Lomatium dissectum
December 22 2015

Planetary Herbals introduces a botanical long revered by Native Americans for enhanced immune and respiratory support. Full Spectrum Lomatium Respiratory and Immune Support The resinous roots of Lomatium dissectum were extensively used by traditional Native peoples of the Pacific Northwest and Northern Nevada where the plant is indigenous. It was used both as a food staple and for support of a healthy respiratory system.

J Ethnopharmacol. 1995. Antiviral screening of British Columbian medicinal plants. One hundred methanolic plant extracts were screened for antiviral activity against seven viruses. Twelve extracts were found to have antiviral activity at the non-cytotoxic concentrations tested. The extracts of Rosa nutkana and Amelanchier alnifolia, both members of the Rosaceae, were very active against an enteric coronavirus. A root extract of another member of the Rosaceae, Potentilla arguta, completely inhibited respiratory syncytial virus. A Sambucus racemosa branch tip extract was also very active against respiratory syncytial virus while the inner bark extract of Oplopanax horridus partially inhibited this virus. An extract of Ipomopsis aggregata demonstrated very good activity against parainfluenza virus type 3. A Lomatium dissectum root extract completely inhibited the cytopathic effects of rotavirus. In addition to these, extracts prepared from the following plants exhibited antiviral activity against herpesvirus type 1: Cardamine angulata, Conocephalum conicum, Lysichiton americanum, Polypodium glycyrrhiza and Verbascum thapsus.

J Nat Prod. 1988. Native American food and medicinal plants, 8. Water-soluble constituents of Lomatium dissectum. A continuing investigation of the umbellifer Lomatium dissectum has resulted in the isolation of a known flavonoid [1] and three coumarin glycosides [2-4], two of which are previously unreported. One of these new compounds [4] contains apiose, a sugar uncommon in the coumarins. The ichthyotoxicity of the plant extracts has been traced to the tetronic acids isolated earlier in this study.

Lomatium californicum
Phytother Res. 2006. Antibacterial activity of components from Lomatium californicum. The isolation, characterization and bioactivity testing of compounds from Lomatium californicum (Nutt.) are described. Ethyl acetate and hexane extracts of the roots of L. californicum were subjected to vacuum liquid chromatography (VLC), flash column chromatography (FCC) and separation by normal- and reverse-phase high-performance liquid chromatography (HPLC). Six compounds were isolated successfully and characterized by 1D and 2D nuclear magnetic resonance (NMR) experimentation. The bioactivity of the known compounds (+)-falcarindiol, coniferyl ferulate, ferulic acid and (Z)-ligustilide were confirmed against the Gram-positive bacteria Bacillus subtilis and Staphylococcus aureus. The known compounds senkyunolide I and trans-neocnidilide were also isolated but in too small a quantity for similar testing.