Polygonum aviculare herb - bird knotgrass plant benefit

Polygonum aviculare is an herb with antioxidant properties. This herb has many compounds including sitosterol, oleanolic acid tetramethoxyflavanone, naphthoquinone, and 6-methoxyplumbagin.

As of 2017, no human studies with polygonum aviculare herbal medicine could be found on Medline. Therefore it is difficult to know the proper dosage and extract potency to use.

Clinical uses of polygonum avicilare
Not enough western human research is available to determine if polygonum avicular has a role to play in health and disease.

Antioxidants in Polygonum aviculare
Antioxidant activity of extract from Polygonum aviculare
Biol Res. 2006. Department of Life Science, Chang Gung University, Tao-Yuan, Taiwan, China.
Whether Polygonum aviculare has antioxidant activity is unknown. In this study, dried Polygonum aviculare L. was extracted by ethanol. The antioxidant activities of extract powder were examined by free radical scavenging assays, superoxide radical scavenging assays, lipid peroxidation assays and hydroxyl radical-induced DNA strand scission assays. The results show that the IC50 value of Polygonum aviculare extract is 50 microg/ml in free radical scavenging assays, 0.8 microg/ml in superoxide radical scavenging assays, and 15 microg/ml in lipid peroxidation assays, respectively. Furthermore, Polygonum aviculare extract has DNA protective effect in hydroxyl radical-induced DNA strand scission assays. The total phenolics and flavonoid content of extract is 677 microg/g and 112 microg/g. The results indicate that Polygonum aviculare extract clearly has antioxidant effects.

Polygonum aviculare for gingivitis
Clinical effect of a Mexican sanguinaria extract Polygonum aviculare L. on gingivitis.
J Ethnopharmacol. 2001. Dental Research Center, School of Dentistry, Villas de San Agustin, Bo. de Santa Cruz, Metepec, C.P, Edo. de Mexico, Mexico.
The effectiveness of a natural Mexican Sanguinaria extract Polygonum aviculare against gingivitis, was assessed in 60 male dentistry students between the ages of 18 and 25 years. Over a period of 2 weeks, these students used the Sanguinaria extract (1 mg/ml) in oral rinse twice daily as a unique oral health measurement (no tooth-brushing was allowed). The O'Leary Plaque Index and the Loe and Silness Gingivitis Index were recorded at baseline (day 0) in all the subjects. Also, a complete prophylaxis was performed after both indices were obtained. The antibacterial and antiinflammatory effects of the extract were evaluated on days 7, 11 and 14. The results showed that the Mexican Sanguinaria extract in oral rinse significantly decreased gingivitis. In contrast, a significant increase in dental plaque was observed; however, the consistency of this plaque permitted its mechanical flushing easily. From this study, it is concluded that the Mexican Sanguinaria extract in oral rinse can be employed supportively in the therapy of gingivitis.

Q. I recently purchased a bulk quantity of knotweed powder primarily for the high resveratrol content. However, in doing subsequent research, I realized there are several varieties of the knotweed (polygonum) plant. I understand that Polygonum Cuspidatum contains concentrated amounts of resveratrol and is a primary source for many supplements. I purchased the Polygonum Aviculare variety of knotweed powder. Are the levels of resveratrol in this Polygonum Aviculare comparable? How much resveratrol is in each variety?
   A. We don't have knowledge of the resveratrol content of Polygonum Aviculare. Polygonum aviculare extract clearly has antioxidant effects but we don't know how much of that is due to which types of flavonoids.