Two New Age foods which contain high concentrations of whole food nutrients are
the single-celled microalgae chlorella and spirulina. They are promoted as functional
foods, defined as products derived from natural sources, whose consumption is
likely to provide health benefits. These foods are used as a
supplement or ingredient or as a complete food to enhance the performance of the
human body, or improve a specific bodily function. Spirulina contains unusually high levels of gamma-linolenic acid, an
essential polyunsaturated fatty acid.
Spirulina Plankton usually has:
Vitamin A (Beta Carotene)
Vitamin B-1 (Thiamin)
Vitamin B-2 (Riboflavin)
Niacin B vitamin
Folate (as folic acid)
Vitamin B-12
Iron
Phosphorus
Magnesium
Phycocyanin
Linolenic Acid
Gamma Linolenic Acid
Chlorophyll
Carotenoids
Superoxide Dismutase
Omega-3 Fatty Acids include
alpha linolenic acid
Boron mineral.
Benefit
Due to high content of highly valuable proteins,
amino acids, vitamins, beta-carotene and other pigments, mineral substances,
fatty acids and polysaccharides, spirulina has been found suitable for use as
a bioactive additive. It stimulates the immune system by enhancing the
production of antibodies and cytokines and thus improving resistance of
humans, mammals, chickens and fish to infections. Under the influence of spirulina, macrophages, T and B cells are activated. Spirulina sulfolipids have proved to be effective
against HIV. Preparations obtained from SP biomass have also been found active against herpes virus, cytomegalovirus, influenza virus, etc. Spirulina preparations are regarded as functional products contributing to the
preservation of the resident intestinal microflora, especially lactic acid bacilli and
bifidobacteria, and to a decrease in the level of Candida albicans. The
biological activity with respect to microorganisms holds good promise for using these microalgae as components of culture media.
Mini Rev Med Chem. June 2013. Nutritional and medical applications of spirulina microalgae. Spirulina spp. and its processing products are employed in agriculture, food industry, pharmaceutics, perfumery and medicine. Spirulina has several pharmacological activities such as antimicrobial (including antiviral and antibacterial), anticancer, metalloprotective (prevention of heavy-metal poisoning against Cd, Pb, Fe, Hg), as well as immunostimulant and antioxidant effects due to its rich content of protein, polysaccharide, lipid, essential amino and fatty acids, dietary minerals and vitamins. This article serves as an overview, introducing the basic biochemical composition of this algae and moves to its medical applications.
Allergic rhinitis
Effects of a Spirulina-based dietary supplement on cytokine
production from allergic rhinitis patients.
J Med Food. 2005. Division of Rheumatology/Allergy and Clinical Immunology, University
of California at Davis, School of Medicine, Davis, California, USA.
We evaluated the impact of a Spirulina based dietary supplement (Earthrise
Nutritionals, Inc., Irvine, CA) on patients with allergic rhinitis by
assessing the production of cytokines [interleukin (IL)-4, interferon (IFN)-gamma,
and IL-2] critical in regulating immunoglobulin E-mediated allergy. These
results indicate that Spirulina can modulate the Th profile in patients
with allergic rhinitis by suppressing the differentiation of Th2 cells
mediated, in part, by inhibiting the production of IL-4. To our knowledge,
this is the first human feeding study that demonstrates the protective
effects of Spirulina towards allergic rhinitis.
Cholesterol level
Hypocholesterolemic effect of spirulina in patients with hyperlipidemic
nephrotic syndrome.
J Med Food. 2002 . Department of Foods and Nutrition,
M S University of Baroda, Vadodara, Gujarat, India.
In nephrotic syndrome, large amounts of plasma proteins are lost in urine,
causing a decrease in the plasma oncotic pressure. This leads to enhanced
hepatic synthesis of albumin and other proteins, including lipoproteins,
causing a secondary hyperlipidemia. In this study 23 patients (age 2 to 13
years) with nephrotic syndrome received either medication (group I) or
medication plus 1 gram a day Spirulina. It can be concluded that spirulina
capsules, rich in antioxidants, GLA, amino acids, and fatty acids, helped
reduce the increased levels of lipids in patients with hyperlipidemic
nephrotic syndrome.
