome. Although baseline erectile function in these patients was low, vardenafil treatment was associated with significant improvements in erectile function and rates of successful intercourse, and was well tolerated.
Raynaud's phenomenon
Arch Intern Med. 2012. Vardenafil for the treatment of raynaud phenomenon: a
randomized, double-blind, placebo-controlled crossover study.
Testimonial sent by email
I just wanted you (and maybe your subscribers) to know that I've tried
Viagra & Cialis & Levitra. For me, and though they all work similarly, I prefer
Levitra far more than the others, mainly because it is the only one that does
not cause me a headache. I also don't seem to get that red-skin-flush appearance
(or feeling) with it.
Questions, reports
I read in a Levitra forum online that results come in a few hours. Can it be mixed with alcohol?
The results occur
within several hours. I would not recommend mixing alcohol and Levitra unless
the alcohol is kept to one drink only.
Q. I heard Levitra can cause blindness. Is that true?
A. There have been several cases reported of an
association between Cialis, Levitra and blindness. If you have a 20 mg
pill, only use a portion to avoid the adverse reactions. Dosing with
a smaller amount reduces side effects. High doses pose a danger if a
person takes it who has heart disease or is on heart medicines.
Q. I read in a Levtria brochure that Levitra is better than Viagra. Is that
true?
A. Some people prefer Levitra, others Cialis, and still
others Viagra. It's a personal preference.
Q. Is Levitra sold online pill ? I want to order Levitra but don't know who to
trust.
A. Yes, you can order or buy Levitra online but a
prescription is needed. You can buy Levitra at an online pharmacy but make sure
they are legitimate and require a prescription.
Q. What's your opinion on cheapest generic Levitra?
A. I would be surprised if a generic Levitra sold on an
online pharmacy site would be effective. If you buy generic Levitra, you may be
wasting your money. You are better off to purchase it from a reliable
pharmacy even if the cost is higher, Get a Levitra prescription from your
doctor.
Q. Do you have a Levitra testimonial on your site?
A. We focus mostly on natural Levitra alternatives, but
we have heard that it works in 60 to 80 percent of users.
Q. I tried a Levitra sample my doctor gave me, and it did not work but gave me a
headache.
A. Not all drugs, medicines, or supplements work in
everyone. The dosage can make a difference, too.
Q. Does a Levitra pill work in a woman?
A. I doubt if women find it to be of benefit.
History and background Information
2004 - German drug maker Bayer won approval to sell a new
impotence drug across the European Union that it hopes will win business from
Pfizer's breakthrough blockbuster Viagra.
Bayer expects Levitra, which it is marketing with Britain's GlaxoSmithKline, to
bring in up to 1 billion euros ($1.1 billion) a year, once it secures approval
in the United States. Bayer said the round, orange pills would go on sale in
Germany later this month. U.S. approval is expected later this year.
``This is an extremely important step for our pharmaceuticals business,'' chief
executive Werner Wenning said. ``We believe that Levitra has the potential to
become a new blockbuster,''
The battle for dominance in a condition that affects about one in five men is
expected to be fierce. Cialis, a drug from Eli Lilly & Co. and Icos Corp. won
European approval last year and is also expected to hit pharmacies in the United
States later this year.
All the drugs work in the same manner so some doctors believe it may be
difficult for Levitra and Cialis to establish themselves when Viagra has been
around for five years. Other say the drugs are an option for those whose
conditions aren't helped by Viagra.
Sales of Pfizer's blue, diamond-shaped Viagra pills totaled $1.7 billion last
year. It is the only significant prescription product for erectile dysfunction.
``We think the competition will expand the overall market. Erectile dysfunction
is still underdiagnosed,'' said a Pfizer spokeswoman. ``But in the end, we think
patients will choose Viagra because it has a track record.''
Leverkusen-based Bayer has a lot riding on Levitra. It is still suffering from
the 2001 withdrawal of the cholesterol lowering drug Lipobay, marketed in the
United States as Baycol, after it was linked to dozens of deaths. Bayer Gets OK
for New
Impotence Drug.