Diabetes
One study shows two grams a day improves improves lipid
profile and glycated proteins in
NIDDM.
Exercise
performance, energy, anti-fatigue
Preventive effects of Spirulina platensis on skeletal muscle damage under
exercise-induced oxidative stress.
Eur J Appl Physiol. 2006. Sport Science Research
Center, National Taiwan College of Physical Education, Taichung, Taiwan.
The effects of spirulina supplementation on preventing skeletal muscle
damage on untrained human beings were examined. Sixteen students
volunteered to take Spirulina platensis in addition to their normal diet
for 3-weeks. The results showed that plasma concentrations of
malondialdehyde (MDA) were significantly decreased after supplementation
with spirulina. The activity of blood superoxide dismutase (SOD) was
significantly raised after supplementation with spirulina or soy protein.
Both of the blood glutathione peroxidaes (GPx) and lactate dehydrogenase (LDH)
levels were significantly different between spirulina and soy protein
supplementation. In addition, the lactate concentration was higher and the
time to exhaustion was significantly extended in the spirulina trail.
These results suggest that ingestion of Spirulina platensis showed
preventive effect of the skeletal muscle damage and that probably led to
postponement of the time of exhaustion during the all-out exercise.
Int J Food Sci Nutr. 2016, A randomized, double blind, placebo controlled study of spirulina supplementation on indices of mental and physical fatigue in men. Spirulina may increase people's ability to resist mental and physical fatigue. This study tested that hypothesis in a randomized, double blinded, placebo controlled study in men. After 1 week, a 3 g/day dose of spirulina produced a small, but statistically significant increase in exercise output (Kcals consumed in 30 min exercise on a cross trainer machine). A mathematical based mental fatigue test showed improved performance 4 h after the first time of supplementation as well as 8 weeks later. Similarly, a subjective survey for a sense of physical and mental fatigue showed improvement within 4 h of the first supplementation as well as 8 weeks later. These results show that spirulina intake can affect fatigue in men.
Immune
system
Apparently spirulina has the ability to stimulate the immune system
which could be beneficial in some individuals, and potentially harmful in
those who already have an overactive immune system or an autoimmune
condition. Therefore, spirulina is not advised to be taken regularly for those who have
lupus,
autoimmune thyroiditis, pemphigus vulgaris, and other such
conditions.
Liver protection
Food Chem. December 2013 . Protective effect of Spirulina platensis enriched
in phenolic compounds against hepatotoxicity induced by CCl4.
Availability
Spirulina is available as a tablet and you can also find spirulina powder.
Sometimes you can find a combination
chlorella spirulina product.
It is available as Hawaiian spirulina and
other species that include pacifica in addition to the standard
platensis. Recently organic spirulina has been sold.
Side effects, safety, risk, allergy
Activation of autoimmunity following use of immunostimulatory herbal
supplements.
Section of Dermatology, University of Chicago, IL.
Arch Dermatol. 2004.
Evidence for the scientific basis of purported therapeutic
effects and adverse effects of herbal supplements continues to grow. Many herbal
supplements are touted for their immunostimulatory properties, and both in vitro
and in vivo experiments have supported this claim. Although this explains their
beneficial effects in preventing or curtailing disease, to our knowledge, no
immunostimulatory herbal supplements have been reported to exacerbate disorders
of immune system overactivity. We describe 3 patients whose
autoimmune disease onset and/or flares correlated with ingestion of herbal
supplements with proven immunostimulatory effects. Echinacea and the alga
Spirulina platensis are implicated in 2 patients' flares of pemphigus vulgaris,
and a supplement containing the algae Spirulina platensis and Aphanizomenon
flos-aquae was ingested by a third patient days before both onset and a severe
flare of dermatomyositis. The third patient showed heterozygosity for a tumor
necrosis factor alpha (TNF-alpha) promoter polymorphism (-308A), leading to
increased production of TNF-alpha, which may have predisposed her to developing
dermatomyositis. Immunostimulatory herbal supplements such as
spirulina may
exacerbate preexisting autoimmune disease or precipitate autoimmune disease in
persons genetically predisposed to such disorders. Increased production of TNF-alpha
may play a role, although more research is needed to clarify the mechanisms of
such phenomena.
Food Chem Toxicol. 2014. Anaphylaxis to Spirulina
confirmed by skin prick test with ingredients of Spirulina tablets. Arthrospira
platensis, blue-green microalgae, has high content in proteins, γ-linoleic acid
and vitamins and therefore gained popularity as food supplement. According to
the Food and Agriculture Organization of the United Nations Spirulina is also an
interesting alternative and sustainable protein source with the growing world
population. We present a case of a 17-year-old male, who developed anaphylaxis
the first time he ingested a Spirulina tablet. Skin prick test with diluted
Spirulina tablet was positive. Further skin prick testing with separated
ingredients (Spirulina platensis algae, silicon dioxide, inulin and magnesium
stearate) was only positive for Spirulina platensis algae and negative in
controls, confirming the allergy was caused by Spirulina and not by one of the
additives.
Research studies
Protective effect of Spirulina fusiformis on
chemical-induced genotoxicity in mice.
Fitoterapia. 2004.
Spirulina fusiformis given by oral route to mice significantly inhibit the genotoxicity induced by cisplatin and
urethane. In addition, a significant reduction in the extent of lipid
peroxidation with concomitant increase in the liver enzymatic (GPx, GST, SOD,
CAT) and non-enzymatic (reduced glutathione) antioxidants were observed with
spirulina.
Evaluation of the efficacy of a plant adaptogen
in the pathognic therapy of primary tuberculosis in children
Lik Sprava. 2003.
The use of spirulina and its efficiency have been studied in a comparative
aspect as a systemic biocorrector, in a combined treatment of
tuberculosis in 26
children. It has been ascertained that application of spirulina as a
pathogenetic means of remediation permits shortening the intoxication syndrome
regression time, reducing the frequency of adverse reactions in administering
antituberculous preparations.
Effects of spirulina on serum lipids, erythrocyte
membrane fluidity and vascular endothelial cells in tail-suspended rats
Space Med Med Eng 2003.
To study the changes of erythrocyte membrane fluidity, serum lipid
and vascular endothelial cell caused by simulated weightlessness in rats and the
beneficial effect of spirulina. Method: Thirty male SD rats were divided into 3
groups: free control group (group A) and two simulated weightlessness groups
(groups B, C). Rats in group A and B were fed with normal forage, and the rats
in group C were fed with normal forage supplemented with 5% (W/W) spirulina.
Result: Levels of serum CHO, HDL, TG, HDL-C/CHO and erythrocyte membrane
fluidity decreased significantly, and number of vascular endothelial cells in
plasma increased markedly in group B as compared with those in group A; The
ratio of LDL-C/HDL-C, and atherosclerosis index (AI) decreased, number of
vascular endothelial cells significantly lowered; level of CHO, HDL-C and value
of the IDmax of plasma as well as erythrocyte membrane fluidity remarkedly
increased in group C with spirulina compared with those in group B. Spirulina can improve the physiological conditions of erythrocyte membrane
fluidity, serum lipid and vascular endothelial cell caused by simulated
weightlessness in rats. algae spirulina loss spirulina weight.
Protective effect of Spirulina on lead induced
deleterious changes in the lipid peroxidation and endogenous antioxidants in
rats.
Phytother Res. 2003.
The present study aims to investigate the protective effect of Spirulina on
lead-induced changes in the levels of lipid peroxidation and endogenous
antioxidants in liver, lung, heart, kidney and brain of rats. Levels of
elemental lead were also measured in the organs of rats in all experimental
groups. In the liver, lung, heart and kidney of lead-exposed animals, there was
a significant increase in the lipid peroxidation and a decrease in the levels of
endogenous antioxidants. Although, Spirulina did not affect the deposition of
lead in organs apart from the brain, simultaneous administration of Spirulina to
lead exposed animals significantly inhibited lipid peroxidation and restored the
levels of endogenous antioxidants to normal. Spirulina had a
significant effect on scavenging free radicals, thereby protecting the organs
from damage caused by the exposure to lead. Further more it led to a
significant decrease in the deposition of lead in the brain.