Marketing
Bayer initially developed Levitra and manufactures the drug. The orange/yellow
Levitra pill has the "Bayer cross" trademark on it, Bayer registered the "Levitra"
trademark, owns the Levitra.com domain, etc. Since GlaxoSmithKline has a better
marketing infrastructure for prescription drugs, Bayer joined with
GlaxoSmithKline to market the drug jointly. The two companies describe the
relationship this way: Levitra is "co-developed and co-promoted by Bayer and
GlaxoSmithKline".
More
questions
Q. Can Levitra be taken with horny goat weed, lipoic acid,
vinpocetine, or the
mind booster
acetylcarnitine?
A. We prefer impotence drugs to be
taken on days when herbs are not being used.
Q. I purchased Passion Rx recently and have a
question about its use if a patient also uses ED medications. I saw some
disclaimer info for this
Viagra-alternative
and among the usual drugs it warned against using
with Levitra was yohimbe.
Do you know why Yohimbe might have a negative interaction with this class of ED
drugs and is there enough Yohimbe in the Passion Rx formula developed by
developed
Dr. Sahelian
to be of any
concern. You advise to take the supplement first thing in morning and if I was
to use Levitra the same day it would be 12 hours or more after.
A. Yohimbe is a potent herb and Passion Rx is a potent combination.
Usually the positive effects of many sex herbs is delayed for a day or two, One
option is to take Passion Rx the day before the use of Levitra, but not the same
day. This way you can have some of the benefit of the Passion Rx but it won't be
too hard on your body taking the herbal combination and Levitra the same day.
Another option is to take the Passion Rx 2 days in a row and then the third day
take Levitra. Be very careful and use much lower amounts if you have heart
problems or blood pressure problems and have approval by your doctor. In some
people herbal Viagra
alternatives work so well that they may not need Levitra or Viagra, or may use
them in lower dosages and less frequently.
Q. Sir, is it safe to take arginine with
Levitra for erectile dysfunction? I am 30 years old and I am healthy. The only
medical condition I am currently being treated for is GERD (acid reflux
disease). My doctor prescribed me Nexium and Famotidine. If it is safe to
combine the two, how much arginine would be safe with a 10 mg dose of Levitra. I
would ask my own doctor but not two many doctors are familiar with herbs and
dietary supplements.
A. We can only provide general information on Levitra and arginine.
It is up to the consumer and their doctor to determine whether to mix drugs and
supplements. We are not very impressed with the ability of arginine to be
effective for impotence.
Q. Can I take passion Rx and use Viagra or Levitra
the same day?
A. Not the same day. Passion Rx can be taken the day before and
perhaps a little lower dosage of the pharmaceutical drug the day of intimacy.
And, we suggest medical approval.
Q. I have an erectile dysfunction prescription for Levitra. I
have had this prescription for a more than 2 years at the 20 mg. dose. My empty
prescription bottles would likely fill a brown grocery bag more than halfway. On
some occasions, I have doubled my dose, which I now realize to be a grand
mistake. I am 43 years old, and in otherwise excellent physical condition,
however, Lately, I have had increased chest pressure surrounding my heart. I
have not done enough cardio-vascular exercise, I eat badly, and heart disease
runs in my family tree. How much of factor is Levitra on my heart? And What is
the factor of a double dose on my heart? And lastly, What is the long term
effect of this drug? I need to schedule a full physical and make changes to my
diet and exercise, Is it still safe to take this drug?
A. Heart disease is something that is important to rule out before
using Levitra on a regular basis. It is impossible for us to know whether
Levitra had an influence on your chest pains. Those with erectile dysfunction
are more likely to have heart disease than those that do not have ED. Your
decision to seek a full physical evaluation is wise.
Q. If my husband's doctor prescribed Cialis and Levitra after
my husband's prostate removal --is it correct to assume that Passion Rx might be
able to help in the same way, without the negative side effects of those drugs?
My husband gets a mild, all day headache and dry mouth from those drugs. not
very conducive to motivation to have sex. His robotic prostate operation was
supposed to be nerve sparing. But it has been 7 months and he is still not able
to have anything close to an erection, even with the use of those drugs. (He
didn't start them till 6 months out, due to problems with urinary incontinence.
) His doc says have sex every other day! But the desire is not really there,
even with the drug, and so far they have no impact.
A. It is difficult to predict in any one person how they will
respond to Passion Rx or any herbal or pharmaceutical sexual enhancer. Passion
Rx does help improve desire and performance in the majority of users and most
people who take this natural herbal formula like the effects.