Emails
I have been consuming spirulina product over the past few
months. I recently came across some articles which warned that the
benefits claimed by manufacturers have not had much evidence
behind them but on the contrary there may be ill effects as it may
contain toxins and heavy metals. I feel concerned after reading the
articles. I would like to ask if you can provide assurance to users that
spirulina products are safe to consume and that there will be no toxic
effects from consumtion. Thank you.
We cannot claim that any supplement is safe for long
term use. There just isn't enough known about long term use of spirulina
or other supplements for us to have a good understanding of their benefits
and risks. This is one reason why I consistently mention that people
should take breaks from the use of supplements just in case there's
something harmful going on that we don't know about. By taking breaks from
use, we can get many benefits from the supplements, and minimize risks.
Do you have any reason to feel that a food
such as spirulina would be good for increasing a man's semen / ejaculate
volume and quality, and therefore
fertility? I ask
this based on spirulina's reported high quality protein and amino acid
content, and based on my understanding that Peruvian
Maca is also good for
this, partly because of its own amino acid content. So could this be the
case? (I see ejaculate volume as a sign of good fundamental nutrition
right down to the cellular level, let me add.) And further, what other
foods are good for increasing a man's ejaculate volume especially -and by
extension quality, etc.?
And would Passion Rx have these benefits as well?
Spirulina could help with the above but we have no
studies to rely on. Maca has been studied in fertility and could have
benefits in terms of sperm volume. I think fish oils or eating cold water
fish could help with semen volume. Passion Rx seems to have a number of
benefits in terms of semen volume, orgasm power, etc.
Can I take
saw palmetto with
spirulina?
The safety of combining herbs and supplements mostly rests on
the dosage. In most cases, as long as the amounts are low, many
supplements can be combined. However, each person is unique and there are
many factors to consider in combining supplements.
Was just
wondering why you recommend skipping 1 week a month while taking a spirulina supplement.
My recommendations of taking breaks
are not specific to this supplement. As a general guideline, I think it
may be wise to take breaks since no long term human studies have been done
to determine benefits and side effects. By taking breaks, potential side
effects would be minimized.
I was wondering if spirulina would interfere with
someone who has Von Willebrand disease Type I. Could you please get back to me
on this issue.
I have not seen any research on this interaction.
Just a question regarding Spirulina, is it normal to experience an
increase in heart rate? I feel that after just 3 tablets which is less than the
bottle recommendation. It prevents me from taking it too late at night as my
heart rate remains elevated for at least an hour and a half thereafter. I use it
as a cheaper alternative to Barley Green which strangely had a very calming
effect.
I have not had such feedback yet from users, but it is
possible. You may wish to try another brand to see if the same results occur.
purchase Spirulina supplement 500 mg per tablet
For many years Spirulina platensis has been a good choice for supplementing a vegetarian diet. This special blue-green algae is a good source of numerous vitamins, minerals, carotenoids, and essential fatty acids that are hard to maintain at adequate levels with a vegetarian diet. Most notable is the high quality protein, which contains all nine essential amino acids. Spirulina cell walls do not contain cellulose to slow down digestion. Spirulina is naturally grown and harvested without herbicides or pesticides. Also consider Chlorella supplements.
Buy Spirulina 500 mg
Suggested Use: 1 to 3 spirulina tablets daily with meals. Take a week off from use each month.
Supplement Facts Healthy Origins, Organic Spirulina, 500 mg, 720 Tablets | ||
Serving Size: 3 Tablets | ||
Servings Per Container: 60 | ||
Amount Per Serving | % DV | |
Calories | 5 | |
Total Carbohydrates | <1 g | |
Vitamin A (as beta-carotene) | 3,600 IU | 72% |
Protein | 1 g | 2% |
Parry Organic Spirulina (Arthrospira platensis) | 1.5 g | † |
Phycocyanin | 240 mg | † |
Total Carotenoids | 5,625 mcg | † |
Beta-Carotene | 2,250 mcg | † |
Zeaxanthin | 1,875 mcg | † |
Vitamin B12 | 1.5 mcg | 25% |
Chlorophyll | 15 mg | † |
Gamma Linolenic Acid (GLA) | 15 mg | † |
† Daily Value not established Percent Daily Values (DV) are based on a 2,000 calorie diet. |